RegulonDB RegulonDB 10.8: Gene Form
   

kdpF gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

kdpB kdpA ybfA kdpF KdpE anti-anti-terminator anti-anti-terminator anti-terminator terminator terminator terminator TSS_830 TSS_830 ybfAp8 ybfAp8 TSS_828 (cluster) TSS_828 (cluster) ybfAp7 ybfAp7 kdpFp kdpFp

Gene      
Name: kdpF    Texpresso search in the literature
Synonym(s): ECK0687, G0-10439, b4513
Genome position(nucleotides): 728732 <-- 728821 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
48.89
External database links:  
ASAP:
ABE-0285034
ECHOBASE:
EB2047
PortEco:
kdpF
STRING:
511145.b4513
COLOMBOS: kdpF


Product      
Name: K+ transporting P-type ATPase subunit KdpF
Synonym(s): KdpF
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 3.072
Isoelectric point: 3.846
Motif(s):
 
Type Positions Sequence
7 -> 29 TGVLLVFLLLGYLVYALINAEAF
3 -> 24 AGVITGVLLVFLLLGYLVYALI

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.3 - The P-type ATPase (P-ATPase) Superfamily
Gene Ontology Terms (GO)  
cellular_component GO:0031004 - potassium ion-transporting ATPase complex
GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0008556 - potassium transmembrane transporter activity, phosphorylative mechanism
biological_process GO:0006811 - ion transport
GO:0006813 - potassium ion transport
GO:0043462 - regulation of ATPase activity
GO:0071805 - potassium ion transmembrane transport
GO:0098655 - cation transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Altendorf K., et al., 1998
[2] Gassel M., et al., 1999
External database links:  
ECOCYC:
MONOMER0-12
ECOLIWIKI:
b4513
INTERPRO:
IPR011726
PDB:
6HRA
PDB:
5MRW
PDB:
6HRB
PFAM:
PF09604
REFSEQ:
YP_588443
SMR:
P36937
UNIPROT:
P36937


Operon      
Name: kdpFABC         
Operon arrangement:
Transcription unit        Promoter
kdpFABC


Transcriptional Regulation      
Display Regulation             
Activated by: KdpE


RNA cis-regulatory element    
Attenuation: Translational


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter ybfAp7 729037 forward Similarity to the consensus
Read more >
[ICWHO] [3]
  promoter TSS_828 (cluster) 729071 forward For this promoter, there
Read more >
[RS-EPT-CBR] [4]
  promoter ybfAp8 729082 forward Similarity to the consensus
Read more >
[ICWHO], [RS-EPT-CBR] [3], [4]
  promoter TSS_830 729088 forward nd [RS-EPT-CBR] [4]


Evidence    

 [ICWHO] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Altendorf K., Gassel M., Puppe W., Mollenkamp T., Zeeck A., Boddien C., Fendler K., Bamberg E., Drose S., 1998, Structure and function of the Kdp-ATPase of Escherichia coli., Acta Physiol Scand Suppl 643:137-46

 [2] Gassel M., Mollenkamp T., Puppe W., Altendorf K., 1999, The KdpF subunit is part of the K(+)-translocating Kdp complex of Escherichia coli and is responsible for stabilization of the complex in vitro., J Biol Chem 274(53):37901-7

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [4] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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