RegulonDB RegulonDB 10.10: Gene Form
   

yegS gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yegS yegR insE5 insEF5 unknown insF5 EvgA yegSp8 yegSp8 yegSp7 yegSp7 yegSp5 yegSp5 yegSp6 yegSp6 yegRp yegRp

Gene      
Name: yegS    Texpresso search in the literature
Synonym(s): ECK2082, G7123, b2086
Genome position(nucleotides): 2168712 --> 2169611 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 49.67
External database links:  
ASAP:
 ABE-0006911
ECHOBASE:
 EB4111
ECOLIHUB:
 yegS
OU-MICROARRAY:
 b2086
STRING:
 511145.b2086
COLOMBOS: yegS


Product      
Name: lipid kinase YegS
Synonym(s): YegS
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 32.039
Isoelectric point: 4.418
Motif(s):
 
Type Positions Sequence
8 -> 129 LLILNGKSTDNLPLREAIMLLREEGMTIHVRVTWEKGDAARYVEEARKFGVATVIAGGGDGTINEVSTALIQCEGDDIPALGILPLGTANDFATSVGIPEALDKALKLAIAGDAIAIDMAQV
2 -> 133 AEFPASLLILNGKSTDNLPLREAIMLLREEGMTIHVRVTWEKGDAARYVEEARKFGVATVIAGGGDGTINEVSTALIQCEGDDIPALGILPLGTANDFATSVGIPEALDKALKLAIAGDAIAIDMAQVNKQT
66 -> 72 GDGTINE

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0005515 - protein binding
GO:0016740 - transferase activity
GO:0046872 - metal ion binding
GO:0016301 - kinase activity
GO:0001727 - lipid kinase activity
GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0003951 - NAD+ kinase activity
GO:0000287 - magnesium ion binding
biological_process GO:0006629 - lipid metabolic process
GO:0008654 - phospholipid biosynthetic process
GO:0016310 - phosphorylation
GO:0046834 - lipid phosphorylation
Note(s): Note(s): ...[more].
Reference(s): [1] Maharjan RP., et al., 2013
External database links:  
DIP:
 DIP-11889N
DISPROT:
 DP01981
ECOCYC:
 G7123-MONOMER
ECOLIWIKI:
 b2086
INTERPRO:
 IPR022433
INTERPRO:
 IPR016064
INTERPRO:
 IPR005218
INTERPRO:
 IPR001206
INTERPRO:
 IPR017438
PDB:
 2BON
PDB:
 2JGR
PFAM:
 PF00781
PRIDE:
 P76407
PROSITE:
 PS50146
REFSEQ:
 NP_416590
SMART:
 SM00046
SMR:
 P76407
UNIPROT:
 P76407


Operon      
Name: yegS         
Operon arrangement:
Transcription unit        Promoter
yegS


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yegSp6 2168543 forward nd [ICWHO] [2]
  promoter yegSp5 2168558 forward nd [ICWHO] [2]
  promoter yegSp7 2168565 forward nd [ICWHO] [2]
  promoter yegSp8 2168683 forward nd [ICWHO] [2]


Evidence    

 [ICWHO] Inferred computationally without human oversight


Reference(s)    

 [1] Maharjan RP., Gaffe J., Plucain J., Schliep M., Wang L., Feng L., Tenaillon O., Ferenci T., Schneider D., 2013, A case of adaptation through a mutation in a tandem duplication during experimental evolution in Escherichia coli., BMC Genomics 14:441

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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