RegulonDB RegulonDB 10.8: Gene Form
   

anmK gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

anmK slyB mliC PhoP TSS_1926 TSS_1926 TSS_1925 TSS_1925 TSS_1924 TSS_1924 TSS_1923 TSS_1923 TSS_1922 TSS_1922 TSS_1921 TSS_1921 slyBp1 slyBp1 TSS_1919 TSS_1919 TSS_1918 (cluster) TSS_1918 (cluster) slyBp2 slyBp2 anmKp9 anmKp9 TSS_1917 (cluster) TSS_1917 (cluster)

Gene      
Name: anmK    Texpresso search in the literature
Synonym(s): ECK1636, G6880, b1640, ydhH
Genome position(nucleotides): 1718493 <-- 1719602 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 54.59
External database links:  
ASAP:
 ABE-0005488
ECHOBASE:
 EB3700
OU-MICROARRAY:
 b1640
PortEco:
 anmK
STRING:
 511145.b1640
COLOMBOS: anmK


Product      
Name: anhydro-N-acetylmuramic acid kinase
Synonym(s): AnmK, YdhH
Sequence: Get amino acid sequence Fasta Format
Molecular weight: 39.496
Isoelectric point: 6.033
Motif(s):
 
Type Positions Sequence
5 -> 367 RFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSLKQAVLDICQGQQLTLSQFGQLDTQLGQLFADAVNALLKEQNLQARDIVAIGCHGQTVWHEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPTERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGKVILPLLQNMLSDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAVTISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASQETVLGAIFPA
12 -> 19 GTSLDGVD

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.7 - central intermediary metabolism --> 1.7.34 - murein turnover, recycling
Gene Ontology Terms (GO)  
molecular_function GO:0016740 - transferase activity
GO:0016301 - kinase activity
GO:0016773 - phosphotransferase activity, alcohol group as acceptor
GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
biological_process GO:0005975 - carbohydrate metabolic process
GO:0006040 - amino sugar metabolic process
GO:0009254 - peptidoglycan turnover
GO:0016310 - phosphorylation
GO:0097175 - 1,6-anhydro-N-acetyl-beta-muramic acid catabolic process
Note(s): Note(s): ...[more].
Reference(s): [1] Baran R., et al., 2013
External database links:  
DIP:
 DIP-11731N
ECOCYC:
 G6880-MONOMER
ECOLIWIKI:
 b1640
INTERPRO:
 IPR005338
PANTHER:
 PTHR30605
PFAM:
 PF03702
PRIDE:
 P77570
PRODB:
 PRO_000022102
REFSEQ:
 NP_416157
SMR:
 P77570
UNIPROT:
 P77570


Operon      
Name: anmK         
Operon arrangement:
Transcription unit        Promoter
 


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1917 (cluster) 1719631 reverse For this promoter, there
Read more > 		[RS-EPT-CBR] [2]
  promoter anmKp9 1719673 reverse Similarity to the consensus
Read more > 		[ICWHO] [3]
  promoter TSS_1918 (cluster) 1719751 forward For this promoter, there
Read more > 		[RS-EPT-CBR] [2]
  promoter TSS_1919 1719770 forward nd [RS-EPT-CBR] [2]
  promoter TSS_1921 1719780 forward nd [RS-EPT-CBR] [2]
  promoter TSS_1922 1719799 forward nd [RS-EPT-CBR] [2]
  promoter TSS_1923 1719807 forward nd [RS-EPT-CBR] [2]
  promoter TSS_1924 1719829 forward nd [RS-EPT-CBR] [2]
  promoter TSS_1925 1719831 forward nd [RS-EPT-CBR] [2]
  promoter TSS_1926 1720091 forward nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [ICWHO] Inferred computationally without human oversight


Reference(s)    

 [1] Baran R., Bowen BP., Price MN., Arkin AP., Deutschbauer AM., Northen TR., 2013, Metabolic footprinting of mutant libraries to map metabolite utilization to genotype., ACS Chem Biol 8(1):189-99

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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