RegulonDB RegulonDB 10.8: Gene Form
   

hxpA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yfbS hxpA yfbU anti-anti-terminator anti-terminator terminator yfbUp yfbUp TSS_2581 TSS_2581 TSS_2580 TSS_2580 TSS_2579 TSS_2579 TSS_2578 (cluster) TSS_2578 (cluster) TSS_2577 TSS_2577 TSS_2576 TSS_2576 TSS_2575 (cluster) TSS_2575 (cluster) TSS_2574 TSS_2574 TSS_2573 (cluster) TSS_2573 (cluster) TSS_2572 TSS_2572 TSS_2571 TSS_2571 TSS_2570 (cluster) TSS_2570 (cluster)

Gene      
Name: hxpA    Texpresso search in the literature
Synonym(s): ECK2287, G7187, b2293, yfbT
Genome position(nucleotides): 2411439 <-- 2412089 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 56.53
External database links:  
ASAP:
 ABE-0007567
ECHOBASE:
 EB3857
OU-MICROARRAY:
 b2293
PortEco:
 yfbT
STRING:
 511145.b2293
COLOMBOS: hxpA


Product      
Name: hexitol phosphatase A
Synonym(s): HAD2, HxpA, YfbT, sugar phosphatase YfbT
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 23.007
Isoelectric point: 6.084
Motif(s):
 
Type Positions Sequence
9 -> 11 DLD
7 -> 181 LFDLDGTLVDSLPAVERAWSNWARRHGLAPEEVLAFIHGKQAITSLRHFMAGKSEADIAAEFTRLEHIEATETEGITALPGAIALLSHLNKAGIPWAIVTSGSMPVARARHKIAGLPAPEVFVTAERVKRGKPEPDAYLLGAQLLGLAPQECVVVEDAPAGVLSGLAAGCHVIAV
106 -> 107 TS

 
Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0050286 - sorbitol-6-phosphatase activity
GO:0050084 - mannitol-1-phosphatase activity
GO:0016787 - hydrolase activity
GO:0046872 - metal ion binding
GO:0016791 - phosphatase activity
GO:0050308 - sugar-phosphatase activity
GO:0000287 - magnesium ion binding
GO:0030145 - manganese ion binding
GO:0050897 - cobalt ion binding
GO:0043136 - glycerol-3-phosphatase activity
biological_process GO:0005975 - carbohydrate metabolic process
GO:0016311 - dephosphorylation
Note(s): Note(s): ...[more].
External database links:  
DIP:
 DIP-11972N
ECOCYC:
 G7187-MONOMER
ECOLIWIKI:
 b2293
INTERPRO:
 IPR023198
INTERPRO:
 IPR041492
INTERPRO:
 IPR036412
INTERPRO:
 IPR006439
INTERPRO:
 IPR023214
MINT:
 MINT-1275778
MODBASE:
 P77625
PFAM:
 PF13419
PRIDE:
 P77625
PRINTS:
 PR00413
REFSEQ:
 NP_416796
SMR:
 P77625
UNIPROT:
 P77625


Operon      
Name: yfbU-hxpA         
Operon arrangement:
Transcription unit        Promoter
yfbU-hxpA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2570 (cluster) 2409942 reverse For this promoter, there
Read more > 		[RS-EPT-CBR] [1]
  promoter TSS_2571 2409945 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2572 2409947 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2573 (cluster) 2409960 reverse For this promoter, there
Read more > 		[RS-EPT-CBR] [1]
  promoter TSS_2574 2410159 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2575 (cluster) 2410629 reverse For this promoter, there
Read more > 		[RS-EPT-CBR] [1]
  promoter TSS_2576 2410812 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2577 2410818 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2578 (cluster) 2411098 reverse For this promoter, there
Read more > 		[RS-EPT-CBR] [1]
  promoter TSS_2579 2411731 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2580 2411792 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2581 2412114 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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