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TdcA Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
2-oxobutyrate L-serine L-serine_Ext thr thr_Ext TdcA TdcB TdcC TdcD TdcE TdcF TdcG ac-CoA ammonia CoA formate propanoate propanoyl-P propanoyl-CoA pyruvate tdcABCDEFG tdcABCDEFG_mRNA


Gensor Unit       
Name: TdcA
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0000986 - bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding
GO:0008980 - propionate kinase activity
GO:0006567 - threonine catabolic process
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0016020 - membrane
GO:0006094 - gluconeogenesis
GO:0005622 - intracellular
GO:0003824 - catalytic activity
GO:0015826 - threonine transport
GO:0005887 - integral component of plasma membrane
GO:0016310 - phosphorylation
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Components:
Function Name Type
RNA tdcABCDEFG_mRNA RNA


Reactions       
Showing 16 reactions
tdcABCDEFG tdcABCDEFG_mRNA
Name: tdcABCDEFG -> tdcABCDEFG_mRNA
Description: Transcription of transcription unit tdcABCDEFG; reaction activation by TdcA.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant tdcABCDEFG gene nd nd
product tdcABCDEFG_mRNA RNA nd nd
tdcABCDEFG_mRNA TdcA
Name: tdcABCDEFG_mRNA -> TdcA
Description: Translation of TdcA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant tdcABCDEFG_mRNA RNA nd nd
product TdcA protein nd nd
tdcABCDEFG_mRNA TdcD
Name: tdcABCDEFG_mRNA -> TdcD
Description: Translation of TdcD
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant tdcABCDEFG_mRNA RNA nd nd
product TdcD protein nd nd
propanoate propanoyl-P
Name: propanoate -> propanoyl-P
Description: Reaction transforming propanoate into propanoyl-P
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant propanoate simple molecule nd nd
product propanoyl-P simple molecule nd nd
tdcABCDEFG_mRNA TdcF
Name: tdcABCDEFG_mRNA -> TdcF
Description: Translation of TdcF
Type: translation
Components:
Function Name Type Evidence Reference(s)
product TdcF protein nd nd
reactant tdcABCDEFG_mRNA RNA nd nd
tdcABCDEFG_mRNA TdcC
Name: tdcABCDEFG_mRNA -> TdcC
Description: Translation of TdcC
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant tdcABCDEFG_mRNA RNA nd nd
product TdcC protein nd nd
L-serine_Ext L-serine
Name: L-serine_Ext -> L-serine
Description: Transport of L-serine_Ext through a bacterial membrane, leading to the presence of L-serine inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product L-serine simple molecule nd nd
reactant L-serine_Ext simple molecule nd nd
L-threonine_Ext L-threonine
Name: L-threonine_Ext -> L-threonine
Description: Transport of L-threonine_Ext through a bacterial membrane, leading to the presence of L-threonine inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant L-threonine_Ext simple molecule nd nd
product L-threonine simple molecule nd nd
tdcABCDEFG_mRNA TdcB
Name: tdcABCDEFG_mRNA -> TdcB
Description: Translation of TdcB
Type: translation
Components:
Function Name Type Evidence Reference(s)
product TdcB protein nd nd
reactant tdcABCDEFG_mRNA RNA nd nd
L-serine pyruvate + ammonia
Name: L-serine -> pyruvate + ammonia
Description: Reaction transforming L-serine into pyruvate, ammonia
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product pyruvate simple molecule nd nd
product ammonia simple molecule nd nd
reactant L-serine simple molecule nd nd
L-threonine 2-oxobutyrate + ammonia
Name: L-threonine -> 2-oxobutyrate + ammonia
Description: Reaction transforming L-threonine into 2-oxobutyrate, ammonia
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product ammonia simple molecule nd nd
product 2-oxobutyrate simple molecule nd nd
reactant L-threonine simple molecule nd nd
tdcABCDEFG_mRNA TdcE
Name: tdcABCDEFG_mRNA -> TdcE
Description: Translation of TdcE
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant tdcABCDEFG_mRNA RNA nd nd
product TdcE protein nd nd
2-oxobutyrate + CoA propanoyl-CoA + formate
Name: 2-oxobutyrate + CoA -> propanoyl-CoA + formate
Description: Reaction transforming 2-oxobutyrate, CoA into propanoyl-CoA, formate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant CoA simple molecule nd nd
product formate simple molecule nd nd
reactant 2-oxobutyrate simple molecule nd nd
product propanoyl-CoA simple molecule nd nd
formate + ac-CoA pyruvate + CoA
Name: formate + ac-CoA -> pyruvate + CoA
Description: Reaction transforming formate, ac-CoA into pyruvate, CoA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product CoA simple molecule nd nd
product pyruvate simple molecule nd nd
reactant formate simple molecule nd nd
reactant ac-CoA simple molecule nd nd
tdcABCDEFG_mRNA TdcG
Name: tdcABCDEFG_mRNA -> TdcG
Description: Translation of TdcG
Type: translation
Components:
Function Name Type Evidence Reference(s)
product TdcG protein nd nd
reactant tdcABCDEFG_mRNA RNA nd nd
propanoyl-CoA propanoyl-P
Name: propanoyl-CoA -> propanoyl-P
Description: Transformation of propanoyl-CoA into propanoyl-P by one, or two/three reactions not shown.
Type: super-reaction
Components:
Function Name Type Evidence Reference(s)
product propanoyl-P simple molecule nd nd
reactant propanoyl-CoA simple molecule nd nd



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