RegulonDB RegulonDB 10.10: Gene Form
   

rcnA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

rcnA rcnB rcnR Fur Fur Fur RcnR RcnR rcnBp rcnBp rcnRp rcnRp rcnAp rcnAp

Gene      
Name: rcnA    Texpresso search in the literature
Synonym(s): ECK2099, G7138, b2106, yohM
Genome position(nucleotides): 2185917 --> 2186741 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 51.52
External database links:  
ASAP:
 ABE-0006968
ECHOBASE:
 EB3824
ECOLIHUB:
 rcnA
OU-MICROARRAY:
 b2106
STRING:
 511145.b2106
COLOMBOS: rcnA


Product      
Name: Ni2+/Co2+ exporter
Synonym(s): RcnA, YohM
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 30.419
Isoelectric point: 9.165
Motif(s):
 
Type Positions Sequence
57 -> 77 LAATISHTAVVWLIAFGGMVI
176 -> 196 LLFGLTGGLIPCPAAITVLLI
87 -> 107 EPWLQLISAVIIISTAFWMFW
13 -> 33 AWFFIPSAILLGALHGLEPGH
252 -> 272 FSSLLIGLVGVYMGVHGFMGI

 
Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.9.A - Transporters of Unknown Classification
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015099 - nickel cation transmembrane transporter activity
GO:0046583 - cation efflux transmembrane transporter activity
biological_process GO:0006811 - ion transport
GO:0006824 - cobalt ion transport
GO:0015675 - nickel cation transport
GO:0010045 - response to nickel cation
GO:0032025 - response to cobalt ion
GO:0035444 - nickel cation transmembrane transport
GO:0035784 - nickel cation homeostasis
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
 G7138-MONOMER
ECOLIWIKI:
 b2106
INTERPRO:
 IPR011541
PFAM:
 PF03824
PRIDE:
 P76425
PRODB:
 PRO_000023687
REFSEQ:
 NP_416609
UNIPROT:
 P76425


Operon      
Name: rcnAB         
Operon arrangement:
Transcription unit        Promoter
rcnAB
rcnB


Transcriptional Regulation      
Display Regulation             
Repressed by: Fur, RcnR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter rcnBp 2186884 forward nd [ICWHO] [1]


Evidence    

 [ICWHO] Inferred computationally without human oversight


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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