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RbsR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
10-formyl-tetrahydrofolate 2'-deoxyadenosine 2'-deoxyinosine AICAR FAICAR PRA Add ribose ribose-5P Imp GAR PurD PurH RbsA RbsB RbsC RbsD RbsK RbsR add add_mRNA adenosine alpha D-ribose ammonium beta-D-ribofuranose beta-D-ribopyranose beta-D-ribopyranose_Ext glycine inosine phosphate purHD purHD_mRNA rbsDACBKR rbsDACBKR_mRNA THF RbsR ribose RbsA RbsC RbsB phosphate


Gensor Unit       
Name: RbsR
Classification:
Groups: GUs related to carbon source utilization
Gene Ontology Terms (GO): GO:0001216 - bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GO:0046103 - inosine biosynthetic process
GO:0000986 - bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding
GO:0015950 - purine nucleotide interconversion
GO:0043190 - ATP-binding cassette (ABC) transporter complex
GO:0009113 - purine nucleobase biosynthetic process
GO:0008270 - zinc ion binding
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0016020 - membrane
GO:0005996 - monosaccharide metabolic process
GO:0003824 - catalytic activity
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Components:
Function Name Type
simple molecule THF simple molecule


Reactions       
Showing 23 reactions
purHD purHD_mRNA
Name: purHD -> purHD_mRNA
Description: Transcription of transcription unit purHD; reaction activation by PhoP-Phosphorylated.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant purHD gene nd nd
product purHD_mRNA RNA nd nd
rbsDACBKR rbsDACBKR_mRNA
Name: rbsDACBKR -> rbsDACBKR_mRNA
Description: Transcription of transcription unit rbsDACBKR; reaction inhibition by RbsR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product rbsDACBKR_mRNA RNA nd nd
reactant rbsDACBKR gene nd nd
RbsR + ribose RbsR-ribose
Name: RbsR + ribose -> RbsR-ribose
Description: Reaction transforming RbsR, ribose into RbsR-ribose
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant ribose simple molecule nd nd
product RbsR-ribose complex nd nd
reactant RbsR protein nd nd
add add_mRNA
Name: add -> add_mRNA
Description: Transcription of transcription unit add; reaction activation by RbsR-ribose.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant add gene nd nd
product add_mRNA RNA nd nd
purHD_mRNA PurD
Name: purHD_mRNA -> PurD
Description: Translation of PurD
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant purHD_mRNA RNA nd nd
product PurD protein nd nd
PRA + glycine phosphate + GAR
Name: PRA + glycine -> phosphate + GAR
Description: Reaction transforming PRA, glycine into phosphate, GAR
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product GAR simple molecule nd nd
product phosphate simple molecule nd nd
reactant glycine simple molecule nd nd
reactant PRA simple molecule nd nd
rbsDACBKR_mRNA RbsR
Name: rbsDACBKR_mRNA -> RbsR
Description: Translation of RbsR
Type: translation
Components:
Function Name Type Evidence Reference(s)
product RbsR protein nd nd
reactant rbsDACBKR_mRNA RNA nd nd
add_mRNA Add
Name: add_mRNA -> Add
Description: Translation of Add
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant add_mRNA RNA nd nd
product Add protein nd nd
deoxyadenosine ammonium + deoxyinosine
Name: deoxyadenosine -> ammonium + deoxyinosine
Description: Reaction transforming deoxyadenosine into ammonium, deoxyinosine
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product ammonium simple molecule nd nd
reactant deoxyadenosine simple molecule nd nd
product deoxyinosine simple molecule nd nd
adenosine ammonium + inosine
Name: adenosine -> ammonium + inosine
Description: Reaction transforming adenosine into ammonium, inosine
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant adenosine simple molecule nd nd
product inosine simple molecule nd nd
product ammonium simple molecule nd nd
rbsDACBKR_mRNA RbsD
Name: rbsDACBKR_mRNA -> RbsD
Description: Translation of RbsD
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant rbsDACBKR_mRNA RNA nd nd
product RbsD protein nd nd
beta-D-ribofuranose beta-D-ribopyranose
Name: beta-D-ribofuranose -> beta-D-ribopyranose
Description: Reaction transforming beta-D-ribofuranose into beta-D-ribopyranose
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product beta-D-ribopyranose simple molecule nd nd
reactant beta-D-ribofuranose simple molecule nd nd
purHD_mRNA PurH
Name: purHD_mRNA -> PurH
Description: Translation of PurH
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PurH protein nd nd
reactant purHD_mRNA RNA nd nd
10-formyl-tetrahydrofolate + AICAR THF + FAICAR
Name: 10-formyl-tetrahydrofolate + AICAR -> THF + FAICAR
Description: Reaction transforming 10-formyl-tetrahydrofolate, AICAR into THF, FAICAR
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant AICAR simple molecule nd nd
product FAICAR simple molecule nd nd
reactant 10-formyl-tetrahydrofolate simple molecule nd nd
product THF simple molecule nd nd
IMP FAICAR
Name: IMP -> FAICAR
Description: Reaction transforming IMP into FAICAR
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product FAICAR simple molecule nd nd
reactant IMP simple molecule nd nd
rbsDACBKR_mRNA RbsC
Name: rbsDACBKR_mRNA -> RbsC
Description: Translation of RbsC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product RbsC protein nd nd
reactant rbsDACBKR_mRNA RNA nd nd
RbsA + RbsC + RbsB RbsA-RbsC-RbsB
Name: RbsA + RbsC + RbsB -> RbsA-RbsC-RbsB
Description: Reaction transforming RbsA, RbsC, RbsB into RbsA-RbsC-RbsB
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant RbsB protein nd nd
reactant RbsA protein nd nd
reactant RbsC protein nd nd
product RbsA-RbsC-RbsB complex nd nd
beta-D-ribopyranose_Ext phosphate + beta-D-ribopyranose
Name: beta-D-ribopyranose_Ext -> phosphate + beta-D-ribopyranose
Description: Transport of beta-D-ribopyranose_Ext through a bacterial membrane, leading to the presence of phosphate, beta-D-ribopyranose inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product phosphate simple molecule nd nd
reactant beta-D-ribopyranose_Ext simple molecule nd nd
product beta-D-ribopyranose simple molecule nd nd
rbsDACBKR_mRNA RbsB
Name: rbsDACBKR_mRNA -> RbsB
Description: Translation of RbsB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant rbsDACBKR_mRNA RNA nd nd
product RbsB protein nd nd
rbsDACBKR_mRNA RbsK
Name: rbsDACBKR_mRNA -> RbsK
Description: Translation of RbsK
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant rbsDACBKR_mRNA RNA nd nd
product RbsK protein nd nd
alpha D-ribose ribose-5P
Name: alpha D-ribose -> ribose-5P
Description: Reaction transforming alpha D-ribose into ribose-5P
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant alpha D-ribose simple molecule nd nd
product ribose-5P simple molecule nd nd
rbsDACBKR_mRNA RbsA
Name: rbsDACBKR_mRNA -> RbsA
Description: Translation of RbsA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product RbsA protein nd nd
reactant rbsDACBKR_mRNA RNA nd nd
beta-D-ribofuranose alpha D-ribose
Name: beta-D-ribofuranose -> alpha D-ribose
Description: Transformation of beta-D-ribofuranose into alpha D-ribose by one, or two/three reactions not shown.
Type: super-reaction
Components:
Function Name Type Evidence Reference(s)
reactant beta-D-ribofuranose simple molecule nd nd
product alpha D-ribose simple molecule nd nd



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