RegulonDB RegulonDB 10.7: Gene Form
   

mlaA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yfdF yfdC mlaA Fis mlaAp mlaAp

Gene      
Name: mlaA    Texpresso search in the literature
Synonym(s): ECK2340, G7216, b2346, vacJ
Genome position(nucleotides): 2464252 <-- 2465007 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
51.85
External database links:  
ASAP:
ABE-0007745
ECHOBASE:
EB4024
OU-MICROARRAY:
b2346
PORTECO:
mlaA
REGULONDB:
b2346
STRING:
511145.b2346
M3D: mlaA
COLOMBOS: mlaA
PortEco: b2346


Product      
Name: intermembrane phospholipid transport system - outer membrane lipoprotein MlaA
Synonym(s): MlaA, VacJ
Sequence: Get amino acid sequence Fasta Format
Cellular location: outer membrane
Molecular weight: 28.042
Isoelectric point: 4.647
Motif(s):
 
Type Positions Sequence
1 -> 4 MKLR
29 -> 222 SDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADGFYPVLSWLTWPMSVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHD
18 -> 251 CASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADGFYPVLSWLTWPMSVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQAIQDDLKDIDSE
41 -> 42 NF

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport
Gene Ontology Terms (GO)  
cellular_component GO:0009279 - cell outer membrane
GO:0016020 - membrane
molecular_function GO:0005515 - protein binding
biological_process GO:0120010 - intermembrane phospholipid transfer
Note(s): Note(s): ...[more].
Reference(s): [1] Abellon-Ruiz J., et al., 2017
[2] Ishihama Y., et al., 2008
External database links:  
ECOCYC:
G7216-MONOMER
ECOLIWIKI:
b2346
INTERPRO:
IPR007428
PANTHER:
PTHR30035
PFAM:
PF04333
PRIDE:
P76506
PRINTS:
PR01805
PRODB:
PRO_000024209
PROSITE:
PS51257
PROTEINMODELPORTAL:
P76506
REFSEQ:
NP_416848
SMR:
P76506
UNIPROT:
P76506


Operon      
Name: mlaA         
Operon arrangement:
Transcription unit        Promoter
mlaA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Abellon-Ruiz J., Kaptan SS., Basle A., Claudi B., Bumann D., Kleinekathofer U., van den Berg B., 2017, Structural basis for maintenance of bacterial outer membrane lipid asymmetry., Nat Microbiol 2(12):1616-1623

 [2] Ishihama Y., Schmidt T., Rappsilber J., Mann M., Hartl FU., Kerner MJ., Frishman D., 2008, Protein abundance profiling of the Escherichia coli cytosol., BMC Genomics 9:102


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