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YqhC Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
1,2-propanediol 4NBZ glycoaldehyde oxopropanal glycol RCHO acetol 3-hydroxypropanal lactaldehyde 4NBA yqhD-dkgA 1,3-propanediol yqhD-dkgA_mRNA isobutanol ethyl-2-methylacetoacetate sorbosonate 1,3,4-butanetriol DkgA 2,5-diketo-D-gluconate ethyl-(2R)-methyl-(3S)-hydroxybutanoate 3,4-dihydroxybutanal YqhC alcohol isobutanal YqhD


Gensor Unit       
Name: YqhC
Classification:
Groups: Secondary metabolites biosynthesis, transport and catabolism
Energy production and conversion
Gene Ontology Terms (GO): biological_process GO:0019853 - L-ascorbic acid biosynthetic process
GO:0051596 - methylglyoxal catabolic process
GO:0000302 - response to reactive oxygen species
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0050580 - 2,5-didehydrogluconate reductase activity
GO:0008106 - alcohol dehydrogenase (NADP+) activity
GO:0018455 - alcohol dehydrogenase [NAD(P)+] activity
GO:0046872 - metal ion binding
GO:1990002 - methylglyoxal reductase (NADPH-dependent, acetol producing)
GO:0016491 - oxidoreductase activity
GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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Components:
  Function Name Type
  simple_molecule 1,2-propanediol simple_molecule
  simple_molecule 1,3,4-butanetriol simple_molecule
  simple_molecule 1,3-propanediol simple_molecule
  simple_molecule 2,5-diketo-D-gluconate simple_molecule
  simple_molecule 3,4-dihydroxybutanal simple_molecule
  simple_molecule 3-hydroxypropanal simple_molecule
  simple_molecule 4NBA simple_molecule
  simple_molecule 4NBZ simple_molecule
  protein DkgA protein
  simple_molecule RCHO simple_molecule
  protein YqhC protein
  protein YqhD protein
  simple_molecule acetol simple_molecule
  simple_molecule alcohol simple_molecule
  simple_molecule ethyl-(2R)-methyl-(3S)-hydroxybutanoate simple_molecule
  simple_molecule ethyl-2-methylacetoacetate simple_molecule
  simple_molecule glycoaldehyde simple_molecule
  simple_molecule glycol simple_molecule
  simple_molecule isobutanal simple_molecule
  simple_molecule isobutanol simple_molecule
  simple_molecule lactaldehyde simple_molecule
  simple_molecule oxopropanal simple_molecule
  simple_molecule sorbosonate simple_molecule
  gene yqhD-dkgA gene
  RNA yqhD-dkgA_mRNA RNA


Reactions       
Showing 13 reactions
YqhC yqhD-dkgA yqhD-dkgA_mRNA
Name: yqhD-dkgA -> yqhD-dkgA_mRNA
Description: Transcription of transcription unit yqhD-dkgA. Reaction activation by YqhC.
Type: transcription
Pathway Components: yqhD-dkgA - YqhC -> yqhD-dkgA_mRNA
Components:
Function Name Type
activator YqhC protein
reactant yqhD-dkgA gene
product yqhD-dkgA_mRNA RNA
yqhD-dkgA_mRNA YqhD
Name: yqhD-dkgA_mRNA -> YqhD
Description: Translation of YqhD
Type: translation
Pathway Components: yqhD-dkgA_mRNA -> YqhD
Components:
Function Name Type
product YqhD protein
reactant yqhD-dkgA_mRNA RNA
YqhD glycoaldehyde glycol
Name: glycoaldehyde -> glycol
Description: Reaction transforming glycoaldehyde into glycol
Type: state transition
Pathway Components: glycoaldehyde - YqhD -> glycol
Components:
Function Name Type
catalyzer YqhD protein
reactant glycoaldehyde simple_molecule
product glycol simple_molecule
DkgA YqhD oxopropanal acetol
Name: oxopropanal -> acetol
Description: Reaction transforming oxopropanal into acetol
Type: state transition
Pathway Components: oxopropanal - DkgA - YqhD -> acetol
Components:
Function Name Type
catalyzer DkgA protein
catalyzer YqhD protein
product acetol simple_molecule
reactant oxopropanal simple_molecule
YqhD RCHO alcohol
Name: RCHO -> alcohol
Description: Reaction transforming RCHO into alcohol
Type: state transition
Pathway Components: RCHO - YqhD -> alcohol
Components:
Function Name Type
reactant RCHO simple_molecule
catalyzer YqhD protein
product alcohol simple_molecule
YqhD lactaldehyde 1,2-propanediol
Name: lactaldehyde -> 1,2-propanediol
Description: Reaction transforming lactaldehyde into 1,2-propanediol
Type: state transition
Pathway Components: lactaldehyde - YqhD -> 1,2-propanediol
Components:
Function Name Type
product 1,2-propanediol simple_molecule
catalyzer YqhD protein
reactant lactaldehyde simple_molecule
YqhD 4NBZ 4NBA
Name: 4NBZ -> 4NBA
Description: Reaction transforming 4NBZ into 4NBA
Type: state transition
Pathway Components: 4NBZ - YqhD -> 4NBA
Components:
Function Name Type
product 4NBA simple_molecule
reactant 4NBZ simple_molecule
catalyzer YqhD protein
YqhD 1,3-propanediol 3-hydroxypropanal
Name: 1,3-propanediol -> 3-hydroxypropanal
Description: Reaction transforming 1,3-propanediol into 3-hydroxypropanal
Type: state transition
Pathway Components: 1,3-propanediol - YqhD -> 3-hydroxypropanal
Components:
Function Name Type
reactant 1,3-propanediol simple_molecule
product 3-hydroxypropanal simple_molecule
catalyzer YqhD protein
YqhD 3,4-dihydroxybutanal 1,3,4-butanetriol
Name: 3,4-dihydroxybutanal -> 1,3,4-butanetriol
Description: Reaction transforming 3,4-dihydroxybutanal into 1,3,4-butanetriol
Type: state transition
Pathway Components: 3,4-dihydroxybutanal - YqhD -> 1,3,4-butanetriol
Components:
Function Name Type
product 1,3,4-butanetriol simple_molecule
reactant 3,4-dihydroxybutanal simple_molecule
catalyzer YqhD protein
yqhD-dkgA_mRNA DkgA
Name: yqhD-dkgA_mRNA -> DkgA
Description: Translation of DkgA
Type: translation
Pathway Components: yqhD-dkgA_mRNA -> DkgA
Components:
Function Name Type
product DkgA protein
reactant yqhD-dkgA_mRNA RNA
DkgA isobutanal isobutanol
Name: isobutanal -> isobutanol
Description: Reaction transforming isobutanal into isobutanol
Type: state transition
Pathway Components: isobutanal - DkgA -> isobutanol
Components:
Function Name Type
catalyzer DkgA protein
reactant isobutanal simple_molecule
product isobutanol simple_molecule
DkgA ethyl-2-methylacetoacetate ethyl-(2R)-methyl-(3S)-hydroxybutanoate
Name: ethyl-2-methylacetoacetate -> ethyl-(2R)-methyl-(3S)-hydroxybutanoate
Description: Reaction transforming ethyl-2-methylacetoacetate into ethyl-(2R)-methyl-(3S)-hydroxybutanoate
Type: state transition
Pathway Components: ethyl-2-methylacetoacetate - DkgA -> ethyl-(2R)-methyl-(3S)-hydroxybutanoate
Components:
Function Name Type
catalyzer DkgA protein
product ethyl-(2R)-methyl-(3S)-hydroxybutanoate simple_molecule
reactant ethyl-2-methylacetoacetate simple_molecule
DkgA 2,5-diketo-D-gluconate sorbosonate
Name: 2,5-diketo-D-gluconate -> sorbosonate
Description: Reaction transforming 2,5-diketo-D-gluconate into sorbosonate
Type: state transition
Pathway Components: 2,5-diketo-D-gluconate - DkgA -> sorbosonate
Components:
Function Name Type
reactant 2,5-diketo-D-gluconate simple_molecule
catalyzer DkgA protein
product sorbosonate simple_molecule



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