RegulonDB RegulonDB 10.9: Gene Form
   

yfcJ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

fabB yfcJ pdxB flk anti-anti-terminator anti-terminator terminator TSS_2635 TSS_2635 TSS_2634 TSS_2634 TSS_2633 TSS_2633 TSS_2632 TSS_2632 TSS_2631 TSS_2631 TSS_2630 (cluster) TSS_2630 (cluster) yfcJp2 yfcJp2 TSS_2628 TSS_2628 flKp flKp pdxBp pdxBp TSS_2627 TSS_2627 TSS_2626 TSS_2626 usgp usgp

Gene      
Name: yfcJ    Texpresso search in the literature
Synonym(s): ECK2316, G7198, b2322
Genome position(nucleotides): 2438942 <-- 2440120 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
56.57
External database links:  
ASAP:
ABE-0007669
ECHOBASE:
EB3866
ECOLIHUB:
yfcJ
OU-MICROARRAY:
b2322
STRING:
511145.b2322
COLOMBOS: yfcJ


Product      
Name: putative transporter YfcJ
Synonym(s): YfcJ
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 40.465
Isoelectric point: 10.555
Motif(s):
 
Type Positions Sequence
83 -> 105 SALQGMLACGLAGGALLLAAILP
176 -> 198 GFAALAITTMVLPVLAWACNGTV
370 -> 389 VFLAGAISAVLGIIVTILSF
120 -> 142 LILGFGESQLLTGALTWGLGIVG
247 -> 269 GWAMAGFTLTAFGGAFVVMRVMF

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0022857 - transmembrane transporter activity
biological_process GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Jindal S., et al., 2019
External database links:  
ECOCYC:
B2322-MONOMER
ECOLIWIKI:
b2322
INTERPRO:
IPR036259
INTERPRO:
IPR020846
INTERPRO:
IPR011701
INTERPRO:
IPR037541
MODBASE:
P77549
PFAM:
PF07690
PRIDE:
P77549
PROSITE:
PS50850
REFSEQ:
NP_416825
UNIPROT:
P77549


Operon      
Name: yfcJ         
Operon arrangement:
Transcription unit        Promoter
yfcJ


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2626 2437519 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2627 2437883 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2628 2440231 reverse nd [RS-EPT-CBR] [2]
  promoter yfcJp2 2440241 reverse Similarity to the consensus
Read more >
[ICWHO], [RS-EPT-CBR] [2], [3]
  promoter TSS_2630 (cluster) 2440572 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [2]
  promoter TSS_2631 2440574 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2632 2440576 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2633 2440845 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2634 2440847 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2635 2441152 reverse nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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