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RhaR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
L-rhamnose RhaR RhaS rhaSR rhaSR_mRNA RhaR L-rhamnose


Gensor Unit       
Name: RhaR
Description: Molecular biology level
Detailed: In the presence of rhamnose, RhaR positively regulates the expression of genes required to regulate rhamnose utilization. Under these conditions, RhaR is modified to RhaR-rhamnose, binds its target sites enabling its own expression and the expression of its regulated gen, RhaS.
Less detailed: In the presence of rhamnose, RhaR positively regulates the expression of genes needed for regulation of rhamnose utilization.

Physiology level
Detailed: The presence of rhamnose induces the expression of genes necessary for regulation of rhamnose utilization, under this condition these genes are expressed.
Classification:
Groups: GUs related to carbon source utilization
Gene Ontology Terms (GO): biological_process GO:0019243 - methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
GO:0006355 - regulation of transcription, DNA-templated
GO:0006351 - transcription, DNA-templated
molecular_function GO:0003700 - DNA binding transcription factor activity
GO:0019172 - glyoxalase III activity
GO:0043565 - sequence-specific DNA binding
Components:
Function Name Type
protein RhaR protein
complex RhaR-rhamnose complex
protein RhaS protein
gene rhaSR gene
RNA rhaSR_mRNA RNA
simple_molecule rhamnose simple_molecule


Reactions       
Showing 4 reactions
rhamnose + RhaR RhaR-rhamnose
Name: rhamnose + RhaR -> RhaR-rhamnose
Description: Reaction transforming rhamnose, RhaR into RhaR-rhamnose
Type: state transition
Pathway Components: rhamnose + RhaR -> RhaR-rhamnose
Components:
Function Name Type Evidence Reference(s)
reactant RhaR protein nd nd
product RhaR-rhamnose complex nd nd
reactant rhamnose simple_molecule nd nd
RhaR-rhamnose rhaSR rhaSR_mRNA
Name: rhaSR -> rhaSR_mRNA
Description: Transcription of transcription unit rhaSR. Reaction activation by RhaR-rhamnose.
Type: transcription
Pathway Components: rhaSR - RhaR-rhamnose -> rhaSR_mRNA
Components:
Function Name Type Evidence Reference(s)
activator RhaR-rhamnose complex nd nd
reactant rhaSR gene nd nd
product rhaSR_mRNA RNA nd nd
rhaSR_mRNA RhaS
Name: rhaSR_mRNA -> RhaS
Description: Translation of RhaS
Type: translation
Pathway Components: rhaSR_mRNA -> RhaS
Components:
Function Name Type Evidence Reference(s)
product RhaS protein nd nd
reactant rhaSR_mRNA RNA nd nd
rhaSR_mRNA RhaR
Name: rhaSR_mRNA -> RhaR
Description: Translation of RhaR
Type: translation
Pathway Components: rhaSR_mRNA -> RhaR
Components:
Function Name Type Evidence Reference(s)
product RhaR protein nd nd
reactant rhaSR_mRNA RNA nd nd



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