RegulonDB RegulonDB 10.8: Gene Form
   

rsxC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

rsxC rsxD rsxA rsxB TSS_1909 TSS_1909 TSS_1908 TSS_1908

Gene      
Name: rsxC    Texpresso search in the literature
Synonym(s): ECK1625, G6873, b1629, ydgN
Genome position(nucleotides): 1706919 --> 1709141 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 55.38
External database links:  
ASAP:
 ABE-0005454
ECHOBASE:
 EB3694
OU-MICROARRAY:
 b1629
PortEco:
 rsxC
STRING:
 511145.b1629
COLOMBOS: rsxC


Product      
Name: SoxR [2Fe-2S] reducing system protein RsxC
Synonym(s): RsxC, YdgN, member of SoxR-reducing complex
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 80.172
Isoelectric point: 8.829
Motif(s):
 
Type Positions Sequence
369 -> 397 GEPQEEQSCIRCSACADACPADLLPQQLY
407 -> 436 KATTHNIADCIECGACAWVCPSNIPLVQYF
139 -> 283 IHQFGVAGLGGAGFPTGVKLQGGGDKIETLIINAAECEPYITADDRLMQDCAAQVVEGIRILAHILQPREILIGIEDNKPQAISMLRAVLADSNDISLRVIPTKYPSGGAKQLTYILTGKQVPHGGRSSDIGVLMQNVGTAYAVK
376 -> 430 SCIRCSACADACPADLLPQQLYWFSKGQQHDKATTHNIADCIECGACAWVCPSNI
296 -> 344 VVTLTGEAIARPGNVWARLGTPVRHLLNDAGFCPSADQMVIMGGPLMGF

 
Classification:
Multifun Terms (GenProtEC)  
  3 - regulation --> 3.1 - type of regulation --> 3.1.3 - posttranscriptional
  5 - cell processes --> 5.5 - adaptations --> 5.5.6 - other (mechanical, nutritional, oxidative stress)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
molecular_function GO:0009055 - electron transfer activity
GO:0046872 - metal ion binding
GO:0051536 - iron-sulfur cluster binding
GO:0051539 - 4 iron, 4 sulfur cluster binding
biological_process GO:0022900 - electron transport chain
GO:0055114 - oxidation-reduction process
Note(s): Note(s): ...[more].
Evidence: [IFC] Inferred by functional complementation
[IHBCE] Inferred by a human based on computational evidence
Reference(s): [1] Koo MS., et al., 2003
External database links:  
DIP:
 DIP-28084N
ECOCYC:
 G6873-MONOMER
ECOLIWIKI:
 b1629
INTERPRO:
 IPR017900
INTERPRO:
 IPR037225
INTERPRO:
 IPR026902
INTERPRO:
 IPR019554
INTERPRO:
 IPR017896
INTERPRO:
 IPR011538
INTERPRO:
 IPR010208
INTERPRO:
 IPR009051
MODBASE:
 P77611
PANTHER:
 PTHR43034
PFAM:
 PF12838
PFAM:
 PF01512
PFAM:
 PF10531
PFAM:
 PF13375
PRIDE:
 P77611
PRODB:
 PRO_000023792
PROSITE:
 PS51379
PROSITE:
 PS00198
REFSEQ:
 NP_416146
SMR:
 P77611
UNIPROT:
 P77611


Operon      
Name: ydgK-rsxABCDGE-nth         
Operon arrangement:
Transcription unit        Promoter
ydgK-rsxABCDGE-nth
rsxABCDGE-nth


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1908 1706717 forward nd [RS-EPT-CBR] [2]
  promoter TSS_1909 1708484 reverse nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Koo MS., Lee JH., Rah SY., Yeo WS., Lee JW., Lee KL., Koh YS., Kang SO., Roe JH., 2003, A reducing system of the superoxide sensor SoxR in Escherichia coli., EMBO J 22(11):2614-22

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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