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XylR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
1-deoxy-D-xylulose 1-deoxy-D-xylulose 5-phosphate D-xylulose D-xylulose-5-P XylA XylB XylF XylG XylH XylR D-xylose D-xylose_Ext phosphate xylAB xylAB_mRNA xylFGHR xylFGHR_mRNA XylR D-xylose XylG XylH XylF


Gensor Unit       
Name: XylR
Description: Molecular biology level
Detailed: In the presence of xylose, XylR positively regulates its own expression and the expression of genes required for Xylose transport and catabolism. Under these conditions, XylR is modified to XylR-xylose, binds its target sites enabling the expression of its regulated genes.
Less detailed: In the presence of xylose, XylR positively regulates the expression of genes needed for xylose transport and catabolic process.

Physiology level
Detailed: The presence of xylose induces the expression of genes involved with xylose transport and catabolic process. Under these conditions the genes necessary for transport of xylose and its conversion to xylulose-5-phosphate, an intermediate of the pentose phosphate pathway; are expressed.
Less detailed: The presence of xylose induces the expression of genes needful for xylose transport and its conversion to xylulose-5-phosphate, an intermediate of the pentose phosphate pathway.
Classification:
Groups: GUs related to carbon source utilization
Gene Ontology Terms (GO): biological_process GO:0015752 - D-ribose transmembrane transport
GO:0042843 - D-xylose catabolic process
GO:0042732 - D-xylose metabolic process
GO:0015753 - D-xylose transmembrane transport
GO:0046835 - carbohydrate phosphorylation
GO:0015749 - monosaccharide transmembrane transport
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cellular_component GO:0043190 - ATP-binding cassette (ABC) transporter complex
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0030288 - outer membrane-bounded periplasmic space
GO:0005886 - plasma membrane
molecular_function GO:0005524 - ATP binding
GO:0015148 - D-xylose transmembrane transporter activity
GO:0003700 - DNA binding transcription factor activity
GO:0030246 - carbohydrate binding
GO:0048029 - monosaccharide binding
GO:0015145 - monosaccharide transmembrane transporter activity
GO:0009045 - xylose isomerase activity
Read more >
Components: Show/Hide Components Table (19 more...)
Function Name Type
simple_molecule 1-deoxy-xylulose simple_molecule
simple_molecule DOXP simple_molecule
protein XylA protein
protein XylB protein
protein XylF protein
protein XylG protein
complex XylG-XylH-XylF complex
protein XylH protein
protein XylR protein
complex XylR-xylose complex
gene xylAB gene
RNA xylAB_mRNA RNA
gene xylFGHR gene
RNA xylFGHR_mRNA RNA
simple_molecule xylopyranose simple_molecule
simple_molecule xylose simple_molecule
simple_molecule xylose_Ext simple_molecule
simple_molecule xylulose simple_molecule
simple_molecule xylulose-P simple_molecule


Reactions       
Showing 14 reactions
xylose + XylR XylR-xylose
Name: xylose + XylR -> XylR-xylose
Description: Reaction transforming xylose, XylR into XylR-xylose
Type: state transition
Pathway Components: xylose + XylR -> XylR-xylose
Components:
Function Name Type Evidence Reference(s)
reactant XylR protein nd nd
product XylR-xylose complex nd nd
reactant xylose simple_molecule nd nd
XylR-xylose xylAB xylAB_mRNA
Name: xylAB -> xylAB_mRNA
Description: Transcription of transcription unit xylAB. Reaction activation by XylR-xylose.
Type: transcription
Pathway Components: xylAB - XylR-xylose -> xylAB_mRNA
Components:
Function Name Type Evidence Reference(s)
activator XylR-xylose complex nd nd
reactant xylAB gene nd nd
product xylAB_mRNA RNA nd nd
XylR-xylose xylFGHR xylFGHR_mRNA
Name: xylFGHR -> xylFGHR_mRNA
Description: Transcription of transcription unit xylFGHR. Reaction activation by XylR-xylose.
Type: transcription
Pathway Components: xylFGHR - XylR-xylose -> xylFGHR_mRNA
Components:
Function Name Type Evidence Reference(s)
activator XylR-xylose complex nd nd
reactant xylFGHR gene nd nd
product xylFGHR_mRNA RNA nd nd
xylAB_mRNA XylA
Name: xylAB_mRNA -> XylA
Description: Translation of XylA
Type: translation
Pathway Components: xylAB_mRNA -> XylA
Components:
Function Name Type Evidence Reference(s)
product XylA protein nd nd
reactant xylAB_mRNA RNA nd nd
XylA xylopyranose xylulose
Name: xylopyranose -> xylulose
Description: Reaction transforming xylopyranose into xylulose
Type: state transition
Pathway Components: xylopyranose - XylA -> xylulose
Components:
Function Name Type Evidence Reference(s)
catalyzer XylA protein nd nd
reactant xylopyranose simple_molecule nd nd
product xylulose simple_molecule nd nd
xylAB_mRNA XylB
Name: xylAB_mRNA -> XylB
Description: Translation of XylB
Type: translation
Pathway Components: xylAB_mRNA -> XylB
Components:
Function Name Type Evidence Reference(s)
product XylB protein nd nd
reactant xylAB_mRNA RNA nd nd
XylB xylulose xylulose-P
Name: xylulose -> xylulose-P
Description: Reaction transforming xylulose into xylulose-P
Type: state transition
Pathway Components: xylulose - XylB -> xylulose-P
Components:
Function Name Type Evidence Reference(s)
catalyzer XylB protein nd nd
reactant xylulose simple_molecule nd nd
product xylulose-P simple_molecule nd nd
XylB 1-deoxy-xylulose DOXP
Name: 1-deoxy-xylulose -> DOXP
Description: Reaction transforming 1-deoxy-xylulose into DOXP
Type: state transition
Pathway Components: 1-deoxy-xylulose - XylB -> DOXP
Components:
Function Name Type Evidence Reference(s)
reactant 1-deoxy-xylulose simple_molecule nd nd
product DOXP simple_molecule nd nd
catalyzer XylB protein nd nd
xylFGHR_mRNA XylF
Name: xylFGHR_mRNA -> XylF
Description: Translation of XylF
Type: translation
Pathway Components: xylFGHR_mRNA -> XylF
Components:
Function Name Type Evidence Reference(s)
product XylF protein nd nd
reactant xylFGHR_mRNA RNA nd nd
XylF + XylG + XylH XylG-XylH-XylF
Name: XylF + XylG + XylH -> XylG-XylH-XylF
Description: Reaction transforming XylF, XylG, XylH into XylG-XylH-XylF
Type: state transition
Pathway Components: XylF + XylG + XylH -> XylG-XylH-XylF
Components:
Function Name Type Evidence Reference(s)
reactant XylF protein nd nd
reactant XylG protein nd nd
product XylG-XylH-XylF complex nd nd
reactant XylH protein nd nd
XylG-XylH-XylF xylose_Ext xylose
Name: xylose_Ext -> xylose
Description: Transport of xylose_Ext through a bacterial membrane, leading to the presence of xylose inside the cell.
Type: transport
Pathway Components: xylose_Ext - XylG-XylH-XylF -> xylose
Components:
Function Name Type Evidence Reference(s)
catalyzer XylG-XylH-XylF complex nd nd
product xylose simple_molecule nd nd
reactant xylose_Ext simple_molecule nd nd
xylFGHR_mRNA XylG
Name: xylFGHR_mRNA -> XylG
Description: Translation of XylG
Type: translation
Pathway Components: xylFGHR_mRNA -> XylG
Components:
Function Name Type Evidence Reference(s)
product XylG protein nd nd
reactant xylFGHR_mRNA RNA nd nd
xylFGHR_mRNA XylH
Name: xylFGHR_mRNA -> XylH
Description: Translation of XylH
Type: translation
Pathway Components: xylFGHR_mRNA -> XylH
Components:
Function Name Type Evidence Reference(s)
product XylH protein nd nd
reactant xylFGHR_mRNA RNA nd nd
xylFGHR_mRNA XylR
Name: xylFGHR_mRNA -> XylR
Description: Translation of XylR
Type: translation
Pathway Components: xylFGHR_mRNA -> XylR
Components:
Function Name Type Evidence Reference(s)
product XylR protein nd nd
reactant xylFGHR_mRNA RNA nd nd



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