RegulonDB RegulonDB 10.10: Gene Form
   

fbaB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yegT fbaB gatY yegU Cra CRP terminator yegTp yegTp fbaBp fbaBp gatYp gatYp TSS_2434 TSS_2434 TSS_2433 TSS_2433 TSS_2432 TSS_2432 TSS_2431 TSS_2431 TSS_2430 TSS_2430 TSS_2429 TSS_2429 TSS_2428 TSS_2428 TSS_2427 TSS_2427 TSS_2426 TSS_2426 TSS_2425 TSS_2425 TSS_2424 TSS_2424 TSS_2423 TSS_2423 TSS_2422 TSS_2422 TSS_2421 (cluster) TSS_2421 (cluster) gatZp gatZp TSS_2419 (cluster) TSS_2419 (cluster)

Gene      
Name: fbaB    Texpresso search in the literature
Synonym(s): ECK2090, G7129, b2097, dhnA
Genome position(nucleotides): 2177512 <-- 2178564 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 51.19
External database links:  
ASAP:
 ABE-0006941
ECHOBASE:
 EB3815
ECOLIHUB:
 fbaB
OU-MICROARRAY:
 b2097
STRING:
 511145.b2097
COLOMBOS: fbaB


Product      
Name: fructose-bisphosphate aldolase class I
Synonym(s): DhnA, FbaB
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol,membrane
Molecular weight: 38.109
Isoelectric point: 6.722
Motif(s):
 
Type Positions Sequence
69 -> 326 SILPVDQGVEHSAGASFAANPLYFDPKNIVELAIEAGCNCVASTYGVLASVSRRYAHRIPFLVKLNHNETLSYPNTYDQTLYASVEQAFNMGAVAVGATIYFGSEESRRQIEEISAAFERAHELGMVTVLWAYLRNSAFKKDGVDYHVSADLTGQANHLAATIGADIVKQKMAENNGGYKAINYGYTDDRVYSKLTSENPIDLVRYQLANCYMGRAGLINSGGAAGGETDLSDAVRTAVINKRAGGMGLILGRKAFKK
239 -> 239 K
2 -> 350 TDIAQLLGKDADNLLQHRCMTIPSDQLYLPGHDYVDRVMIDNNRPPAVLRNMQTLYNTGRLAGTGYLSILPVDQGVEHSAGASFAANPLYFDPKNIVELAIEAGCNCVASTYGVLASVSRRYAHRIPFLVKLNHNETLSYPNTYDQTLYASVEQAFNMGAVAVGATIYFGSEESRRQIEEISAAFERAHELGMVTVLWAYLRNSAFKKDGVDYHVSADLTGQANHLAATIGADIVKQKMAENNGGYKAINYGYTDDRVYSKLTSENPIDLVRYQLANCYMGRAGLINSGGAAGGETDLSDAVRTAVINKRAGGMGLILGRKAFKKSMADGVKLINAVQDVYLDSKITIA
192 -> 192 L
237 -> 237 K

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.3 - energy metabolism, carbon --> 1.3.1 - glycolysis
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016020 - membrane
molecular_function GO:0003824 - catalytic activity
GO:0005515 - protein binding
GO:0016829 - lyase activity
GO:0004332 - fructose-bisphosphate aldolase activity
GO:0042802 - identical protein binding
biological_process GO:0006096 - glycolytic process
External database links:  
DIP:
 DIP-36197N
ECOCYC:
 FRUCBISALD-CLASSI-MONOMER
ECOLIWIKI:
 b2097
INTERPRO:
 IPR041720
INTERPRO:
 IPR013785
INTERPRO:
 IPR002915
MODBASE:
 P0A991
PFAM:
 PF01791
PRIDE:
 P0A991
PRODB:
 PRO_000022575
REFSEQ:
 NP_416600
SMART:
 SM01133
UNIPROT:
 P0A991


Operon      
Name: fbaB         
Operon arrangement:
Transcription unit        Promoter
fbaB


Transcriptional Regulation      
Display Regulation             
Repressed by: Cra


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2419 (cluster) 2176382 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2421 (cluster) 2176636 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2422 2176657 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2423 2176773 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2424 2176779 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2425 2176864 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2426 2177023 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2427 2177046 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2428 2177069 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2429 2177071 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2430 2177123 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2431 2177200 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2432 2177204 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2433 2177212 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2434 2177228 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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