RegulonDB RegulonDB 10.8: Gene Form
   

casD gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

casC cas1 casD casE ygbFp ygbFp

Gene      
Name: casD    Texpresso search in the literature
Synonym(s): ECK2752, G7427, b2757, cas5e, ygcI
Genome position(nucleotides): 2880374 <-- 2881048 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
48.15
External database links:  
ASAP:
ABE-0009044
ECHOBASE:
EB2917
OU-MICROARRAY:
b2757
PortEco:
casD
STRING:
511145.b2757
COLOMBOS: casD


Product      
Name: type I-E CRISPR system Cascade subunit CasD
Synonym(s): Cas5e, CasD, Cascade subunit D, YgcI
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 25.209
Isoelectric point: 7.497
Motif(s):
 
Type Positions Sequence
4 -> 179 YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG

 

Classification:
Multifun Terms (GenProtEC)  
  5 - cell processes --> 5.10 - defense/survival
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0032991 - protein-containing complex
molecular_function GO:0005515 - protein binding
GO:0003723 - RNA binding
GO:0071667 - DNA/RNA hybrid binding
biological_process GO:0051607 - defense response to virus
GO:0043571 - maintenance of CRISPR repeat elements
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-12125N
ECOCYC:
G7427-MONOMER
ECOLIWIKI:
b2757
INTERPRO:
IPR013422
INTERPRO:
IPR010147
INTERPRO:
IPR021124
PDB:
5H9F
PDB:
5CD4
PDB:
4U7U
PDB:
4TVX
PDB:
4QYZ
PDB:
5H9E
PFAM:
PF09704
PRIDE:
Q46898
REFSEQ:
NP_417237
SMR:
Q46898
UNIPROT:
Q46898


Operon      
Name: casABCDE12         
Operon arrangement:
Transcription unit        Promoter
ygbF
casABCDE12
casDE-ygbTF


Transcriptional Regulation      
Display Regulation             
Activated by: SlyA, LeuO
Repressed by: CRP, H-NS


Regulation by small RNA    
  Display Regulation
small RNA gcvB


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



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