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TrpR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
indole-3-glycerol-P 1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate DAHP PRPP AroH AroL AroM CO2 erythrose-4P D-glyceraldehyde 3-phosphate L-glutamate L-glutamine L-serine L-tryptophan L-tryptophan_Ext Mtr 5-P-ribosyl-anthranilate TrpA TrpB TrpC TrpD TrpE TrpL TrpR L-tryptophan YaiA vitamin L1 aroH aroH_mRNA aroL-yaiA-aroM aroL-yaiA-aroM_mRNA chorismate PP indole indole_Ext mtr mtr_mRNA phosphate PEP pyruvate shikimate shikimate-5-P trpL trpLEDCBA trpLEDCBA_mRNA trpL_mRNA trpR trpR_mRNA TrpR L-tryptophan TrpE TrpD


Gensor Unit       
Name: TrpR
Classification:
Groups: GUs related to the metabolism of amino acids
Gene Ontology Terms (GO): GO:0016833 - oxo-acid-lyase activity
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0045892 - negative regulation of transcription, DNA-templated
GO:0016020 - membrane
GO:0008652 - cellular amino acid biosynthetic process
GO:0005622 - intracellular
GO:0003824 - catalytic activity
GO:0090357 - regulation of tryptophan metabolic process
GO:0005887 - integral component of plasma membrane
GO:0022804 - active transmembrane transporter activity
GO:0004834 - tryptophan synthase activity
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Components:
Function Name Type
simple molecule tryptophan simple molecule


Reactions       
Showing 20 reactions
tryptophan + TrpR TrpR-tryptophan
Name: tryptophan + TrpR -> TrpR-tryptophan
Description: Reaction transforming tryptophan, TrpR into TrpR-tryptophan
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product TrpR-tryptophan complex nd nd
reactant tryptophan simple molecule nd nd
reactant TrpR protein nd nd
aroH aroH_mRNA
Name: aroH -> aroH_mRNA
Description: Transcription of transcription unit aroH; reaction inhibition by TrpR-tryptophan.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product aroH_mRNA RNA nd nd
reactant aroH transcription unit nd nd
aroL-yaiA-aroM aroL-yaiA-aroM_mRNA
Name: aroL-yaiA-aroM -> aroL-yaiA-aroM_mRNA
Description: Transcription of transcription unit aroL-yaiA-aroM; reaction inhibition by TrpR-tryptophan.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant aroL-yaiA-aroM transcription unit nd nd
product aroL-yaiA-aroM_mRNA RNA nd nd
mtr mtr_mRNA
Name: mtr -> mtr_mRNA
Description: Transcription of transcription unit mtr; reaction inhibition by HU.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant mtr gene nd nd
product mtr_mRNA RNA nd nd
trpLEDCBA trpLEDCBA_mRNA
Name: trpLEDCBA -> trpLEDCBA_mRNA
Description: Transcription of transcription unit trpLEDCBA; reaction inhibition by TrpR-tryptophan.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product trpLEDCBA_mRNA RNA nd nd
reactant trpLEDCBA transcription unit nd nd
trpR trpR_mRNA
Name: trpR -> trpR_mRNA
Description: Transcription of transcription unit trpR; reaction inhibition by TrpR-tryptophan.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant trpR transcription unit nd nd
product trpR_mRNA RNA nd nd
trpL trpL_mRNA
Name: trpL -> trpL_mRNA
Description: Transcription of transcription unit trpL; reaction inhibition by TrpR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant trpL transcription unit nd nd
product trpL_mRNA RNA nd nd
mtr_mRNA Mtr
Name: mtr_mRNA -> Mtr
Description: Translation of Mtr
Type: translation
Components:
Function Name Type Evidence Reference(s)
product Mtr protein nd nd
reactant mtr_mRNA RNA nd nd
trpL_mRNA TrpL
Name: trpL_mRNA -> TrpL
Description: Translation of TrpL
Type: translation
Components:
Function Name Type Evidence Reference(s)
product trpL_mRNA RNA nd nd
reactant trpL_mRNA RNA nd nd
aroL-yaiA-aroM_mRNA AroL
Name: aroL-yaiA-aroM_mRNA -> AroL
Description: Translation of AroL
Type: translation
Components:
Function Name Type Evidence Reference(s)
product aroL-yaiA-aroM_mRNA RNA nd nd
reactant aroL-yaiA-aroM_mRNA RNA nd nd
aroL-yaiA-aroM_mRNA YaiA
Name: aroL-yaiA-aroM_mRNA -> YaiA
Description: Translation of YaiA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product aroL-yaiA-aroM_mRNA RNA nd nd
reactant aroL-yaiA-aroM_mRNA RNA nd nd
aroL-yaiA-aroM_mRNA AroM
Name: aroL-yaiA-aroM_mRNA -> AroM
Description: Translation of AroM
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant aroL-yaiA-aroM_mRNA RNA nd nd
product aroL-yaiA-aroM_mRNA RNA nd nd
trpLEDCBA_mRNA TrpL
Name: trpLEDCBA_mRNA -> TrpL
Description: Translation of TrpL
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant trpLEDCBA_mRNA RNA nd nd
product trpLEDCBA_mRNA RNA nd nd
trpLEDCBA_mRNA TrpE
Name: trpLEDCBA_mRNA -> TrpE
Description: Translation of TrpE
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant trpLEDCBA_mRNA RNA nd nd
product trpLEDCBA_mRNA RNA nd nd
trpLEDCBA_mRNA TrpD
Name: trpLEDCBA_mRNA -> TrpD
Description: Translation of TrpD
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant trpLEDCBA_mRNA RNA nd nd
product trpLEDCBA_mRNA RNA nd nd
trpLEDCBA_mRNA TrpC
Name: trpLEDCBA_mRNA -> TrpC
Description: Translation of TrpC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product trpLEDCBA_mRNA RNA nd nd
reactant trpLEDCBA_mRNA RNA nd nd
trpLEDCBA_mRNA TrpB
Name: trpLEDCBA_mRNA -> TrpB
Description: Translation of TrpB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant trpLEDCBA_mRNA RNA nd nd
product trpLEDCBA_mRNA RNA nd nd
trpLEDCBA_mRNA TrpA
Name: trpLEDCBA_mRNA -> TrpA
Description: Translation of TrpA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product trpLEDCBA_mRNA RNA nd nd
reactant trpLEDCBA_mRNA RNA nd nd
trpR_mRNA TrpR
Name: trpR_mRNA -> TrpR
Description: Translation of TrpR
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant trpR_mRNA RNA nd nd
product TrpR protein nd nd
aroH_mRNA AroH
Name: aroH_mRNA -> AroH
Description: Translation of AroH
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant aroH_mRNA RNA nd nd
product aroH_mRNA RNA nd nd



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