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TorR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
GABA CO2 GadA GadX HdeA HdeB L-cysteine L-glutamate L-tryptophan L-tryptophan_Ext phosphate TnaA TnaB TnaC TorA TorC TorD TorI TorR YhiD a menaquinol menaquinone ammonia gadAX gadAX_mRNA hdeAB-yhiD hdeAB-yhiD_mRNA sulfide indole pyruvate tnaC tnaCAB tnaCAB_mRNA tnaC_mRNA torCAD torCAD_mRNA torR torR_mRNA (CH3)3NH TMAO TorR phosphate TorR TorI TorC TorA


Gensor Unit       
Name: TorR
Signal name: trimethylamine N-oxide (TMAO).
Classification:
Groups: GUs related to the two-component system
Gene Ontology Terms (GO): biological_process GO:0009060 - aerobic respiration
GO:0003333 - amino acid transmembrane transport
GO:0009061 - anaerobic respiration
GO:0006974 - cellular response to DNA damage stimulus
GO:0071468 - cellular response to acidic pH
GO:0006538 - glutamate catabolic process
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cellular_component GO:0060187 - cell pole
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0016020 - membrane
GO:0030288 - outer membrane-bounded periplasmic space
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molecular_function GO:0003700 - DNA binding transcription factor activity
GO:0080146 - L-cysteine desulfhydrase activity
GO:0001216 - bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GO:0000986 - bacterial-type proximal promoter sequence-specific DNA binding
GO:0051087 - chaperone binding
GO:0048037 - cofactor binding
GO:0009055 - electron transfer activity
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Components: Show/Hide Components Table (45 more...)
Function Name Type
simple_molecule (CH3)3NH simple_molecule
simple_molecule CO2 simple_molecule
simple_molecule GABA simple_molecule
protein GadA protein
protein GadW protein
protein GadX protein
protein HdeA protein
protein HdeB protein
simple_molecule L-glutamate simple_molecule
simple_molecule TMAO simple_molecule
protein TnaA protein
protein TnaB protein
protein TnaC protein
protein TorA protein
protein TorC protein
complex TorC-TorA complex
protein TorD protein
protein TorI protein
protein TorR protein
complex TorR-TorI complex
complex TorR-phosphate complex
protein YhiD protein
simple_molecule cysteine simple_molecule
simple_molecule dehydroalanine simple_molecule
gene gadAX gene
gene gadAXW gene
RNA gadAXW_mRNA RNA
RNA gadAX_mRNA RNA
gene hdeAB-yhiD gene
RNA hdeAB-yhiD_mRNA RNA
simple_molecule indole simple_molecule
simple_molecule menaquinol simple_molecule
simple_molecule phosphate simple_molecule
simple_molecule sulfide simple_molecule
gene tnaC gene
gene tnaCAB gene
RNA tnaCAB_mRNA RNA
RNA tnaC_mRNA RNA
gene torCAD gene
RNA torCAD_mRNA RNA
gene torR gene
RNA torR_mRNA RNA
simple_molecule tryptophan simple_molecule
simple_molecule tryptophan_Ext simple_molecule
simple_molecule vitamin K2 simple_molecule


Reactions       
Showing 31 reactions
phosphate + TorR TorR-phosphate
Name: phosphate + TorR -> TorR-phosphate
Description: Reaction transforming phosphate, TorR into TorR-phosphate
Type: state transition
Pathway Components: phosphate + TorR -> TorR-phosphate
Components:
Function Name Type Evidence Reference(s)
reactant TorR protein nd nd
product TorR-phosphate complex nd nd
reactant phosphate simple_molecule nd nd
TorR-phosphate hdeAB-yhiD hdeAB-yhiD_mRNA
Name: hdeAB-yhiD -> hdeAB-yhiD_mRNA
Description: Transcription of transcription unit hdeAB-yhiD. Reaction activation by TorR-phosphate.
Type: transcription
Pathway Components: hdeAB-yhiD - TorR-phosphate -> hdeAB-yhiD_mRNA
Components:
Function Name Type Evidence Reference(s)
activator TorR-phosphate complex nd nd
reactant hdeAB-yhiD gene nd nd
product hdeAB-yhiD_mRNA RNA nd nd
TorR-phosphate tnaCAB tnaCAB_mRNA
Name: tnaCAB -> tnaCAB_mRNA
Description: Transcription of transcription unit tnaCAB. Reaction activation by TorR-phosphate.
Type: transcription
Pathway Components: tnaCAB - TorR-phosphate -> tnaCAB_mRNA
Components:
Function Name Type Evidence Reference(s)
activator TorR-phosphate complex nd nd
reactant tnaCAB gene nd nd
product tnaCAB_mRNA RNA nd nd
TorR-phosphate torCAD torCAD_mRNA
Name: torCAD -> torCAD_mRNA
Description: Transcription of transcription unit torCAD. Reaction activation by TorR-phosphate.
Type: transcription
Pathway Components: torCAD - TorR-phosphate -> torCAD_mRNA
Components:
Function Name Type Evidence Reference(s)
activator TorR-phosphate complex nd nd
reactant torCAD gene nd nd
product torCAD_mRNA RNA nd nd
TorR-phosphate gadAXW gadAXW_mRNA
Name: gadAXW -> gadAXW_mRNA
Description: Transcription of transcription unit gadAXW. Reaction inhibition by TorR-phosphate.
Type: transcription
Pathway Components: gadAXW - TorR-phosphate -> gadAXW_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor TorR-phosphate complex nd nd
reactant gadAXW gene nd nd
product gadAXW_mRNA RNA nd nd
TorR-phosphate torR torR_mRNA
Name: torR -> torR_mRNA
Description: Transcription of transcription unit torR. Reaction inhibition by TorR-phosphate.
Type: transcription
Pathway Components: torR - TorR-phosphate -> torR_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor TorR-phosphate complex nd nd
reactant torR gene nd nd
product torR_mRNA RNA nd nd
TorI + TorR TorR-TorI
Name: TorI + TorR -> TorR-TorI
Description: Reaction transforming TorI, TorR into TorR-TorI
Type: state transition
Pathway Components: TorI + TorR -> TorR-TorI
Components:
Function Name Type Evidence Reference(s)
reactant TorI protein nd nd
reactant TorR protein nd nd
product TorR-TorI complex nd nd
TorR gadAX gadAX_mRNA
Name: gadAX -> gadAX_mRNA
Description: Transcription of transcription unit gadAX. Reaction inhibition by TorR.
Type: transcription
Pathway Components: gadAX - TorR -> gadAX_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor TorR protein nd nd
reactant gadAX gene nd nd
product gadAX_mRNA RNA nd nd
TorR tnaC tnaC_mRNA
Name: tnaC -> tnaC_mRNA
Description: Transcription of transcription unit tnaC. Reaction activation by TorR.
Type: transcription
Pathway Components: tnaC - TorR -> tnaC_mRNA
Components:
Function Name Type Evidence Reference(s)
activator TorR protein nd nd
reactant tnaC gene nd nd
product tnaC_mRNA RNA nd nd
hdeAB-yhiD_mRNA HdeA
Name: hdeAB-yhiD_mRNA -> HdeA
Description: Translation of HdeA
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> HdeA
Components:
Function Name Type Evidence Reference(s)
product HdeA protein nd nd
reactant hdeAB-yhiD_mRNA RNA nd nd
hdeAB-yhiD_mRNA HdeB
Name: hdeAB-yhiD_mRNA -> HdeB
Description: Translation of HdeB
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> HdeB
Components:
Function Name Type Evidence Reference(s)
product HdeB protein nd nd
reactant hdeAB-yhiD_mRNA RNA nd nd
hdeAB-yhiD_mRNA YhiD
Name: hdeAB-yhiD_mRNA -> YhiD
Description: Translation of YhiD
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> YhiD
Components:
Function Name Type Evidence Reference(s)
product YhiD protein nd nd
reactant hdeAB-yhiD_mRNA RNA nd nd
gadAXW_mRNA GadX
Name: gadAXW_mRNA -> GadX
Description: Translation of GadX
Type: translation
Pathway Components: gadAXW_mRNA -> GadX
Components:
Function Name Type Evidence Reference(s)
product GadX protein nd nd
reactant gadAXW_mRNA RNA nd nd
gadAXW_mRNA GadW
Name: gadAXW_mRNA -> GadW
Description: Translation of GadW
Type: translation
Pathway Components: gadAXW_mRNA -> GadW
Components:
Function Name Type Evidence Reference(s)
product GadW protein nd nd
reactant gadAXW_mRNA RNA nd nd
gadAXW_mRNA GadA
Name: gadAXW_mRNA -> GadA
Description: Translation of GadA
Type: translation
Pathway Components: gadAXW_mRNA -> GadA
Components:
Function Name Type Evidence Reference(s)
product GadA protein nd nd
reactant gadAXW_mRNA RNA nd nd
GadA L-glutamate GABA + CO2
Name: L-glutamate -> GABA + CO2
Description: Reaction transforming L-glutamate into GABA, CO2
Type: state transition
Pathway Components: L-glutamate - GadA -> GABA + CO2
Components:
Function Name Type Evidence Reference(s)
product CO2 simple_molecule nd nd
product GABA simple_molecule nd nd
catalyzer GadA protein nd nd
reactant L-glutamate simple_molecule nd nd
torR_mRNA TorR
Name: torR_mRNA -> TorR
Description: Translation of TorR
Type: translation
Pathway Components: torR_mRNA -> TorR
Components:
Function Name Type Evidence Reference(s)
product TorR protein nd nd
reactant torR_mRNA RNA nd nd
torCAD_mRNA TorC
Name: torCAD_mRNA -> TorC
Description: Translation of TorC
Type: translation
Pathway Components: torCAD_mRNA -> TorC
Components:
Function Name Type Evidence Reference(s)
product TorC protein nd nd
reactant torCAD_mRNA RNA nd nd
TorA + TorC TorC-TorA
Name: TorA + TorC -> TorC-TorA
Description: Reaction transforming TorA, TorC into TorC-TorA
Type: state transition
Pathway Components: TorA + TorC -> TorC-TorA
Components:
Function Name Type Evidence Reference(s)
reactant TorA protein nd nd
reactant TorC protein nd nd
product TorC-TorA complex nd nd
TorC-TorA menaquinol + TMAO vitamin K2 + (CH3)3NH
Name: menaquinol + TMAO -> vitamin K2 + (CH3)3NH
Description: Reaction transforming menaquinol, TMAO into vitamin K2, (CH3)3NH
Type: state transition
Pathway Components: menaquinol + TMAO - TorC-TorA -> vitamin K2 + (CH3)3NH
Components:
Function Name Type Evidence Reference(s)
product (CH3)3NH simple_molecule nd nd
reactant TMAO simple_molecule nd nd
catalyzer TorC-TorA complex nd nd
reactant menaquinol simple_molecule nd nd
product vitamin K2 simple_molecule nd nd
torCAD_mRNA TorA
Name: torCAD_mRNA -> TorA
Description: Translation of TorA
Type: translation
Pathway Components: torCAD_mRNA -> TorA
Components:
Function Name Type Evidence Reference(s)
product TorA protein nd nd
reactant torCAD_mRNA RNA nd nd
torCAD_mRNA TorD
Name: torCAD_mRNA -> TorD
Description: Translation of TorD
Type: translation
Pathway Components: torCAD_mRNA -> TorD
Components:
Function Name Type Evidence Reference(s)
product TorD protein nd nd
reactant torCAD_mRNA RNA nd nd
tnaCAB_mRNA TnaC
Name: tnaCAB_mRNA -> TnaC
Description: Translation of TnaC
Type: translation
Pathway Components: tnaCAB_mRNA -> TnaC
Components:
Function Name Type Evidence Reference(s)
product TnaC protein nd nd
reactant tnaCAB_mRNA RNA nd nd
tnaCAB_mRNA TnaA
Name: tnaCAB_mRNA -> TnaA
Description: Translation of TnaA
Type: translation
Pathway Components: tnaCAB_mRNA -> TnaA
Components:
Function Name Type Evidence Reference(s)
product TnaA protein nd nd
reactant tnaCAB_mRNA RNA nd nd
TnaA tryptophan dehydroalanine + indole
Name: tryptophan -> dehydroalanine + indole
Description: Reaction transforming tryptophan into dehydroalanine, indole
Type: state transition
Pathway Components: tryptophan - TnaA -> dehydroalanine + indole
Components:
Function Name Type Evidence Reference(s)
catalyzer TnaA protein nd nd
product dehydroalanine simple_molecule nd nd
product indole simple_molecule nd nd
reactant tryptophan simple_molecule nd nd
TnaA cysteine dehydroalanine + sulfide
Name: cysteine -> dehydroalanine + sulfide
Description: Reaction transforming cysteine into dehydroalanine, sulfide
Type: state transition
Pathway Components: cysteine - TnaA -> dehydroalanine + sulfide
Components:
Function Name Type Evidence Reference(s)
catalyzer TnaA protein nd nd
reactant cysteine simple_molecule nd nd
product dehydroalanine simple_molecule nd nd
product sulfide simple_molecule nd nd
tnaCAB_mRNA TnaB
Name: tnaCAB_mRNA -> TnaB
Description: Translation of TnaB
Type: translation
Pathway Components: tnaCAB_mRNA -> TnaB
Components:
Function Name Type Evidence Reference(s)
product TnaB protein nd nd
reactant tnaCAB_mRNA RNA nd nd
TnaB tryptophan_Ext tryptophan
Name: tryptophan_Ext -> tryptophan
Description: Transport of tryptophan_Ext through a bacterial membrane, leading to the presence of tryptophan inside the cell.
Type: transport
Pathway Components: tryptophan_Ext - TnaB -> tryptophan
Components:
Function Name Type Evidence Reference(s)
catalyzer TnaB protein nd nd
product tryptophan simple_molecule nd nd
reactant tryptophan_Ext simple_molecule nd nd
gadAX_mRNA GadA
Name: gadAX_mRNA -> GadA
Description: Translation of GadA
Type: translation
Pathway Components: gadAX_mRNA -> GadA
Components:
Function Name Type Evidence Reference(s)
product GadA protein nd nd
reactant gadAX_mRNA RNA nd nd
gadAX_mRNA GadX
Name: gadAX_mRNA -> GadX
Description: Translation of GadX
Type: translation
Pathway Components: gadAX_mRNA -> GadX
Components:
Function Name Type Evidence Reference(s)
product GadX protein nd nd
reactant gadAX_mRNA RNA nd nd
tnaC_mRNA TnaC
Name: tnaC_mRNA -> TnaC
Description: Translation of TnaC
Type: translation
Pathway Components: tnaC_mRNA -> TnaC
Components:
Function Name Type Evidence Reference(s)
product TnaC protein nd nd
reactant tnaC_mRNA RNA nd nd



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