RegulonDB

Gene
Name:	bglJ
Synonym(s):	ECK4356, G7948, b4366, yjjR
Genome position(nucleotides):	4604160 --> 4604837 Genome Browser
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	45.28
External database links:

ASAP:	ABE-0014324
ECHOBASE:	EB2479
ECOLIHUB:	bglJ
OU-MICROARRAY:	b4366
STRING:	511145.b4366
COLOMBOS:	bglJ

Product

Name:

DNA-binding transcriptional regulator BglJ

Synonym(s):

BglJ, YjjR

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol

Molecular weight:

25.622

Isoelectric point:

9.897

Motif(s):

Type	Positions	Sequence
	152 -> 204	TLSPTEREILRFMSRGYSMTQIAEQLKRNIKTIRAHKFNVMSKLGVSSDAGLL
	170 -> 189	MTQIAEQLKRNIKTIRAHKF
	146 -> 211	YINQSRTLSPTEREILRFMSRGYSMTQIAEQLKRNIKTIRAHKFNVMSKLGVSSDAGLLEAADILL

Classification:

Multifun Terms (GenProtEC)
		1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
		2 - information transfer --> 2.2 - RNA related --> 2.2.2 - Transcription related
		3 - regulation --> 3.1 - type of regulation --> 3.1.2 - transcriptional level --> 3.1.2.2 - activator
		3 - regulation --> 3.3 - genetic unit regulated --> 3.3.1 - operon
Gene Ontology Terms (GO)
	cellular_component	GO:0005737 - cytoplasm GO:0005829 - cytosol
	molecular_function	GO:0003677 - DNA binding GO:0005515 - protein binding GO:0003700 - DNA-binding transcription factor activity
	biological_process	GO:0006355 - regulation of transcription, DNA-templated GO:0045893 - positive regulation of transcription, DNA-templated GO:0009314 - response to radiation

Note(s):

Note(s): ...[more].

Evidence:

[AIFS] Automated inference of function from sequence
[GEA] Gene expression analysis
[IMP] Inferred from mutant phenotype

Reference(s):

[1] Giel M., et al., 1996
[2] Madhusudan S., et al., 2005
[3] Perez-Rueda E., et al., 2004
[4] Sargentini NJ., et al., 2016

External database links:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

MODBASE:

PFAM:

PRIDE:

PRINTS:

PRODB:

PROSITE:

REFSEQ:

SMART:

SMR:

SWISSMODEL:

UNIPROT:

Operon

Name:

yjjQ-bglJ

Operon arrangement:

Transcription unit	Promoter
yjjQ-bglJ	yjjQp

Transcriptional Regulation
	Display Regulation
Activated by:	LeuO
Repressed by:	H-NS

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References

Reference(s)
[1] Giel M., Desnoyer M., Lopilato J., 1996, A mutation in a new gene, bglJ, activates the bgl operon in Escherichia coli K-12., Genetics 143(2):627-35
[2] Madhusudan S., Paukner A., Klingen Y., Schnetz K., 2005, Independent regulation of H-NS-mediated silencing of the bgl operon at two levels: upstream by BglJ and LeuO and downstream by DnaKJ., Microbiology 151(Pt 10):3349-59
[3] Perez-Rueda E., Collado-Vides J., Segovia L., 2004, Phylogenetic distribution of DNA-binding transcription factors in bacteria and archaea., Comput Biol Chem 28(5-6):341-50
[4] Sargentini NJ., Gularte NP., Hudman DA., 2016, Screen for genes involved in radiation survival of Escherichia coli and construction of a reference database., Mutat Res 793-794:1-14