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RhaR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
isodulcit rhaSR rhaSR_mRNA RhaR isodulcit RhaR RhaS


Gensor Unit       
Name: RhaR
Description: Molecular biology level
Detailed: In the presence of rhamnose, RhaR positively regulates the expression of genes required to regulate rhamnose utilization. Under these conditions, RhaR is modified to RhaR-rhamnose, binds its target sites enabling its own expression and the expression of its regulated gen, RhaS.
Less detailed: In the presence of rhamnose, RhaR positively regulates the expression of genes needed for regulation of rhamnose utilization.

Physiology level
Detailed: The presence of rhamnose induces the expression of genes necessary for regulation of rhamnose utilization, under this condition these genes are expressed.
Classification:
Groups: General function prediction only
Gene Ontology Terms (GO): biological_process GO:0045893 - positive regulation of transcription, DNA-templated
GO:0006355 - regulation of transcription, DNA-templated
GO:0019299 - rhamnose metabolic process
GO:0006351 - transcription, DNA-templated
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0043565 - sequence-specific DNA binding
Components:
  Function Name Type
  protein RhaR protein
  complex RhaR-isodulcit complex
  protein RhaS protein
  simple_molecule isodulcit simple_molecule
  gene rhaSR gene
  RNA rhaSR_mRNA RNA


Reactions       
Showing 4 reactions
isodulcit + RhaR RhaR-isodulcit
Name: isodulcit + RhaR -> RhaR-isodulcit
Description: Reaction transforming isodulcit, RhaR into RhaR-isodulcit
Type: state transition
Pathway Components: isodulcit + RhaR -> RhaR-isodulcit
Components:
Function Name Type
reactant RhaR protein
product RhaR-isodulcit complex
reactant isodulcit simple_molecule
RhaR-isodulcit rhaSR rhaSR_mRNA
Name: rhaSR -> rhaSR_mRNA
Description: Transcription of transcription unit rhaSR. Reaction activation by RhaR-isodulcit.
Type: transcription
Pathway Components: rhaSR - RhaR-isodulcit -> rhaSR_mRNA
Components:
Function Name Type
activator RhaR-isodulcit complex
reactant rhaSR gene
product rhaSR_mRNA RNA
rhaSR_mRNA RhaS
Name: rhaSR_mRNA -> RhaS
Description: Translation of RhaS
Type: translation
Pathway Components: rhaSR_mRNA -> RhaS
Components:
Function Name Type
product RhaS protein
reactant rhaSR_mRNA RNA
rhaSR_mRNA RhaR
Name: rhaSR_mRNA -> RhaR
Description: Translation of RhaR
Type: translation
Pathway Components: rhaSR_mRNA -> RhaR
Components:
Function Name Type
product RhaR protein
reactant rhaSR_mRNA RNA



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