RegulonDB RegulonDB 10.10: Gene Form
   

yjeH gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yjeH fxsA groS terminator anti-terminator anti-anti-terminator terminator groLp3 groLp3 TSS_4956 TSS_4956 TSS_4955 TSS_4955 groLp2 groLp2 groLp1 groLp1 TSS_4954 TSS_4954 TSS_4953 TSS_4953 TSS_4952 TSS_4952 TSS_4951 TSS_4951 groSp groSp TSS_4949 (cluster) TSS_4949 (cluster)

Gene      
Name: yjeH    Texpresso search in the literature
Synonym(s): ECK4135, G7833, b4141
Genome position(nucleotides): 4369156 <-- 4370412 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 52.27
External database links:  
ASAP:
 ABE-0013559
ECHOBASE:
 EB2363
ECOLIHUB:
 yjeH
OU-MICROARRAY:
 b4141
STRING:
 511145.b4141
COLOMBOS: yjeH


Product      
Name: L-methionine/branched chain amino acid exporter
Synonym(s): YjeH
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 44.778
Isoelectric point: 8.624
Motif(s):
 
Type Positions Sequence
379 -> 399 LLCVLLLAMVGWKSLYALIML
195 -> 195 W
258 -> 278 IVVQLFGVGALWIACVIGYLA
148 -> 168 QTVIAGLIVALIVAIWWAGDI
183 -> 203 LTGLFAALSVMFWCFVGLEAF

 
Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015179 - L-amino acid transmembrane transporter activity
GO:0022857 - transmembrane transporter activity
GO:0005294 - neutral L-amino acid secondary active transmembrane transporter activity
GO:0000102 - L-methionine secondary active transmembrane transporter activity
biological_process GO:0006865 - amino acid transport
GO:0055085 - transmembrane transport
GO:0015820 - leucine transport
GO:0015821 - methionine transport
GO:0071230 - cellular response to amino acid stimulus
GO:1903714 - isoleucine transmembrane transport
GO:1903785 - L-valine transmembrane transport
Note(s): Note(s): ...[more].
External database links:  
DIP:
 DIP-12573N
ECOCYC:
 B4141-MONOMER
ECOLIWIKI:
 b4141
INTERPRO:
 IPR002293
PFAM:
 PF13520
PRIDE:
 P39277
REFSEQ:
 NP_418565
UNIPROT:
 P39277


Operon      
Name: yjeH         
Operon arrangement:
Transcription unit        Promoter
yjeH


RNA cis-regulatory element    
Attenuation: Translational


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_4949 (cluster) 4370456 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4951 4370648 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4952 4370652 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4953 4370659 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4954 4370692 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4955 4370897 forward nd [RS-EPT-CBR] [1]
  promoter TSS_4956 4370958 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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