RegulonDB RegulonDB 10.6.3: Gene Form
   

hyfE gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

hyfF hyfD hyfE hyfG

Gene      
Name: hyfE    Texpresso search in the literature
Synonym(s): ECK2481, G7302, b2485
Genome position(nucleotides): 2606262 --> 2606912 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
53.3
Reference(s): [1] Andrews SC., et al., 1997
External database links:  
ASAP:
ABE-0008188
ECHOBASE:
EB3965
ECOCYC:
G7302
ECOLIHUB:
hyfE
OU-MICROARRAY:
b2485
REGULONDB:
b2485
STRING:
511145.b2485
M3D: hyfE
COLOMBOS: hyfE
PortEco: b2485


Product      
Name: hydrogenase 4 component E
Synonym(s): HyfE
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 23.361
Isoelectric point: 9.37
Motif(s):
 
Type Positions Sequence
123 -> 143 GLKPALAVALGHFLLGLLCIV
176 -> 196 LVEIGIATDAIFAVIVMVLLA
151 -> 171 QIFGYCLMENGSHLVLALLAW
39 -> 59 LVLVSIFATLSCLFAAEQLLI
93 -> 113 FGPAMMALLAALIVLLCAFVV

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.3 - energy metabolism, carbon --> 1.3.7 - anaerobic respiration
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0016491 - oxidoreductase activity
biological_process GO:0055114 - oxidation-reduction process
Reference(s): [1] Andrews SC., et al., 1997
External database links:  
DIP:
DIP-48020N
ECOCYC:
MONOMER0-142
ECOLIWIKI:
b2485
INTERPRO:
IPR038730
INTERPRO:
IPR039428
MINT:
MINT-1289177
PANTHER:
PTHR38601
PFAM:
PF00420
PRIDE:
P0AEW1
PRODB:
PRO_000022967
PROTEINMODELPORTAL:
P0AEW1
REFSEQ:
NP_416980
SMR:
P0AEW1
UNIPROT:
P0AEW1


Operon      
Name: hyfABCDEFGHIJR-focB         
Operon arrangement:
Transcription unit        Promoter
hyfABCDEFGHIJR-focB


Transcriptional Regulation      
Display Regulation             
Activated by: FhlA, CRP, HyfR
Repressed by: FNR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Andrews SC., Berks BC., McClay J., Ambler A., Quail MA., Golby P., Guest JR., 1997, A 12-cistron Escherichia coli operon (hyf) encoding a putative proton-translocating formate hydrogenlyase system., Microbiology 143 ( Pt 11):3633-47


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