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SgrR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
ketoglutarate AlaC L-alanine L-glutamate SetA SgrR This Gensor Unit is not yet available SgrT This Gensor Unit is not yet available TbpA ThiP ThiQ alaC alaC_mRNA a-D-Lactose a-D-Lactose_Ext phosphate pyruvate sgrR-sroA-tbpA-thiPQ sgrR-sroA-tbpA-thiPQ_mRNA sgrST-setA sgrST-setA_mRNA thiamin thiamin_Ext ThiQ ThiP TbpA


Gensor Unit       
Name: SgrR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0045892 - negative regulation of transcription, DNA-templated
GO:0046325 - negative regulation of glucose import
GO:0043190 - ATP-binding cassette (ABC) transporter complex
GO:0003824 - catalytic activity
GO:0009401 - phosphoenolpyruvate-dependent sugar phosphotransferase system
GO:0016020 - membrane
GO:0042597 - periplasmic space
GO:0005737 - cytoplasm
GO:0016887 - ATPase activity
GO:0055085 - transmembrane transport
GO:0045893 - positive regulation of transcription, DNA-templated
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Components:
Function Name Type
simple molecule thiamin_Ext simple molecule


Reactions       
Showing 16 reactions
alaC alaC_mRNA
Name: alaC -> alaC_mRNA
Description: Transcription of transcription unit alaC; reaction activation by SgrR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant alaC gene nd nd
product alaC_mRNA RNA nd nd
sgrR-sroA-tbpA-thiPQ sgrR-sroA-tbpA-thiPQ_mRNA
Name: sgrR-sroA-tbpA-thiPQ -> sgrR-sroA-tbpA-thiPQ_mRNA
Description: Transcription of transcription unit sgrR-sroA-tbpA-thiPQ; reaction inhibition by SgrR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant sgrR-sroA-tbpA-thiPQ gene nd nd
product sgrR-sroA-tbpA-thiPQ_mRNA RNA nd nd
sgrST-setA sgrST-setA_mRNA
Name: sgrST-setA -> sgrST-setA_mRNA
Description: Transcription of transcription unit sgrST-setA; reaction inhibition by Cra.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product sgrST-setA_mRNA RNA nd nd
reactant sgrST-setA gene nd nd
sgrR-sroA-tbpA-thiPQ_mRNA ThiQ
Name: sgrR-sroA-tbpA-thiPQ_mRNA -> ThiQ
Description: Translation of ThiQ
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant sgrR-sroA-tbpA-thiPQ_mRNA RNA nd nd
product ThiQ protein nd nd
ThiQ + ThiP + TbpA ThiQ-ThiP-TbpA
Name: ThiQ + ThiP + TbpA -> ThiQ-ThiP-TbpA
Description: Reaction transforming ThiQ, ThiP, TbpA into ThiQ-ThiP-TbpA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product ThiQ-ThiP-TbpA complex nd nd
reactant ThiQ protein nd nd
reactant ThiP protein nd nd
reactant TbpA protein nd nd
thiamin_Ext phosphate + thiamin
Name: thiamin_Ext -> phosphate + thiamin
Description: Transport of thiamin_Ext through a bacterial membrane, leading to the presence of phosphate, thiamin inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product thiamin simple molecule nd nd
product phosphate simple molecule nd nd
reactant thiamin_Ext simple molecule nd nd
sgrR-sroA-tbpA-thiPQ_mRNA TbpA
Name: sgrR-sroA-tbpA-thiPQ_mRNA -> TbpA
Description: Translation of TbpA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product TbpA protein nd nd
reactant sgrR-sroA-tbpA-thiPQ_mRNA RNA nd nd
sgrST-setA_mRNA SgrT
Name: sgrST-setA_mRNA -> SgrT
Description: Translation of SgrT
Type: translation
Components:
Function Name Type Evidence Reference(s)
product SgrT protein nd nd
reactant sgrST-setA_mRNA RNA nd nd
alaC_mRNA AlaC
Name: alaC_mRNA -> AlaC
Description: Translation of AlaC
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant alaC_mRNA RNA nd nd
product AlaC protein nd nd
ketoglutarate + ala L-glutamate + pyruvate
Name: ketoglutarate + ala -> L-glutamate + pyruvate
Description: Reaction transforming ketoglutarate, ala into L-glutamate, pyruvate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product L-glutamate simple molecule nd nd
reactant ala simple molecule nd nd
product pyruvate simple molecule nd nd
reactant ketoglutarate simple molecule nd nd
sgrR-sroA-tbpA-thiPQ_mRNA SgrR
Name: sgrR-sroA-tbpA-thiPQ_mRNA -> SgrR
Description: Translation of SgrR
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant sgrR-sroA-tbpA-thiPQ_mRNA RNA nd nd
product SgrR protein nd nd
sgrST-setA_mRNA SgrS small regulatory RNA
Name: sgrST-setA_mRNA -> SgrS small regulatory RNA
Description: Translation of SgrS small regulatory RNA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product SgrS small regulatory RNA RNA nd nd
reactant sgrST-setA_mRNA RNA nd nd
sgrR-sroA-tbpA-thiPQ_mRNA SroA small RNA
Name: sgrR-sroA-tbpA-thiPQ_mRNA -> SroA small RNA
Description: Translation of SroA small RNA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product SroA small RNA RNA nd nd
reactant sgrR-sroA-tbpA-thiPQ_mRNA RNA nd nd
sgrR-sroA-tbpA-thiPQ_mRNA ThiP
Name: sgrR-sroA-tbpA-thiPQ_mRNA -> ThiP
Description: Translation of ThiP
Type: translation
Components:
Function Name Type Evidence Reference(s)
product ThiP protein nd nd
reactant sgrR-sroA-tbpA-thiPQ_mRNA RNA nd nd
sgrST-setA_mRNA SetA
Name: sgrST-setA_mRNA -> SetA
Description: Translation of SetA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant sgrST-setA_mRNA RNA nd nd
product SetA protein nd nd
a-D-lactose_Ext a-D-lactose
Name: a-D-lactose_Ext -> a-D-lactose
Description: Transport of a-D-lactose_Ext through a bacterial membrane, leading to the presence of a-D-lactose inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant a-D-lactose_Ext simple molecule nd nd
product a-D-lactose simple molecule nd nd



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