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PuuR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
glutamyl-L-putrescine ketoglutarate 4-glutamylamino-butanal 4-glutamylamino-butanoate GABA L-glutamate PuuA PuuB PuuC PuuD PuuE PuuP PuuR ammonium putrescine putrescine ext puuAP puuDRCBE puuAP mRNA puuDRCBE mRNA succ-S-ald L-glutamate L-glutamate


Gensor Unit       
Name: PuuR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0004356 - glutamate-ammonia ligase activity
GO:0016491 - oxidoreductase activity
GO:0016020 - membrane
GO:0003824 - catalytic activity
GO:0003333 - amino acid transmembrane transport
GO:0034024 - glutamate-putrescine ligase activity
GO:0033969 - gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GO:0055085 - transmembrane transport
GO:0003867 - 4-aminobutyrate transaminase activity
GO:0006541 - glutamine metabolic process
GO:0003677 - DNA binding
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Components:
Function Name Type
simple molecule succ-S-ald simple molecule


Reactions       
Showing 16 reactions
puuAP puuAP_mRNA
Name: puuAP -> puuAP_mRNA
Description: Transcription of transcription unit puuAP; reaction inhibition by PuuR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product puuAP_mRNA RNA nd nd
reactant puuAP gene nd nd
puuDRCBE puuDRCBE_mRNA
Name: puuDRCBE -> puuDRCBE_mRNA
Description: Transcription of transcription unit puuDRCBE; reaction inhibition by PuuR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant puuDRCBE gene nd nd
product puuDRCBE_mRNA RNA nd nd
puuDRCBE_mRNA PuuC
Name: puuDRCBE_mRNA -> PuuC
Description: Translation of PuuC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PuuC protein nd nd
reactant puuDRCBE_mRNA RNA nd nd
3-hydroxypropanal hydracrylic acid
Name: 3-hydroxypropanal -> hydracrylic acid
Description: Reaction transforming 3-hydroxypropanal into hydracrylic acid
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product hydracrylic acid simple molecule nd nd
reactant 3-hydroxypropanal simple molecule nd nd
4-(gamma-glutamylamino)butanal 4-(L-γ-glutamylamino)butanoate
Name: 4-(gamma-glutamylamino)butanal -> 4-(L-γ-glutamylamino)butanoate
Description: Reaction transforming 4-(gamma-glutamylamino)butanal into 4-(L-γ-glutamylamino)butanoate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant 4-(gamma-glutamylamino)butanal simple molecule nd nd
product 4-(L-γ-glutamylamino)butanoate simple molecule nd nd
puuAP_mRNA PuuA
Name: puuAP_mRNA -> PuuA
Description: Translation of PuuA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant puuAP_mRNA RNA nd nd
product PuuA protein nd nd
putrescine + L-glutamate gamma-Glu-Put + phosphate
Name: putrescine + L-glutamate -> gamma-Glu-Put + phosphate
Description: Reaction transforming putrescine, L-glutamate into gamma-Glu-Put, phosphate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant L-glutamate simple molecule nd nd
reactant putrescine simple molecule nd nd
product phosphate simple molecule nd nd
product gamma-Glu-Put simple molecule nd nd
puuAP_mRNA PuuP
Name: puuAP_mRNA -> PuuP
Description: Translation of PuuP
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant puuAP_mRNA RNA nd nd
product PuuP protein nd nd
putrescine_Ext putrescine
Name: putrescine_Ext -> putrescine
Description: Transport of putrescine_Ext through a bacterial membrane, leading to the presence of putrescine inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product putrescine simple molecule nd nd
reactant putrescine_Ext simple molecule nd nd
puuDRCBE_mRNA PuuE
Name: puuDRCBE_mRNA -> PuuE
Description: Translation of PuuE
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PuuE protein nd nd
reactant puuDRCBE_mRNA RNA nd nd
ketoglutarate + GABA L-glutamate + succ-S-ald
Name: ketoglutarate + GABA -> L-glutamate + succ-S-ald
Description: Reaction transforming ketoglutarate, GABA into L-glutamate, succ-S-ald
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product L-glutamate simple molecule nd nd
reactant ketoglutarate simple molecule nd nd
product succ-S-ald simple molecule nd nd
reactant GABA simple molecule nd nd
puuDRCBE_mRNA PuuR
Name: puuDRCBE_mRNA -> PuuR
Description: Translation of PuuR
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant puuDRCBE_mRNA RNA nd nd
product PuuR protein nd nd
puuDRCBE_mRNA PuuB
Name: puuDRCBE_mRNA -> PuuB
Description: Translation of PuuB
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PuuB protein nd nd
reactant puuDRCBE_mRNA RNA nd nd
gamma-Glu-Put + oxygen 4-(gamma-glutamylamino)butanal + perhydrol + ammonium
Name: gamma-Glu-Put + oxygen -> 4-(gamma-glutamylamino)butanal + perhydrol + ammonium
Description: Reaction transforming gamma-Glu-Put, oxygen into 4-(gamma-glutamylamino)butanal, perhydrol , ammonium
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant gamma-Glu-Put simple molecule nd nd
product perhydrol simple molecule nd nd
product 4-(gamma-glutamylamino)butanal simple molecule nd nd
product ammonium simple molecule nd nd
reactant oxygen simple molecule nd nd
puuDRCBE_mRNA PuuD
Name: puuDRCBE_mRNA -> PuuD
Description: Translation of PuuD
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant puuDRCBE_mRNA RNA nd nd
product PuuD protein nd nd
4-(L-γ-glutamylamino)butanoate GABA + L-glutamate
Name: 4-(L-γ-glutamylamino)butanoate -> GABA + L-glutamate
Description: Reaction transforming 4-(L-γ-glutamylamino)butanoate into GABA, L-glutamate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant 4-(L-γ-glutamylamino)butanoate simple molecule nd nd
product L-glutamate simple molecule nd nd
product GABA simple molecule nd nd



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