RegulonDB RegulonDB

SgrR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
ketoglutarate AlaC L-alanine L-glutamate SetA SgrR This Gensor Unit is not yet available SgrT This Gensor Unit is not yet available TbpA ThiP ThiQ alaC alaC_mRNA a-D-Lactose a-D-Lactose_Ext phosphate pyruvate sgrR-sroA-tbpA-thiPQ sgrR-sroA-tbpA-thiPQ_mRNA sgrST-setA sgrST-setA_mRNA thiamin thiamin_Ext ThiQ ThiP TbpA


Gensor Unit       
Name: SgrR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:0030632 - D-alanine biosynthetic process
GO:0019272 - L-alanine biosynthetic process from pyruvate
GO:0006523 - alanine biosynthetic process
GO:0034219 - carbohydrate transmembrane transport
GO:0036448 - cellular response to glucose-phosphate stress
GO:0015767 - lactose transport
Read more >
cellular_component GO:0043190 - ATP-binding cassette (ABC) transporter complex
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0016020 - membrane
GO:0030288 - outer membrane-bounded periplasmic space
GO:0005886 - plasma membrane
molecular_function GO:0005524 - ATP binding
GO:0004021 - L-alanine:2-oxoglutarate aminotransferase activity
GO:0000984 - bacterial-type RNA polymerase regulatory region sequence-specific DNA binding
GO:0004857 - enzyme inhibitor activity
GO:0030975 - thiamine binding
GO:0030976 - thiamine pyrophosphate binding
GO:0015234 - thiamine transmembrane transporter activity
Read more >
Components: Show/Hide Components Table (24 more...)
Function Name Type
protein AlaC protein
simple_molecule L-glutamate simple_molecule
protein RNA:SgrS protein
protein RNA:SroA protein
protein SetA protein
protein SgrR protein
protein SgrT protein
protein TbpA protein
protein ThiP protein
protein ThiQ protein
complex ThiQ-ThiP-TbpA complex
gene alaC gene
RNA alaC_mRNA RNA
simple_molecule alanine simple_molecule
simple_molecule ketoglutarate simple_molecule
simple_molecule lactose simple_molecule
simple_molecule lactose_Ext simple_molecule
simple_molecule pyruvate simple_molecule
gene sgrR-sroA-tbpA-thiPQ gene
RNA sgrR-sroA-tbpA-thiPQ_mRNA RNA
gene sgrST-setA gene
RNA sgrST-setA_mRNA RNA
simple_molecule thiamin simple_molecule
simple_molecule thiamin_Ext simple_molecule


Reactions       
Showing 16 reactions
SgrR alaC alaC_mRNA
Name: alaC -> alaC_mRNA
Description: Transcription of transcription unit alaC. Reaction activation by SgrR.
Type: transcription
Pathway Components: alaC - SgrR -> alaC_mRNA
Components:
Function Name Type Evidence Reference(s)
activator SgrR protein nd nd
reactant alaC gene nd nd
product alaC_mRNA RNA nd nd
SgrR sgrR-sroA-tbpA-thiPQ sgrR-sroA-tbpA-thiPQ_mRNA
Name: sgrR-sroA-tbpA-thiPQ -> sgrR-sroA-tbpA-thiPQ_mRNA
Description: Transcription of transcription unit sgrR-sroA-tbpA-thiPQ. Reaction inhibition by SgrR.
Type: transcription
Pathway Components: sgrR-sroA-tbpA-thiPQ - SgrR -> sgrR-sroA-tbpA-thiPQ_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor SgrR protein nd nd
reactant sgrR-sroA-tbpA-thiPQ gene nd nd
product sgrR-sroA-tbpA-thiPQ_mRNA RNA nd nd
SgrR sgrST-setA sgrST-setA_mRNA
Name: sgrST-setA -> sgrST-setA_mRNA
Description: Transcription of transcription unit sgrST-setA. Reaction activation by SgrR.
Type: transcription
Pathway Components: sgrST-setA - SgrR -> sgrST-setA_mRNA
Components:
Function Name Type Evidence Reference(s)
activator SgrR protein nd nd
reactant sgrST-setA gene nd nd
product sgrST-setA_mRNA RNA nd nd
alaC_mRNA AlaC
Name: alaC_mRNA -> AlaC
Description: Translation of AlaC
Type: translation
Pathway Components: alaC_mRNA -> AlaC
Components:
Function Name Type Evidence Reference(s)
product AlaC protein nd nd
reactant alaC_mRNA RNA nd nd
AlaC ketoglutarate + alanine L-glutamate + pyruvate
Name: ketoglutarate + alanine -> L-glutamate + pyruvate
Description: Reaction transforming ketoglutarate, alanine into L-glutamate, pyruvate
Type: state transition
Pathway Components: ketoglutarate + alanine - AlaC -> L-glutamate + pyruvate
Components:
Function Name Type Evidence Reference(s)
catalyzer AlaC protein nd nd
product L-glutamate simple_molecule nd nd
reactant alanine simple_molecule nd nd
reactant ketoglutarate simple_molecule nd nd
product pyruvate simple_molecule nd nd
sgrR-sroA-tbpA-thiPQ_mRNA SgrR
Name: sgrR-sroA-tbpA-thiPQ_mRNA -> SgrR
Description: Translation of SgrR
Type: translation
Pathway Components: sgrR-sroA-tbpA-thiPQ_mRNA -> SgrR
Components:
Function Name Type Evidence Reference(s)
product SgrR protein nd nd
reactant sgrR-sroA-tbpA-thiPQ_mRNA RNA nd nd
sgrR-sroA-tbpA-thiPQ_mRNA RNA:SroA
Name: sgrR-sroA-tbpA-thiPQ_mRNA -> RNA:SroA
Description: Translation of RNA:SroA
Type: translation
Pathway Components: sgrR-sroA-tbpA-thiPQ_mRNA -> RNA:SroA
Components:
Function Name Type Evidence Reference(s)
product RNA:SroA protein nd nd
reactant sgrR-sroA-tbpA-thiPQ_mRNA RNA nd nd
sgrR-sroA-tbpA-thiPQ_mRNA TbpA
Name: sgrR-sroA-tbpA-thiPQ_mRNA -> TbpA
Description: Translation of TbpA
Type: translation
Pathway Components: sgrR-sroA-tbpA-thiPQ_mRNA -> TbpA
Components:
Function Name Type Evidence Reference(s)
product TbpA protein nd nd
reactant sgrR-sroA-tbpA-thiPQ_mRNA RNA nd nd
ThiP + TbpA + ThiQ ThiQ-ThiP-TbpA
Name: ThiP + TbpA + ThiQ -> ThiQ-ThiP-TbpA
Description: Reaction transforming ThiP, TbpA, ThiQ into ThiQ-ThiP-TbpA
Type: state transition
Pathway Components: ThiP + TbpA + ThiQ -> ThiQ-ThiP-TbpA
Components:
Function Name Type Evidence Reference(s)
reactant TbpA protein nd nd
reactant ThiP protein nd nd
reactant ThiQ protein nd nd
product ThiQ-ThiP-TbpA complex nd nd
ThiQ-ThiP-TbpA thiamin_Ext thiamin
Name: thiamin_Ext -> thiamin
Description: Transport of thiamin_Ext through a bacterial membrane, leading to the presence of thiamin inside the cell.
Type: transport
Pathway Components: thiamin_Ext - ThiQ-ThiP-TbpA -> thiamin
Components:
Function Name Type Evidence Reference(s)
catalyzer ThiQ-ThiP-TbpA complex nd nd
product thiamin simple_molecule nd nd
reactant thiamin_Ext simple_molecule nd nd
sgrR-sroA-tbpA-thiPQ_mRNA ThiP
Name: sgrR-sroA-tbpA-thiPQ_mRNA -> ThiP
Description: Translation of ThiP
Type: translation
Pathway Components: sgrR-sroA-tbpA-thiPQ_mRNA -> ThiP
Components:
Function Name Type Evidence Reference(s)
product ThiP protein nd nd
reactant sgrR-sroA-tbpA-thiPQ_mRNA RNA nd nd
sgrR-sroA-tbpA-thiPQ_mRNA ThiQ
Name: sgrR-sroA-tbpA-thiPQ_mRNA -> ThiQ
Description: Translation of ThiQ
Type: translation
Pathway Components: sgrR-sroA-tbpA-thiPQ_mRNA -> ThiQ
Components:
Function Name Type Evidence Reference(s)
product ThiQ protein nd nd
reactant sgrR-sroA-tbpA-thiPQ_mRNA RNA nd nd
sgrST-setA_mRNA RNA:SgrS
Name: sgrST-setA_mRNA -> RNA:SgrS
Description: Translation of RNA:SgrS
Type: translation
Pathway Components: sgrST-setA_mRNA -> RNA:SgrS
Components:
Function Name Type Evidence Reference(s)
product RNA:SgrS protein nd nd
reactant sgrST-setA_mRNA RNA nd nd
sgrST-setA_mRNA SgrT
Name: sgrST-setA_mRNA -> SgrT
Description: Translation of SgrT
Type: translation
Pathway Components: sgrST-setA_mRNA -> SgrT
Components:
Function Name Type Evidence Reference(s)
product SgrT protein nd nd
reactant sgrST-setA_mRNA RNA nd nd
sgrST-setA_mRNA SetA
Name: sgrST-setA_mRNA -> SetA
Description: Translation of SetA
Type: translation
Pathway Components: sgrST-setA_mRNA -> SetA
Components:
Function Name Type Evidence Reference(s)
product SetA protein nd nd
reactant sgrST-setA_mRNA RNA nd nd
SetA lactose_Ext lactose
Name: lactose_Ext -> lactose
Description: Transport of lactose_Ext through a bacterial membrane, leading to the presence of lactose inside the cell.
Type: transport
Pathway Components: lactose_Ext - SetA -> lactose
Components:
Function Name Type Evidence Reference(s)
catalyzer SetA protein nd nd
product lactose simple_molecule nd nd
reactant lactose_Ext simple_molecule nd nd



RegulonDB