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ZraR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
phosphate ZraP ZraR ZraS zraP zraP_mRNA zraSR zraSR_mRNA ZraR phosphate


Gensor Unit       
Name: ZraR
Signal name: high concentrations of zinc or lead.
Classification:
Groups: GUs related to the two-component system
Gene Ontology Terms (GO): biological_process GO:0071284 - cellular response to lead ion
GO:0071294 - cellular response to zinc ion
GO:0018106 - peptidyl-histidine phosphorylation
GO:0000160 - phosphorelay signal transduction system
GO:0046777 - protein autophosphorylation
GO:0023014 - signal transduction by protein phosphorylation
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cellular_component GO:0005887 - integral component of plasma membrane
GO:0005622 - intracellular
GO:0016020 - membrane
GO:0030288 - outer membrane-bounded periplasmic space
GO:0005886 - plasma membrane
molecular_function GO:0003677 - DNA binding
GO:0050897 - cobalt ion binding
GO:0005507 - copper ion binding
GO:0016151 - nickel cation binding
GO:0000156 - phosphorelay response regulator activity
GO:0000155 - phosphorelay sensor kinase activity
GO:0008270 - zinc ion binding
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Components: Show/Hide Components Table (10 more...)
Function Name Type
protein HydH protein
protein ZraP protein
protein ZraR protein
complex ZraR-phosphate complex
protein ZraS protein
simple_molecule phosphate simple_molecule
gene zraP gene
RNA zraP_mRNA RNA
gene zraSR gene
RNA zraSR_mRNA RNA


Reactions       
Showing 7 reactions
phosphate + ZraR ZraR-phosphate
Name: phosphate + ZraR -> ZraR-phosphate
Description: Reaction transforming phosphate, ZraR into ZraR-phosphate
Type: state transition
Pathway Components: phosphate + ZraR -> ZraR-phosphate
Components:
Function Name Type Evidence Reference(s)
reactant ZraR protein nd nd
product ZraR-phosphate complex nd nd
reactant phosphate simple_molecule nd nd
ZraR-phosphate zraP zraP_mRNA
Name: zraP -> zraP_mRNA
Description: Transcription of transcription unit zraP. Reaction activation by ZraR-phosphate.
Type: transcription
Pathway Components: zraP - ZraR-phosphate -> zraP_mRNA
Components:
Function Name Type Evidence Reference(s)
activator ZraR-phosphate complex nd nd
reactant zraP gene nd nd
product zraP_mRNA RNA nd nd
ZraR-phosphate zraSR zraSR_mRNA
Name: zraSR -> zraSR_mRNA
Description: Transcription of transcription unit zraSR. Reaction activation by ZraR-phosphate.
Type: transcription
Pathway Components: zraSR - ZraR-phosphate -> zraSR_mRNA
Components:
Function Name Type Evidence Reference(s)
activator ZraR-phosphate complex nd nd
reactant zraSR gene nd nd
product zraSR_mRNA RNA nd nd
zraSR_mRNA ZraS
Name: zraSR_mRNA -> ZraS
Description: Translation of ZraS
Type: translation
Pathway Components: zraSR_mRNA -> ZraS
Components:
Function Name Type Evidence Reference(s)
product ZraS protein nd nd
reactant zraSR_mRNA RNA nd nd
zraSR_mRNA HydH
Name: zraSR_mRNA -> HydH
Description: Translation of HydH
Type: translation
Pathway Components: zraSR_mRNA -> HydH
Components:
Function Name Type Evidence Reference(s)
product HydH protein nd nd
reactant zraSR_mRNA RNA nd nd
zraSR_mRNA ZraR
Name: zraSR_mRNA -> ZraR
Description: Translation of ZraR
Type: translation
Pathway Components: zraSR_mRNA -> ZraR
Components:
Function Name Type Evidence Reference(s)
product ZraR protein nd nd
reactant zraSR_mRNA RNA nd nd
zraP_mRNA ZraP
Name: zraP_mRNA -> ZraP
Description: Translation of ZraP
Type: translation
Pathway Components: zraP_mRNA -> ZraP
Components:
Function Name Type Evidence Reference(s)
product ZraP protein nd nd
reactant zraP_mRNA RNA nd nd



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