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UhpA Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
D-fructose 6-phosphate D-fructose 6-phosphate_Ext L-GAP L-GAP_Ext UhpA UhpT alpha-D-mannose-6-phosphate alpha-D-mannose-6-phosphate_Ext beta-D-glucose-6-P beta-D-glucose-6-P_Ext uhpT uhpT_mRNA UhpA phosphate phosphate phosphate phosphate_Ext phosphate_Ext


Gensor Unit       
Name: UhpA
Signal name: glucose 6-phosphate.
Classification:
Groups: GUs related to the two-component system
Gene Ontology Terms (GO): biological_process GO:0015760 - glucose-6-phosphate transport
GO:0015712 - hexose phosphate transport
GO:0035435 - phosphate ion transmembrane transport
GO:0006817 - phosphate ion transport
GO:0055085 - transmembrane transport
cellular_component GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0005886 - plasma membrane
molecular_function GO:0015526 - hexose-phosphate:inorganic phosphate antiporter activity
Components: Show/Hide Components Table (14 more...)
Function Name Type
simple_molecule α-D-mannose-6-P simple_molecule
simple_molecule α-D-mannose-6-P_Ext simple_molecule
simple_molecule GAP simple_molecule
simple_molecule GAP_Ext simple_molecule
protein UhpA protein
complex UhpA-phosphate complex
protein UhpT protein
simple_molecule beta-D-glucose-6-P simple_molecule
simple_molecule beta-D-glucose-6-P_Ext simple_molecule
simple_molecule fructose-6-P simple_molecule
simple_molecule fructose-6-P_Ext simple_molecule
simple_molecule phosphate simple_molecule
gene uhpT gene
RNA uhpT_mRNA RNA


Reactions       
Showing 7 reactions
phosphate + UhpA UhpA-phosphate
Name: phosphate + UhpA -> UhpA-phosphate
Description: Reaction transforming phosphate, UhpA into UhpA-phosphate
Type: state transition
Pathway Components: phosphate + UhpA -> UhpA-phosphate
Components:
Function Name Type Evidence Reference(s)
reactant UhpA protein nd nd
product UhpA-phosphate complex nd nd
reactant phosphate simple_molecule nd nd
UhpA-phosphate uhpT uhpT_mRNA
Name: uhpT -> uhpT_mRNA
Description: Transcription of transcription unit uhpT. Reaction activation by UhpA-phosphate.
Type: transcription
Pathway Components: uhpT - UhpA-phosphate -> uhpT_mRNA
Components:
Function Name Type Evidence Reference(s)
activator UhpA-phosphate complex nd nd
reactant uhpT gene nd nd
product uhpT_mRNA RNA nd nd
uhpT_mRNA UhpT
Name: uhpT_mRNA -> UhpT
Description: Translation of UhpT
Type: translation
Pathway Components: uhpT_mRNA -> UhpT
Components:
Function Name Type Evidence Reference(s)
product UhpT protein nd nd
reactant uhpT_mRNA RNA nd nd
UhpT GAP_Ext GAP
Name: GAP_Ext -> GAP
Description: Transport of GAP_Ext through a bacterial membrane, leading to the presence of GAP inside the cell.
Type: transport
Pathway Components: GAP_Ext - UhpT -> GAP
Components:
Function Name Type Evidence Reference(s)
product GAP simple_molecule nd nd
reactant GAP_Ext simple_molecule nd nd
catalyzer UhpT protein nd nd
UhpT α-D-mannose-6-P_Ext α-D-mannose-6-P
Name: α-D-mannose-6-P_Ext -> α-D-mannose-6-P
Description: Transport of α-D-mannose-6-P_Ext through a bacterial membrane, leading to the presence of α-D-mannose-6-P inside the cell.
Type: transport
Pathway Components: α-D-mannose-6-P_Ext - UhpT -> α-D-mannose-6-P
Components:
Function Name Type Evidence Reference(s)
product α-D-mannose-6-P simple_molecule nd nd
reactant α-D-mannose-6-P_Ext simple_molecule nd nd
catalyzer UhpT protein nd nd
UhpT fructose-6-P_Ext fructose-6-P
Name: fructose-6-P_Ext -> fructose-6-P
Description: Transport of fructose-6-P_Ext through a bacterial membrane, leading to the presence of fructose-6-P inside the cell.
Type: transport
Pathway Components: fructose-6-P_Ext - UhpT -> fructose-6-P
Components:
Function Name Type Evidence Reference(s)
catalyzer UhpT protein nd nd
product fructose-6-P simple_molecule nd nd
reactant fructose-6-P_Ext simple_molecule nd nd
UhpT beta-D-glucose-6-P_Ext beta-D-glucose-6-P
Name: beta-D-glucose-6-P_Ext -> beta-D-glucose-6-P
Description: Transport of beta-D-glucose-6-P_Ext through a bacterial membrane, leading to the presence of beta-D-glucose-6-P inside the cell.
Type: transport
Pathway Components: beta-D-glucose-6-P_Ext - UhpT -> beta-D-glucose-6-P
Components:
Function Name Type Evidence Reference(s)
catalyzer UhpT protein nd nd
product beta-D-glucose-6-P simple_molecule nd nd
reactant beta-D-glucose-6-P_Ext simple_molecule nd nd



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