RegulonDB RegulonDB 10.8: Gene Form
   

tqsA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

pntB tqsA ydgV H-NS TSS_1887 TSS_1887 TSS_1886 TSS_1886 TSS_1885 TSS_1885 TSS_1884 (cluster) TSS_1884 (cluster) TSS_1883 TSS_1883 TSS_1882 TSS_1882 tqsAp tqsAp mdtJp mdtJp TSS_1880 TSS_1880

Gene      
Name: tqsA    Texpresso search in the literature
Synonym(s): ECK1596, G6859, b1601, ydgG
Genome position(nucleotides): 1673913 --> 1674947 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 50.24
External database links:  
ASAP:
 ABE-0005350
ECHOBASE:
 EB3687
OU-MICROARRAY:
 b1601
PortEco:
 tqsA
STRING:
 511145.b1601
COLOMBOS: tqsA


Product      
Name: autoinducer 2 exporter
Synonym(s): TqsA, YdgG
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 37.543
Isoelectric point: 9.355
Motif(s):
 
Type Positions Sequence
62 -> 82 VLAVSILMTIIVMAMVLLLAY
293 -> 313 LVVFLSLIFWGWLLGPVGMLL
222 -> 242 FAFVWGLLAFALNYIPNIGSV
258 -> 278 FYEALLVLAGYLLINLVFGNI
150 -> 170 SIFLLLLTVLFMLLEVPQLPG

 
Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.9.B - Putative uncharacterized transport protein
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015562 - efflux transmembrane transporter activity
biological_process GO:1905887 - autoinducer AI-2 transmembrane transport
GO:0009372 - quorum sensing
GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Jindal S., et al., 2019
[2] Ren D., et al., 2004
External database links:  
ECOCYC:
 G6859-MONOMER
ECOLIWIKI:
 b1601
INTERPRO:
 IPR002549
PANTHER:
 PTHR21716
PFAM:
 PF01594
PRIDE:
 P0AFS5
PRODB:
 PRO_000024096
REFSEQ:
 NP_416118
SMR:
 P0AFS5
UNIPROT:
 P0AFS5


Operon      
Name: tqsA         
Operon arrangement:
Transcription unit        Promoter
tqsA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1880 1673778 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_1882 1674496 forward nd [RS-EPT-CBR] [3]
  promoter TSS_1883 1675550 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_1884 (cluster) 1676197 reverse For this promoter, there
Read more > 		[RS-EPT-CBR] [3]
  promoter TSS_1885 1676203 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_1886 1676256 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_1887 1676312 reverse nd [RS-EPT-CBR] [3]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195

 [2] Ren D., Bedzyk LA., Thomas SM., Ye RW., Wood TK., 2004, Gene expression in Escherichia coli biofilms., Appl Microbiol Biotechnol 64(4):515-24

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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