RegulonDB RegulonDB 11.1: Gene Form
   

agaS gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

agaS kbaY agaA agaV agaW AgaR AgaR AgaR AgaR AgaR AgaR agaSp agaSp

Gene      
Name: agaS    Texpresso search in the literature
Synonym(s): ECK3124, G7634, b3136, yraB
Genome position(nucleotides): 3281976 --> 3283130
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 56.62
External database links:  
ASAP:
 ABE-0010305
ECHOBASE:
 EB2620
ECOLIHUB:
 agaS
OU-MICROARRAY:
 b3136
STRING:
 511145.b3136
COLOMBOS: agaS


Product      
Name: putative galactosamine-6-phosphate deaminase/isomerase
Synonym(s): AgaS, YraB
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane,cytosol
Molecular weight: 41.783
Isoelectric point: 5.334
Motif(s):
 
Type Positions Sequence Comment
45 -> 197 LEPLLRKENLRIILTGAGTSAFIGDIIAPWLASHTGKNFSAVPTTDLVTNPMDYLNPAHPLLLISFGRSGNSPESVAAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFALLMPAETHDRGFAMTSSITTMMASCLAVFAPETINSQTF UniProt: SIS 1.
48 -> 188 LLRKENLRIILTGAGTSAFIGDIIAPWLASHTGKNFSAVPTTDLVTNPMDYLNPAHPLLLISFGRSGNSPESVAAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFALLMPAETHDRGFAMTSSITTMMASCLAVFA
215 -> 364 SEGVFGYAPWKRIVYLGSGGLQGAARESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDDETLVVVFVSSHPYTRQYDLDLLAELRRDNQAMRVIAIAAESSDIVAAGPHIILPPSRHFIDVEQAFCFLMYAQTFALMQSLHMGNTPDTP UniProt: SIS 2.
221 -> 357 YAPWKRIVYLGSGGLQGAARESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDDETLVVVFVSSHPYTRQYDLDLLAELRRDNQAMRVIAIAAESSDIVAAGPHIILPPSRHFIDVEQAFCFLMYAQTFALMQSLHM

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
molecular_function GO:0016787 - hydrolase activity
GO:0016853 - isomerase activity
GO:0097367 - carbohydrate derivative binding
GO:0043877 - galactosamine-6-phosphate isomerase activity
biological_process GO:0009401 - phosphoenolpyruvate-dependent sugar phosphotransferase system
GO:1901135 - carbohydrate derivative metabolic process
Note(s): Note(s): ...[more].
Reference(s): [1] Charbit A., et al., 1998
[2] Reizer J., et al., 1996
External database links:  
ALPHAFOLD:
 P42907
ECOCYC:
 G7634-MONOMER
ECOLIWIKI:
 b3136
INTERPRO:
 IPR035464
INTERPRO:
 IPR035466
INTERPRO:
 IPR014180
INTERPRO:
 IPR001347
MODBASE:
 P42907
PDB:
 3C3J
PFAM:
 PF01380
PRIDE:
 P42907
PROSITE:
 PS51464
REFSEQ:
 NP_417605
SMR:
 P42907
UNIPROT:
 P42907


Operon      
Name: agaS-kbaY-agaBCDI         
Operon arrangement:
Transcription unit        Promoter
agaSYBCDI


Transcriptional Regulation      
Display Regulation             
Repressed by: AgaR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Charbit A., Autret N., 1998, Horizontal transfer of chromosomal DNA between the marine bacterium Vibrio furnissii and Escherichia coli revealed by sequence analysis., Microb Comp Genomics 3(2):119-32

 [2] Reizer J., Ramseier TM., Reizer A., Charbit A., Saier MH., 1996, Novel phosphotransferase genes revealed by bacterial genome sequencing: a gene cluster encoding a putative N-acetylgalactosamine metabolic pathway in Escherichia coli., Microbiology 142 ( Pt 2):231-50

RegulonDB