RegulonDB RegulonDB 11.1: Gene Form
   

kbaZ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

kbaZ agaR agaV AgaR AgaR CRP AgaR AgaR AgaR kbaZp kbaZp TSS_3412 (cluster) TSS_3412 (cluster) agaRp agaRp TSS_3411 TSS_3411 TSS_3410 (cluster) TSS_3410 (cluster)

Gene      
Name: kbaZ    Texpresso search in the literature
Synonym(s): ECK3120, G7631, agaZ, b3132, yhaX
Genome position(nucleotides): 3278914 --> 3280194
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 55.27
External database links:  
ASAP:
 ABE-0010295
ECHOBASE:
 EB2616
ECOLIHUB:
 kbaZ
OU-MICROARRAY:
 b3132
STRING:
 511145.b3132
COLOMBOS: kbaZ


Product      
Name: putative tagatose-1,6-bisphosphate aldolase 1 chaperone
Synonym(s): AgaZ, KbaZ, YhaX
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane,cytosol
Molecular weight: 47.192
Isoelectric point: 5.041
Motif(s):
 
Type Positions Sequence Comment
4 -> 423 LTEMVRQHKAGKTNGIYAVCSAHPLVLEAAIRYASANQTPLLIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPAAQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCLEHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWPRIIALVVQPGVEFDHTNVIDYQPAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLVIDHFAILKVGPALTFALREALFSLAAIEEELVPAKACSGLRQVLEDVMLDRPEYWQSHYHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQYVKVRSGELQPTPRELIINHIQDILAQYHTAC

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0005887 - integral component of plasma membrane
GO:1902494 - catalytic complex
molecular_function GO:0003824 - catalytic activity
GO:0008047 - enzyme activator activity
biological_process GO:0005975 - carbohydrate metabolic process
GO:0009401 - phosphoenolpyruvate-dependent sugar phosphotransferase system
GO:0050790 - regulation of catalytic activity
GO:2001059 - D-tagatose 6-phosphate catabolic process
Note(s): Note(s): ...[more].
Evidence: [EXP-IMP] Inferred from mutant phenotype
Reference(s): [1] Brinkkotter A., et al., 2002
External database links:  
ALPHAFOLD:
 P0C8K0
DIP:
 DIP-9075N
ECOCYC:
 G7631-MONOMER
ECOLIWIKI:
 b3132
INTERPRO:
 IPR013785
INTERPRO:
 IPR012062
INTERPRO:
 IPR023435
PFAM:
 PF08013
PRIDE:
 P0C8K0
REFSEQ:
 NP_417601
SMR:
 P0C8K0
SWISSMODEL:
 P42903
UNIPROT:
 P0C8K0


Operon      
Name: kbaZ-agaVWA         
Operon arrangement:
Transcription unit        Promoter
kbaZ-agaVWA


Transcriptional Regulation      
Display Regulation             
Activated by: CRP
Repressed by: AgaR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_3410 (cluster) 3278324 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_3411 3278701 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_3412 (cluster) 3278705 reverse nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Brinkkotter A., Shakeri-Garakani A., Lengeler JW., 2002, Two class II D-tagatose-bisphosphate aldolases from enteric bacteria., Arch Microbiol 177(5):410-9

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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