RegulonDB RegulonDB 11.0: Gene Form
   

ygaH gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

ygaY ygaZ mprA ygaH MprA anti-terminator anti-anti-terminator mprAp mprAp TSS_2995 TSS_2995 TSS_2994 TSS_2994 ygaZp8 ygaZp8 TSS_2993 TSS_2993

Gene      
Name: ygaH    Texpresso search in the literature
Synonym(s): ECK2677, G7406, b2683
Genome position(nucleotides): 2810344 --> 2810679
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 54.46
External database links:  
ASAP:
 ABE-0008831
ECHOBASE:
 EB2775
ECOLIHUB:
 ygaH
OU-MICROARRAY:
 b2683
STRING:
 511145.b2683
COLOMBOS: ygaH


Product      
Name: L-valine exporter, YgaH component
Synonym(s): YgaH
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 12.024
Isoelectric point: 10.35
Motif(s):
 
Type Positions Sequence Comment
5 -> 104 VLLLGLLVGVANYCFRYLPLRLRVGNARPTKRGAVGILLDTIGIASICALLVVSTAPEVMHDTRRFVPTLVGFAVLGASFYKTRSIIIPTLLSALAYGLA
48 -> 49 IA UniProt: In Ref. 4..
54 -> 54 L UniProt: In Ref. 4..
89 -> 111 SIIIPTLLSALAYGLAWKVMAII UniProt: In Ref. 4..

 
Classification:
Multifun Terms (GenProtEC)  
  4 - transport
Gene Ontology Terms (GO)  
cellular_component GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:1902495 - transmembrane transporter complex
biological_process GO:1903785 - L-valine transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Jindal S., et al., 2019
External database links:  
ALPHAFOLD:
 P43667
ECOCYC:
 G7406-MONOMER
ECOLIWIKI:
 b2683
INTERPRO:
 IPR008407
PFAM:
 PF05437
PRIDE:
 P43667
REFSEQ:
 NP_417168
UNIPROT:
 P43667


Operon      
Name: ygaZH         
Operon arrangement:
Transcription unit        Promoter
ygaZH


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2993 2809569 forward nd [RS-EPT-CBR] [2]
  promoter ygaZp8 2809595 forward nd [ICWHO] [3]
  promoter TSS_2994 2809748 forward nd [RS-EPT-CBR] [2]
  promoter TSS_2995 2809756 forward nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [ICWHO] Inferred computationally without human oversight


Reference(s)    

 [1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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