RegulonDB RegulonDB

RtcR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
GMP GTP RtcA RtcB RtcR a 5' adenylylated polynucleotide a 5'-hydroxyl terminated RNA a 5'-phosphopolynucleotide a ligated RNA PP rtcBA rtcBA_mRNA 3-Prime-Phosphate-Terminated-RNAs Cyclic-Phosphate-Terminated-RNAs


Gensor Unit       
Name: RtcR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:0006266 - DNA ligation
GO:0006281 - DNA repair
GO:0006396 - RNA processing
GO:0042245 - RNA repair
GO:0006974 - cellular response to DNA damage stimulus
molecular_function GO:0003909 - DNA ligase activity
GO:0008452 - RNA ligase activity
GO:0003963 - RNA-3'-phosphate cyclase activity
GO:0016874 - ligase activity
GO:0030145 - manganese ion binding
GO:0046872 - metal ion binding
Components: Show/Hide Components Table (14 more...)
Function Name Type
simple_molecule 5' adenylylated polynucleotide simple_molecule
simple_molecule 5'-hydroxyl terminated RNA simple_molecule
simple_molecule 5'-phosphopolynucleotide simple_molecule
simple_molecule RNA 3'-terminal-phosphate simple_molecule
simple_molecule RNA terminal-2',3'-cyclic-phosphate simple_molecule
protein RtcA protein
protein RtcB protein
protein RtcR protein
simple_molecule diphosphate simple_molecule
simple_molecule guanosine-triphosphate simple_molecule
simple_molecule guanylate simple_molecule
simple_molecule ligated RNA simple_molecule
gene rtcBA gene
RNA rtcBA_mRNA RNA


Reactions       
Showing 6 reactions
RtcR rtcBA rtcBA_mRNA
Name: rtcBA -> rtcBA_mRNA
Description: Transcription of transcription unit rtcBA. Reaction activation by RtcR.
Type: transcription
Pathway Components: rtcBA - RtcR -> rtcBA_mRNA
Components:
Function Name Type Evidence Reference(s)
activator RtcR protein nd nd
reactant rtcBA gene nd nd
product rtcBA_mRNA RNA nd nd
rtcBA_mRNA RtcB
Name: rtcBA_mRNA -> RtcB
Description: Translation of RtcB
Type: translation
Pathway Components: rtcBA_mRNA -> RtcB
Components:
Function Name Type Evidence Reference(s)
product RtcB protein nd nd
reactant rtcBA_mRNA RNA nd nd
RtcB Reactants diphosphate + ligated RNA + guanylate
Name: RNA terminal-2',3'-cyclic-phosphate + 5'-hydroxyl terminated RNA + guanosine-triphosphate -> diphosphate + ligated RNA + guanylate
Description: Reaction transforming RNA terminal-2',3'-cyclic-phosphate, 5'-hydroxyl terminated RNA, guanosine-triphosphate into diphosphate, ligated RNA , guanylate
Type: state transition
Pathway Components: RNA terminal-2',3'-cyclic-phosphate + 5'-hydroxyl terminated RNA + guanosine-triphosphate - RtcB -> diphosphate + ligated RNA + guanylate
Components:
Function Name Type Evidence Reference(s)
reactant 5'-hydroxyl terminated RNA simple_molecule nd nd
reactant RNA terminal-2',3'-cyclic-phosphate simple_molecule nd nd
catalyzer RtcB protein nd nd
product diphosphate simple_molecule nd nd
reactant guanosine-triphosphate simple_molecule nd nd
product guanylate simple_molecule nd nd
product ligated RNA simple_molecule nd nd
rtcBA_mRNA RtcA
Name: rtcBA_mRNA -> RtcA
Description: Translation of RtcA
Type: translation
Pathway Components: rtcBA_mRNA -> RtcA
Components:
Function Name Type Evidence Reference(s)
product RtcA protein nd nd
reactant rtcBA_mRNA RNA nd nd
RtcA RNA 3'-terminal-phosphate Products
Name: RNA 3'-terminal-phosphate -> RNA terminal-2',3'-cyclic-phosphate + diphosphate
Description: Reaction transforming RNA 3'-terminal-phosphate into RNA terminal-2',3'-cyclic-phosphate, diphosphate
Type: state transition
Pathway Components: RNA 3'-terminal-phosphate - RtcA -> RNA terminal-2',3'-cyclic-phosphate + diphosphate
Components:
Function Name Type Evidence Reference(s)
reactant RNA 3'-terminal-phosphate simple_molecule nd nd
product RNA terminal-2',3'-cyclic-phosphate simple_molecule nd nd
catalyzer RtcA protein nd nd
product diphosphate simple_molecule nd nd
RtcA 5'-phosphopolynucleotide 5' adenylylated polynucleotide + diphosphate
Name: 5'-phosphopolynucleotide -> 5' adenylylated polynucleotide + diphosphate
Description: Reaction transforming 5'-phosphopolynucleotide into 5' adenylylated polynucleotide, diphosphate
Type: state transition
Pathway Components: 5'-phosphopolynucleotide - RtcA -> 5' adenylylated polynucleotide + diphosphate
Components:
Function Name Type Evidence Reference(s)
product 5' adenylylated polynucleotide simple_molecule nd nd
reactant 5'-phosphopolynucleotide simple_molecule nd nd
catalyzer RtcA protein nd nd
product diphosphate simple_molecule nd nd



RegulonDB