RegulonDB RegulonDB 10.6.3: Gene Form
   

hyfI gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

hyfR hyfG hyfI hyfH hyfJ hyfF

Gene      
Name: hyfI    Texpresso search in the literature
Synonym(s): ECK2485, G7306, b2489
Genome position(nucleotides): 2610706 --> 2611464 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
55.73
Reference(s): [1] Andrews SC., et al., 1997
External database links:  
ASAP:
ABE-0008198
ECHOBASE:
EB3969
ECOCYC:
G7306
ECOLIHUB:
hyfI
OU-MICROARRAY:
b2489
REGULONDB:
b2489
STRING:
511145.b2489
M3D: hyfI
COLOMBOS: hyfI
PortEco: b2489


Product      
Name: hydrogenase 4 catalytic subunit HyfI
Synonym(s): HyfI, hydrogenase 4, small subunit
Sequence: Get amino acid sequence Fasta Format
Molecular weight: 28.101
Isoelectric point: 8.083
Motif(s):
 
Type Positions Sequence
44 -> 151 CNACEIEIFAAITPVFDAERFGIKVVSSPRHADILLFTGAVTRAMRMPALRAYESAPDHKICVSYGACGVGGGIFHDLYSVWGGSDTIVPIDVWIPGCPPTPAATIHG

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.3 - energy metabolism, carbon --> 1.3.7 - anaerobic respiration
Gene Ontology Terms (GO)  
molecular_function GO:0046872 - metal ion binding
GO:0016491 - oxidoreductase activity
GO:0051536 - iron-sulfur cluster binding
GO:0051539 - 4 iron, 4 sulfur cluster binding
GO:0008137 - NADH dehydrogenase (ubiquinone) activity
GO:0048038 - quinone binding
biological_process GO:0055114 - oxidation-reduction process
Note(s): Note(s): ...[more].
Reference(s): [1] Andrews SC., et al., 1997
External database links:  
ECOCYC:
MONOMER0-151
ECOLIWIKI:
b2489
INTERPRO:
IPR006138
INTERPRO:
IPR006137
MODBASE:
P77668
PANTHER:
PTHR11995
PFAM:
PF01058
PRIDE:
P77668
PROSITE:
PS01150
PROTEINMODELPORTAL:
P77668
REFSEQ:
NP_416984
SMR:
P77668
UNIPROT:
P77668


Operon      
Name: hyfABCDEFGHIJR-focB         
Operon arrangement:
Transcription unit        Promoter
hyfABCDEFGHIJR-focB


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, FhlA, HyfR
Repressed by: FNR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Andrews SC., Berks BC., McClay J., Ambler A., Quail MA., Golby P., Guest JR., 1997, A 12-cistron Escherichia coli operon (hyf) encoding a putative proton-translocating formate hydrogenlyase system., Microbiology 143 ( Pt 11):3633-47


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