RegulonDB RegulonDB

PuuR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
glutamyl-L-putrescine ketoglutarate 4-glutamylamino-butanal 4-glutamylamino-butanoate GABA L-glutamate PuuA PuuB PuuC PuuD PuuE PuuP PuuR ammonium putrescine putrescine ext puuAP puuDRCBE puuAP mRNA puuDRCBE mRNA succ-S-ald L-glutamate L-glutamate


Gensor Unit       
Name: PuuR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:0006974 - cellular response to DNA damage stimulus
GO:0009450 - gamma-aminobutyric acid catabolic process
GO:0006542 - glutamine biosynthetic process
GO:0055114 - oxidation-reduction process
GO:0006598 - polyamine catabolic process
GO:0009447 - putrescine catabolic process
Read more >
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
molecular_function GO:0003867 - 4-aminobutyrate transaminase activity
GO:0003677 - DNA binding
GO:0004030 - aldehyde dehydrogenase [NAD(P)+] activity
GO:0003824 - catalytic activity
GO:0033969 - gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GO:0034024 - glutamate-putrescine ligase activity
GO:0016787 - hydrolase activity
Read more >
Components: Show/Hide Components Table (26 more...)
Function Name Type
simple_molecule γ-Glu-Put simple_molecule
simple_molecule γ-glu-GABA simple_molecule
simple_molecule 3-hydroxypropanal simple_molecule
simple_molecule 4-(γ-glutamylamino)butanal simple_molecule
simple_molecule GABA simple_molecule
simple_molecule L-glutamate simple_molecule
protein PuuA protein
protein PuuB protein
protein PuuC protein
protein PuuD protein
protein PuuE protein
protein PuuP protein
protein PuuR protein
simple_molecule ammonium simple_molecule
simple_molecule hydracrylic acid simple_molecule
simple_molecule ketoglutarate simple_molecule
simple_molecule oxygen simple_molecule
simple_molecule perhydrol simple_molecule
simple_molecule phosphate simple_molecule
simple_molecule putrescine simple_molecule
simple_molecule putrescine_Ext simple_molecule
gene puuAP gene
RNA puuAP_mRNA RNA
gene puuDRCBE gene
RNA puuDRCBE_mRNA RNA
simple_molecule succ-S-ald simple_molecule


Reactions       
Showing 16 reactions
PuuR puuAP puuAP_mRNA
Name: puuAP -> puuAP_mRNA
Description: Transcription of transcription unit puuAP. Reaction inhibition by PuuR.
Type: transcription
Pathway Components: puuAP - PuuR -> puuAP_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor PuuR protein nd nd
reactant puuAP gene nd nd
product puuAP_mRNA RNA nd nd
PuuR puuDRCBE puuDRCBE_mRNA
Name: puuDRCBE -> puuDRCBE_mRNA
Description: Transcription of transcription unit puuDRCBE. Reaction inhibition by PuuR.
Type: transcription
Pathway Components: puuDRCBE - PuuR -> puuDRCBE_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor PuuR protein nd nd
reactant puuDRCBE gene nd nd
product puuDRCBE_mRNA RNA nd nd
puuAP_mRNA PuuA
Name: puuAP_mRNA -> PuuA
Description: Translation of PuuA
Type: translation
Pathway Components: puuAP_mRNA -> PuuA
Components:
Function Name Type Evidence Reference(s)
product PuuA protein nd nd
reactant puuAP_mRNA RNA nd nd
PuuA L-glutamate + putrescine γ-Glu-Put + phosphate
Name: L-glutamate + putrescine -> γ-Glu-Put + phosphate
Description: Reaction transforming L-glutamate, putrescine into γ-Glu-Put, phosphate
Type: state transition
Pathway Components: L-glutamate + putrescine - PuuA -> γ-Glu-Put + phosphate
Components:
Function Name Type Evidence Reference(s)
product γ-Glu-Put simple_molecule nd nd
reactant L-glutamate simple_molecule nd nd
catalyzer PuuA protein nd nd
product phosphate simple_molecule nd nd
reactant putrescine simple_molecule nd nd
puuAP_mRNA PuuP
Name: puuAP_mRNA -> PuuP
Description: Translation of PuuP
Type: translation
Pathway Components: puuAP_mRNA -> PuuP
Components:
Function Name Type Evidence Reference(s)
product PuuP protein nd nd
reactant puuAP_mRNA RNA nd nd
PuuP putrescine_Ext putrescine
Name: putrescine_Ext -> putrescine
Description: Transport of putrescine_Ext through a bacterial membrane, leading to the presence of putrescine inside the cell.
Type: transport
Pathway Components: putrescine_Ext - PuuP -> putrescine
Components:
Function Name Type Evidence Reference(s)
catalyzer PuuP protein nd nd
product putrescine simple_molecule nd nd
reactant putrescine_Ext simple_molecule nd nd
puuDRCBE_mRNA PuuD
Name: puuDRCBE_mRNA -> PuuD
Description: Translation of PuuD
Type: translation
Pathway Components: puuDRCBE_mRNA -> PuuD
Components:
Function Name Type Evidence Reference(s)
product PuuD protein nd nd
reactant puuDRCBE_mRNA RNA nd nd
PuuD γ-glu-GABA L-glutamate + GABA
Name: γ-glu-GABA -> L-glutamate + GABA
Description: Reaction transforming γ-glu-GABA into L-glutamate, GABA
Type: state transition
Pathway Components: γ-glu-GABA - PuuD -> L-glutamate + GABA
Components:
Function Name Type Evidence Reference(s)
reactant γ-glu-GABA simple_molecule nd nd
product GABA simple_molecule nd nd
product L-glutamate simple_molecule nd nd
catalyzer PuuD protein nd nd
puuDRCBE_mRNA PuuR
Name: puuDRCBE_mRNA -> PuuR
Description: Translation of PuuR
Type: translation
Pathway Components: puuDRCBE_mRNA -> PuuR
Components:
Function Name Type Evidence Reference(s)
product PuuR protein nd nd
reactant puuDRCBE_mRNA RNA nd nd
puuDRCBE_mRNA PuuC
Name: puuDRCBE_mRNA -> PuuC
Description: Translation of PuuC
Type: translation
Pathway Components: puuDRCBE_mRNA -> PuuC
Components:
Function Name Type Evidence Reference(s)
product PuuC protein nd nd
reactant puuDRCBE_mRNA RNA nd nd
PuuC 3-hydroxypropanal hydracrylic acid
Name: 3-hydroxypropanal -> hydracrylic acid
Description: Reaction transforming 3-hydroxypropanal into hydracrylic acid
Type: state transition
Pathway Components: 3-hydroxypropanal - PuuC -> hydracrylic acid
Components:
Function Name Type Evidence Reference(s)
reactant 3-hydroxypropanal simple_molecule nd nd
catalyzer PuuC protein nd nd
product hydracrylic acid simple_molecule nd nd
PuuC 4-(γ-glutamylamino)butanal γ-glu-GABA
Name: 4-(γ-glutamylamino)butanal -> γ-glu-GABA
Description: Reaction transforming 4-(γ-glutamylamino)butanal into γ-glu-GABA
Type: state transition
Pathway Components: 4-(γ-glutamylamino)butanal - PuuC -> γ-glu-GABA
Components:
Function Name Type Evidence Reference(s)
product γ-glu-GABA simple_molecule nd nd
reactant 4-(γ-glutamylamino)butanal simple_molecule nd nd
catalyzer PuuC protein nd nd
puuDRCBE_mRNA PuuB
Name: puuDRCBE_mRNA -> PuuB
Description: Translation of PuuB
Type: translation
Pathway Components: puuDRCBE_mRNA -> PuuB
Components:
Function Name Type Evidence Reference(s)
product PuuB protein nd nd
reactant puuDRCBE_mRNA RNA nd nd
PuuB γ-Glu-Put + oxygen Products
Name: γ-Glu-Put + oxygen -> 4-(γ-glutamylamino)butanal + perhydrol + ammonium
Description: Reaction transforming γ-Glu-Put, oxygen into 4-(γ-glutamylamino)butanal, perhydrol , ammonium
Type: state transition
Pathway Components: γ-Glu-Put + oxygen - PuuB -> 4-(γ-glutamylamino)butanal + perhydrol + ammonium
Components:
Function Name Type Evidence Reference(s)
reactant γ-Glu-Put simple_molecule nd nd
product 4-(γ-glutamylamino)butanal simple_molecule nd nd
catalyzer PuuB protein nd nd
product ammonium simple_molecule nd nd
reactant oxygen simple_molecule nd nd
product perhydrol simple_molecule nd nd
puuDRCBE_mRNA PuuE
Name: puuDRCBE_mRNA -> PuuE
Description: Translation of PuuE
Type: translation
Pathway Components: puuDRCBE_mRNA -> PuuE
Components:
Function Name Type Evidence Reference(s)
product PuuE protein nd nd
reactant puuDRCBE_mRNA RNA nd nd
PuuE ketoglutarate + GABA L-glutamate + succ-S-ald
Name: ketoglutarate + GABA -> L-glutamate + succ-S-ald
Description: Reaction transforming ketoglutarate, GABA into L-glutamate, succ-S-ald
Type: state transition
Pathway Components: ketoglutarate + GABA - PuuE -> L-glutamate + succ-S-ald
Components:
Function Name Type Evidence Reference(s)
reactant GABA simple_molecule nd nd
product L-glutamate simple_molecule nd nd
catalyzer PuuE protein nd nd
reactant ketoglutarate simple_molecule nd nd
product succ-S-ald simple_molecule nd nd



RegulonDB