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RstA Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
Asr CsgD CsgE CsgF CsgG NarG NarH NarI NarJ OmpF phosphate RstA a menaquinol_Ext menaquinone asr asr_mRNA csgDEFG csgDEFG_mRNA CsgA CsgA_Ext glycine betaine glycine betaine_Ext hydrophilic solute or ion hydrophilic solute or ion_Ext narGHJI narGHJI_mRNA nitrate_Ext nitrite ompF ompF_mRNA RstA phosphate CsgG CsgE CsgF NarG NarH NarI


Gensor Unit       
Name: RstA
Classification:
Groups: GUs related to the two-component system
Gene Ontology Terms (GO): biological_process GO:0019645 - anaerobic electron transport chain
GO:0009061 - anaerobic respiration
GO:0043213 - bacteriocin transport
GO:0022610 - biological adhesion
GO:0051131 - chaperone-mediated protein complex assembly
GO:0006855 - drug transmembrane transport
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cellular_component GO:0044799 - NarGHI complex
GO:0009279 - cell outer membrane
GO:0005737 - cytoplasm
GO:0005887 - integral component of plasma membrane
GO:0031224 - intrinsic component of membrane
GO:0031246 - intrinsic component of periplasmic side of cell outer membrane
GO:0031235 - intrinsic component of the cytoplasmic side of the plasma membrane
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molecular_function GO:0051538 - 3 iron, 4 sulfur cluster binding
GO:0051539 - 4 iron, 4 sulfur cluster binding
GO:0000986 - bacterial-type proximal promoter sequence-specific DNA binding
GO:0042912 - colicin transmembrane transporter activity
GO:0015238 - drug transmembrane transporter activity
GO:0009055 - electron transfer activity
GO:0020037 - heme binding
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Components: Show/Hide Components Table (67 more...)
Function Name Type
simple_molecule 5-methylthioribose simple_molecule
simple_molecule 5-methylthioribose_Ext simple_molecule
simple_molecule A(H2) simple_molecule
protein Asr protein
simple_molecule CO2 simple_molecule
simple_molecule CO2_Ext simple_molecule
simple_molecule CsgA simple_molecule
simple_molecule CsgA_Ext simple_molecule
protein CsgD protein
protein CsgE protein
complex CsgE-CsgG complex
protein CsgF protein
protein CsgG protein
simple_molecule N-acetylneuraminate simple_molecule
simple_molecule N-acetylneuraminate_Ext simple_molecule
protein NarG protein
complex NarG-NarH-NarI complex
protein NarH protein
protein NarI protein
protein NarJ protein
protein OmpF protein
protein RstA protein
complex RstA-phosphate complex
simple_molecule Te0 simple_molecule
simple_molecule TeO2 simple_molecule
protein TolB protein
complex TolB-OmpF complex
simple_molecule acceptors simple_molecule
simple_molecule amino acid simple_molecule
simple_molecule amino acid_Ext simple_molecule
gene asr gene
RNA asr_mRNA RNA
simple_molecule base(2) simple_molecule
simple_molecule base(2)_Ext simple_molecule
simple_molecule beta-Neu5Ac simple_molecule
simple_molecule beta-Neu5Ac_Ext simple_molecule
simple_molecule betaine simple_molecule
simple_molecule betaine_Ext simple_molecule
gene csgDEFG gene
RNA csgDEFG_mRNA RNA
simple_molecule hydrophilic solute or ion 600 Da simple_molecule
simple_molecule hydrophilic solute or ion 600 Da_Ext simple_molecule
simple_molecule inositol simple_molecule
simple_molecule inositol_Ext simple_molecule
simple_molecule ion simple_molecule
simple_molecule ion_Ext simple_molecule
simple_molecule menaquinol_Ext simple_molecule
simple_molecule monosaccharide simple_molecule
simple_molecule monosaccharide_Ext simple_molecule
gene narGHJI gene
RNA narGHJI_mRNA RNA
simple_molecule nitrate_Ext simple_molecule
simple_molecule nitrite simple_molecule
gene ompF gene
RNA ompF_mRNA RNA
simple_molecule organosulfur compound simple_molecule
simple_molecule organosulfur compound_Ext simple_molecule
simple_molecule phosphate simple_molecule
simple_molecule polyol simple_molecule
simple_molecule polyol_Ext simple_molecule
simple_molecule short-chain acid anion simple_molecule
simple_molecule short-chain acid anion_Ext simple_molecule
simple_molecule short-chain alcohol simple_molecule
simple_molecule short-chain alcohol_Ext simple_molecule
simple_molecule ubiquinol_Ext simple_molecule
simple_molecule ubiquinone simple_molecule
simple_molecule vitamin K2 simple_molecule


Reactions       
Showing 37 reactions
phosphate + RstA RstA-phosphate
Name: phosphate + RstA -> RstA-phosphate
Description: Reaction transforming phosphate, RstA into RstA-phosphate
Type: state transition
Pathway Components: phosphate + RstA -> RstA-phosphate
Components:
Function Name Type Evidence Reference(s)
reactant RstA protein nd nd
product RstA-phosphate complex nd nd
reactant phosphate simple_molecule nd nd
RstA-phosphate asr asr_mRNA
Name: asr -> asr_mRNA
Description: Transcription of transcription unit asr. Reaction activation by RstA-phosphate.
Type: transcription
Pathway Components: asr - RstA-phosphate -> asr_mRNA
Components:
Function Name Type Evidence Reference(s)
activator RstA-phosphate complex nd nd
reactant asr gene nd nd
product asr_mRNA RNA nd nd
RstA-phosphate narGHJI narGHJI_mRNA
Name: narGHJI -> narGHJI_mRNA
Description: Transcription of transcription unit narGHJI. Reaction activation by RstA-phosphate.
Type: transcription
Pathway Components: narGHJI - RstA-phosphate -> narGHJI_mRNA
Components:
Function Name Type Evidence Reference(s)
activator RstA-phosphate complex nd nd
reactant narGHJI gene nd nd
product narGHJI_mRNA RNA nd nd
RstA-phosphate csgDEFG csgDEFG_mRNA
Name: csgDEFG -> csgDEFG_mRNA
Description: Transcription of transcription unit csgDEFG. Reaction inhibition by RstA-phosphate.
Type: transcription
Pathway Components: csgDEFG - RstA-phosphate -> csgDEFG_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor RstA-phosphate complex nd nd
reactant csgDEFG gene nd nd
product csgDEFG_mRNA RNA nd nd
RstA-phosphate ompF ompF_mRNA
Name: ompF -> ompF_mRNA
Description: Transcription of transcription unit ompF. Reaction inhibition by RstA-phosphate.
Type: transcription
Pathway Components: ompF - RstA-phosphate -> ompF_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor RstA-phosphate complex nd nd
reactant ompF gene nd nd
product ompF_mRNA RNA nd nd
csgDEFG_mRNA CsgD
Name: csgDEFG_mRNA -> CsgD
Description: Translation of CsgD
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgD
Components:
Function Name Type Evidence Reference(s)
product CsgD protein nd nd
reactant csgDEFG_mRNA RNA nd nd
csgDEFG_mRNA CsgE
Name: csgDEFG_mRNA -> CsgE
Description: Translation of CsgE
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgE
Components:
Function Name Type Evidence Reference(s)
product CsgE protein nd nd
reactant csgDEFG_mRNA RNA nd nd
CsgG + CsgE CsgE-CsgG
Name: CsgG + CsgE -> CsgE-CsgG
Description: Reaction transforming CsgG, CsgE into CsgE-CsgG
Type: state transition
Pathway Components: CsgG + CsgE -> CsgE-CsgG
Components:
Function Name Type Evidence Reference(s)
reactant CsgE protein nd nd
product CsgE-CsgG complex nd nd
reactant CsgG protein nd nd
CsgE-CsgG CsgA_Ext CsgA
Name: CsgA_Ext -> CsgA
Description: Transport of CsgA_Ext through a bacterial membrane, leading to the presence of CsgA inside the cell.
Type: transport
Pathway Components: CsgA_Ext - CsgE-CsgG -> CsgA
Components:
Function Name Type Evidence Reference(s)
product CsgA simple_molecule nd nd
reactant CsgA_Ext simple_molecule nd nd
catalyzer CsgE-CsgG complex nd nd
csgDEFG_mRNA CsgF
Name: csgDEFG_mRNA -> CsgF
Description: Translation of CsgF
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgF
Components:
Function Name Type Evidence Reference(s)
product CsgF protein nd nd
reactant csgDEFG_mRNA RNA nd nd
csgDEFG_mRNA CsgG
Name: csgDEFG_mRNA -> CsgG
Description: Translation of CsgG
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgG
Components:
Function Name Type Evidence Reference(s)
product CsgG protein nd nd
reactant csgDEFG_mRNA RNA nd nd
ompF_mRNA OmpF
Name: ompF_mRNA -> OmpF
Description: Translation of OmpF
Type: translation
Pathway Components: ompF_mRNA -> OmpF
Components:
Function Name Type Evidence Reference(s)
product OmpF protein nd nd
reactant ompF_mRNA RNA nd nd
OmpF 5-methylthioribose_Ext 5-methylthioribose
Name: 5-methylthioribose_Ext -> 5-methylthioribose
Description: Transport of 5-methylthioribose_Ext through a bacterial membrane, leading to the presence of 5-methylthioribose inside the cell.
Type: transport
Pathway Components: 5-methylthioribose_Ext - OmpF -> 5-methylthioribose
Components:
Function Name Type Evidence Reference(s)
product 5-methylthioribose simple_molecule nd nd
reactant 5-methylthioribose_Ext simple_molecule nd nd
catalyzer OmpF protein nd nd
OmpF inositol_Ext inositol
Name: inositol_Ext -> inositol
Description: Transport of inositol_Ext through a bacterial membrane, leading to the presence of inositol inside the cell.
Type: transport
Pathway Components: inositol_Ext - OmpF -> inositol
Components:
Function Name Type Evidence Reference(s)
catalyzer OmpF protein nd nd
product inositol simple_molecule nd nd
reactant inositol_Ext simple_molecule nd nd
OmpF amino acid_Ext amino acid
Name: amino acid_Ext -> amino acid
Description: Transport of amino acid_Ext through a bacterial membrane, leading to the presence of amino acid inside the cell.
Type: transport
Pathway Components: amino acid_Ext - OmpF -> amino acid
Components:
Function Name Type Evidence Reference(s)
catalyzer OmpF protein nd nd
product amino acid simple_molecule nd nd
reactant amino acid_Ext simple_molecule nd nd
OmpF base(2)_Ext base(2)
Name: base(2)_Ext -> base(2)
Description: Transport of base(2)_Ext through a bacterial membrane, leading to the presence of base(2) inside the cell.
Type: transport
Pathway Components: base(2)_Ext - OmpF -> base(2)
Components:
Function Name Type Evidence Reference(s)
catalyzer OmpF protein nd nd
product base(2) simple_molecule nd nd
reactant base(2)_Ext simple_molecule nd nd
OmpF polyol_Ext polyol
Name: polyol_Ext -> polyol
Description: Transport of polyol_Ext through a bacterial membrane, leading to the presence of polyol inside the cell.
Type: transport
Pathway Components: polyol_Ext - OmpF -> polyol
Components:
Function Name Type Evidence Reference(s)
catalyzer OmpF protein nd nd
product polyol simple_molecule nd nd
reactant polyol_Ext simple_molecule nd nd
OmpF short-chain alcohol_Ext short-chain alcohol
Name: short-chain alcohol_Ext -> short-chain alcohol
Description: Transport of short-chain alcohol_Ext through a bacterial membrane, leading to the presence of short-chain alcohol inside the cell.
Type: transport
Pathway Components: short-chain alcohol_Ext - OmpF -> short-chain alcohol
Components:
Function Name Type Evidence Reference(s)
catalyzer OmpF protein nd nd
product short-chain alcohol simple_molecule nd nd
reactant short-chain alcohol_Ext simple_molecule nd nd
OmpF short-chain acid anion_Ext short-chain acid anion
Name: short-chain acid anion_Ext -> short-chain acid anion
Description: Transport of short-chain acid anion_Ext through a bacterial membrane, leading to the presence of short-chain acid anion inside the cell.
Type: transport
Pathway Components: short-chain acid anion_Ext - OmpF -> short-chain acid anion
Components:
Function Name Type Evidence Reference(s)
catalyzer OmpF protein nd nd
product short-chain acid anion simple_molecule nd nd
reactant short-chain acid anion_Ext simple_molecule nd nd
OmpF organosulfur compound_Ext organosulfur compound
Name: organosulfur compound_Ext -> organosulfur compound
Description: Transport of organosulfur compound_Ext through a bacterial membrane, leading to the presence of organosulfur compound inside the cell.
Type: transport
Pathway Components: organosulfur compound_Ext - OmpF -> organosulfur compound
Components:
Function Name Type Evidence Reference(s)
catalyzer OmpF protein nd nd
product organosulfur compound simple_molecule nd nd
reactant organosulfur compound_Ext simple_molecule nd nd
OmpF CO2_Ext CO2
Name: CO2_Ext -> CO2
Description: Transport of CO2_Ext through a bacterial membrane, leading to the presence of CO2 inside the cell.
Type: transport
Pathway Components: CO2_Ext - OmpF -> CO2
Components:
Function Name Type Evidence Reference(s)
product CO2 simple_molecule nd nd
reactant CO2_Ext simple_molecule nd nd
catalyzer OmpF protein nd nd
OmpF ion_Ext ion
Name: ion_Ext -> ion
Description: Transport of ion_Ext through a bacterial membrane, leading to the presence of ion inside the cell.
Type: transport
Pathway Components: ion_Ext - OmpF -> ion
Components:
Function Name Type Evidence Reference(s)
catalyzer OmpF protein nd nd
product ion simple_molecule nd nd
reactant ion_Ext simple_molecule nd nd
OmpF monosaccharide_Ext monosaccharide
Name: monosaccharide_Ext -> monosaccharide
Description: Transport of monosaccharide_Ext through a bacterial membrane, leading to the presence of monosaccharide inside the cell.
Type: transport
Pathway Components: monosaccharide_Ext - OmpF -> monosaccharide
Components:
Function Name Type Evidence Reference(s)
catalyzer OmpF protein nd nd
product monosaccharide simple_molecule nd nd
reactant monosaccharide_Ext simple_molecule nd nd
OmpF beta-Neu5Ac_Ext beta-Neu5Ac
Name: beta-Neu5Ac_Ext -> beta-Neu5Ac
Description: Transport of beta-Neu5Ac_Ext through a bacterial membrane, leading to the presence of beta-Neu5Ac inside the cell.
Type: transport
Pathway Components: beta-Neu5Ac_Ext - OmpF -> beta-Neu5Ac
Components:
Function Name Type Evidence Reference(s)
catalyzer OmpF protein nd nd
product beta-Neu5Ac simple_molecule nd nd
reactant beta-Neu5Ac_Ext simple_molecule nd nd
OmpF N-acetylneuraminate_Ext N-acetylneuraminate
Name: N-acetylneuraminate_Ext -> N-acetylneuraminate
Description: Transport of N-acetylneuraminate_Ext through a bacterial membrane, leading to the presence of N-acetylneuraminate inside the cell.
Type: transport
Pathway Components: N-acetylneuraminate_Ext - OmpF -> N-acetylneuraminate
Components:
Function Name Type Evidence Reference(s)
product N-acetylneuraminate simple_molecule nd nd
reactant N-acetylneuraminate_Ext simple_molecule nd nd
catalyzer OmpF protein nd nd
OmpF betaine_Ext betaine
Name: betaine_Ext -> betaine
Description: Transport of betaine_Ext through a bacterial membrane, leading to the presence of betaine inside the cell.
Type: transport
Pathway Components: betaine_Ext - OmpF -> betaine
Components:
Function Name Type Evidence Reference(s)
catalyzer OmpF protein nd nd
product betaine simple_molecule nd nd
reactant betaine_Ext simple_molecule nd nd
OmpF hydrophilic solute or ion 600 Da_Ext hydrophilic solute or ion 600 Da
Name: hydrophilic solute or ion 600 Da_Ext -> hydrophilic solute or ion 600 Da
Description: Transport of hydrophilic solute or ion 600 Da_Ext through a bacterial membrane, leading to the presence of hydrophilic solute or ion 600 Da inside the cell.
Type: transport
Pathway Components: hydrophilic solute or ion 600 Da_Ext - OmpF -> hydrophilic solute or ion 600 Da
Components:
Function Name Type Evidence Reference(s)
catalyzer OmpF protein nd nd
product hydrophilic solute or ion 600 Da simple_molecule nd nd
reactant hydrophilic solute or ion 600 Da_Ext simple_molecule nd nd
TolB + OmpF TolB-OmpF
Name: TolB + OmpF -> TolB-OmpF
Description: Reaction transforming TolB, OmpF into TolB-OmpF
Type: state transition
Pathway Components: TolB + OmpF -> TolB-OmpF
Components:
Function Name Type Evidence Reference(s)
reactant OmpF protein nd nd
reactant TolB protein nd nd
product TolB-OmpF complex nd nd
narGHJI_mRNA NarG
Name: narGHJI_mRNA -> NarG
Description: Translation of NarG
Type: translation
Pathway Components: narGHJI_mRNA -> NarG
Components:
Function Name Type Evidence Reference(s)
product NarG protein nd nd
reactant narGHJI_mRNA RNA nd nd
NarI + NarH + NarG NarG-NarH-NarI
Name: NarI + NarH + NarG -> NarG-NarH-NarI
Description: Reaction transforming NarI, NarH, NarG into NarG-NarH-NarI
Type: state transition
Pathway Components: NarI + NarH + NarG -> NarG-NarH-NarI
Components:
Function Name Type Evidence Reference(s)
reactant NarG protein nd nd
product NarG-NarH-NarI complex nd nd
reactant NarH protein nd nd
reactant NarI protein nd nd
NarG-NarH-NarI menaquinol_Ext + nitrate_Ext vitamin K2 + nitrite
Name: menaquinol_Ext + nitrate_Ext -> vitamin K2 + nitrite
Description: Transport of menaquinol_Ext, nitrate_Ext through a bacterial membrane, leading to the presence of vitamin K2, nitrite inside the cell.
Type: transport
Pathway Components: menaquinol_Ext + nitrate_Ext - NarG-NarH-NarI -> vitamin K2 + nitrite
Components:
Function Name Type Evidence Reference(s)
catalyzer NarG-NarH-NarI complex nd nd
reactant menaquinol_Ext simple_molecule nd nd
reactant nitrate_Ext simple_molecule nd nd
product nitrite simple_molecule nd nd
product vitamin K2 simple_molecule nd nd
NarG-NarH-NarI ubiquinol_Ext + nitrate_Ext ubiquinone + nitrite
Name: ubiquinol_Ext + nitrate_Ext -> ubiquinone + nitrite
Description: Transport of ubiquinol_Ext, nitrate_Ext through a bacterial membrane, leading to the presence of ubiquinone, nitrite inside the cell.
Type: transport
Pathway Components: ubiquinol_Ext + nitrate_Ext - NarG-NarH-NarI -> ubiquinone + nitrite
Components:
Function Name Type Evidence Reference(s)
catalyzer NarG-NarH-NarI complex nd nd
reactant nitrate_Ext simple_molecule nd nd
product nitrite simple_molecule nd nd
reactant ubiquinol_Ext simple_molecule nd nd
product ubiquinone simple_molecule nd nd
NarG-NarH-NarI A(H2) + TeO2 acceptors + Te0
Name: A(H2) + TeO2 -> acceptors + Te0
Description: Reaction transforming A(H2), TeO2 into acceptors, Te0
Type: state transition
Pathway Components: A(H2) + TeO2 - NarG-NarH-NarI -> acceptors + Te0
Components:
Function Name Type Evidence Reference(s)
reactant A(H2) simple_molecule nd nd
catalyzer NarG-NarH-NarI complex nd nd
product Te0 simple_molecule nd nd
reactant TeO2 simple_molecule nd nd
product acceptors simple_molecule nd nd
narGHJI_mRNA NarH
Name: narGHJI_mRNA -> NarH
Description: Translation of NarH
Type: translation
Pathway Components: narGHJI_mRNA -> NarH
Components:
Function Name Type Evidence Reference(s)
product NarH protein nd nd
reactant narGHJI_mRNA RNA nd nd
narGHJI_mRNA NarJ
Name: narGHJI_mRNA -> NarJ
Description: Translation of NarJ
Type: translation
Pathway Components: narGHJI_mRNA -> NarJ
Components:
Function Name Type Evidence Reference(s)
product NarJ protein nd nd
reactant narGHJI_mRNA RNA nd nd
narGHJI_mRNA NarI
Name: narGHJI_mRNA -> NarI
Description: Translation of NarI
Type: translation
Pathway Components: narGHJI_mRNA -> NarI
Components:
Function Name Type Evidence Reference(s)
product NarI protein nd nd
reactant narGHJI_mRNA RNA nd nd
asr_mRNA Asr
Name: asr_mRNA -> Asr
Description: Translation of Asr
Type: translation
Pathway Components: asr_mRNA -> Asr
Components:
Function Name Type Evidence Reference(s)
product Asr protein nd nd
reactant asr_mRNA RNA nd nd



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