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PuuR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
ketoglutarate perhydrol PuuC PuuR PuuR putrescine PuuE succinate puuDRCBE_mRNA This Gensor Unit is not yet available GABA puuDRCBE 4-(gamma-glutamylamino)butanal hydracrylic acid PuuD ammonium gamma-glu-GABA gamma-Glu-Put L-glutamate phosphate PuuA PuuB This Gensor Unit is not yet available oxygen ABAL PuuP 3-hydroxypropanal succ-S-ald putrescine_Ext putrescine putrescine


Gensor Unit       
Name: PuuR
Classification:
Groups: Transcription
Energy production and conversion
Amino acid transport and metabolism
Gene Ontology Terms (GO): biological_process GO:0003333 - amino acid transmembrane transport
GO:0006865 - amino acid transport
GO:0006974 - cellular response to DNA damage stimulus
GO:0009448 - gamma-aminobutyric acid metabolic process
GO:0006542 - glutamine biosynthetic process
GO:0008152 - metabolic process
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cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016021 - integral component of membrane
GO:0016020 - membrane
GO:0005886 - plasma membrane
molecular_function GO:0003867 - 4-aminobutyrate transaminase activity
GO:0034386 - 4-aminobutyrate:2-oxoglutarate transaminase activity
GO:0005524 - ATP binding
GO:0003677 - DNA binding
GO:0004030 - aldehyde dehydrogenase [NAD(P)+] activity
GO:0015171 - amino acid transmembrane transporter activity
GO:0003824 - catalytic activity
Read more >
Components:
  Function Name Type
  simple_molecule γ-Glu-Put simple_molecule
  simple_molecule γ-glu-GABA simple_molecule
  simple_molecule 3-hydroxypropanal simple_molecule
  simple_molecule 4-(γ-glutamylamino)butanal simple_molecule
  simple_molecule ABAL simple_molecule
  simple_molecule GABA simple_molecule
  simple_molecule L-glutamate simple_molecule
  protein PuuA protein
  protein PuuB protein
  protein PuuC protein
  protein PuuD protein
  protein PuuE protein
  protein PuuP protein
  protein PuuR protein
  complex PuuR-putrescine complex
  simple_molecule ammonium simple_molecule
  simple_molecule hydracrylic acid simple_molecule
  simple_molecule ketoglutarate simple_molecule
  simple_molecule oxygen simple_molecule
  simple_molecule perhydrol simple_molecule
  simple_molecule phosphate simple_molecule
  simple_molecule putrescine simple_molecule
  simple_molecule putrescine_Ext simple_molecule
  gene puuAP gene
  RNA puuAP_mRNA RNA
  gene puuDRCBE gene
  RNA puuDRCBE_mRNA RNA
  simple_molecule succ-S-ald simple_molecule
  simple_molecule succinate simple_molecule


Reactions       
Showing 20 reactions
PuuR puuAP puuAP_mRNA
Name: puuAP -> puuAP_mRNA
Description: Transcription of transcription unit puuAP. Reaction inhibition by PuuR.
Type: transcription
Pathway Components: puuAP - PuuR -> puuAP_mRNA
Components:
Function Name Type
inhibitor PuuR protein
reactant puuAP gene
product puuAP_mRNA RNA
PuuR puuDRCBE puuDRCBE_mRNA
Name: puuDRCBE -> puuDRCBE_mRNA
Description: Transcription of transcription unit puuDRCBE. Reaction inhibition by PuuR.
Type: transcription
Pathway Components: puuDRCBE - PuuR -> puuDRCBE_mRNA
Components:
Function Name Type
inhibitor PuuR protein
reactant puuDRCBE gene
product puuDRCBE_mRNA RNA
putrescine + PuuR PuuR-putrescine
Name: putrescine + PuuR -> PuuR-putrescine
Description: Reaction transforming putrescine, PuuR into PuuR-putrescine
Type: state transition
Pathway Components: putrescine + PuuR -> PuuR-putrescine
Components:
Function Name Type
reactant PuuR protein
product PuuR-putrescine complex
reactant putrescine simple_molecule
puuAP_mRNA PuuA
Name: puuAP_mRNA -> PuuA
Description: Translation of PuuA
Type: translation
Pathway Components: puuAP_mRNA -> PuuA
Components:
Function Name Type
product PuuA protein
reactant puuAP_mRNA RNA
PuuA L-glutamate + putrescine γ-Glu-Put + phosphate
Name: L-glutamate + putrescine -> γ-Glu-Put + phosphate
Description: Reaction transforming L-glutamate, putrescine into γ-Glu-Put, phosphate
Type: state transition
Pathway Components: L-glutamate + putrescine - PuuA -> γ-Glu-Put + phosphate
Components:
Function Name Type
product γ-Glu-Put simple_molecule
reactant L-glutamate simple_molecule
catalyzer PuuA protein
product phosphate simple_molecule
reactant putrescine simple_molecule
puuAP_mRNA PuuP
Name: puuAP_mRNA -> PuuP
Description: Translation of PuuP
Type: translation
Pathway Components: puuAP_mRNA -> PuuP
Components:
Function Name Type
product PuuP protein
reactant puuAP_mRNA RNA
PuuP putrescine_Ext putrescine
Name: putrescine_Ext -> putrescine
Description: Transport of putrescine_Ext through a bacterial membrane, leading to the presence of putrescine inside the cell.
Type: transport
Pathway Components: putrescine_Ext - PuuP -> putrescine
Components:
Function Name Type
catalyzer PuuP protein
product putrescine simple_molecule
reactant putrescine_Ext simple_molecule
puuDRCBE_mRNA PuuD
Name: puuDRCBE_mRNA -> PuuD
Description: Translation of PuuD
Type: translation
Pathway Components: puuDRCBE_mRNA -> PuuD
Components:
Function Name Type
product PuuD protein
reactant puuDRCBE_mRNA RNA
PuuD γ-glu-GABA L-glutamate + GABA
Name: γ-glu-GABA -> L-glutamate + GABA
Description: Reaction transforming γ-glu-GABA into L-glutamate, GABA
Type: state transition
Pathway Components: γ-glu-GABA - PuuD -> L-glutamate + GABA
Components:
Function Name Type
reactant γ-glu-GABA simple_molecule
product GABA simple_molecule
product L-glutamate simple_molecule
catalyzer PuuD protein
puuDRCBE_mRNA PuuR
Name: puuDRCBE_mRNA -> PuuR
Description: Translation of PuuR
Type: translation
Pathway Components: puuDRCBE_mRNA -> PuuR
Components:
Function Name Type
product PuuR protein
reactant puuDRCBE_mRNA RNA
puuDRCBE_mRNA PuuC
Name: puuDRCBE_mRNA -> PuuC
Description: Translation of PuuC
Type: translation
Pathway Components: puuDRCBE_mRNA -> PuuC
Components:
Function Name Type
product PuuC protein
reactant puuDRCBE_mRNA RNA
PuuC ABAL GABA
Name: ABAL -> GABA
Description: Reaction transforming ABAL into GABA
Type: state transition
Pathway Components: ABAL - PuuC -> GABA
Components:
Function Name Type
reactant ABAL simple_molecule
product GABA simple_molecule
catalyzer PuuC protein
PuuC succ-S-ald succinate
Name: succ-S-ald -> succinate
Description: Reaction transforming succ-S-ald into succinate
Type: state transition
Pathway Components: succ-S-ald - PuuC -> succinate
Components:
Function Name Type
catalyzer PuuC protein
reactant succ-S-ald simple_molecule
product succinate simple_molecule
PuuC 3-hydroxypropanal hydracrylic acid
Name: 3-hydroxypropanal -> hydracrylic acid
Description: Reaction transforming 3-hydroxypropanal into hydracrylic acid
Type: state transition
Pathway Components: 3-hydroxypropanal - PuuC -> hydracrylic acid
Components:
Function Name Type
reactant 3-hydroxypropanal simple_molecule
catalyzer PuuC protein
product hydracrylic acid simple_molecule
PuuC 4-(γ-glutamylamino)butanal γ-glu-GABA
Name: 4-(γ-glutamylamino)butanal -> γ-glu-GABA
Description: Reaction transforming 4-(γ-glutamylamino)butanal into γ-glu-GABA
Type: state transition
Pathway Components: 4-(γ-glutamylamino)butanal - PuuC -> γ-glu-GABA
Components:
Function Name Type
product γ-glu-GABA simple_molecule
reactant 4-(γ-glutamylamino)butanal simple_molecule
catalyzer PuuC protein
puuDRCBE_mRNA PuuB
Name: puuDRCBE_mRNA -> PuuB
Description: Translation of PuuB
Type: translation
Pathway Components: puuDRCBE_mRNA -> PuuB
Components:
Function Name Type
product PuuB protein
reactant puuDRCBE_mRNA RNA
PuuB γ-Glu-Put + oxygen Products
Name: γ-Glu-Put + oxygen -> 4-(γ-glutamylamino)butanal + perhydrol + ammonium
Description: Reaction transforming γ-Glu-Put, oxygen into 4-(γ-glutamylamino)butanal, perhydrol , ammonium
Type: state transition
Pathway Components: γ-Glu-Put + oxygen - PuuB -> 4-(γ-glutamylamino)butanal + perhydrol + ammonium
Components:
Function Name Type
reactant γ-Glu-Put simple_molecule
product 4-(γ-glutamylamino)butanal simple_molecule
catalyzer PuuB protein
product ammonium simple_molecule
reactant oxygen simple_molecule
product perhydrol simple_molecule
puuDRCBE_mRNA PuuE
Name: puuDRCBE_mRNA -> PuuE
Description: Translation of PuuE
Type: translation
Pathway Components: puuDRCBE_mRNA -> PuuE
Components:
Function Name Type
product PuuE protein
reactant puuDRCBE_mRNA RNA
PuuE ketoglutarate + GABA L-glutamate + succ-S-ald
Name: ketoglutarate + GABA -> L-glutamate + succ-S-ald
Description: Reaction transforming ketoglutarate, GABA into L-glutamate, succ-S-ald
Type: state transition
Pathway Components: ketoglutarate + GABA - PuuE -> L-glutamate + succ-S-ald
Components:
Function Name Type
reactant GABA simple_molecule
product L-glutamate simple_molecule
catalyzer PuuE protein
reactant ketoglutarate simple_molecule
product succ-S-ald simple_molecule
putrescine ABAL
Name: putrescine -> ABAL
Description: Transformation of putrescine into ABAL by one or more reactions not shown.
Type: complementary pathway reaction
Pathway Components: putrescine / ABAL
Components:
Function Name Type
product ABAL simple_molecule
reactant putrescine simple_molecule
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