RegulonDB RegulonDB

PrpR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
methylisocitrate (2S,3S)-2-methylcitrate 2-methylcitrate PrpB PrpC PrpD PrpE PrpR ac-CoA 2-methylaconitate cit CoA PP oxalacetate propanoate propanoyl-CoA prpBCDE prpBCDE_mRNA prpR prpR_mRNA pyruvate succinate PrpR 2-methylcitrate


Gensor Unit       
Name: PrpR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0045892 - negative regulation of transcription, DNA-templated
GO:0047547 - 2-methylcitrate dehydratase activity
GO:0050440 - 2-methylcitrate synthase activity
GO:0044262 - cellular carbohydrate metabolic process
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0003824 - catalytic activity
GO:0006099 - tricarboxylic acid cycle
GO:0051537 - 2 iron, 2 sulfur cluster binding
GO:0005737 - cytoplasm
GO:0016829 - lyase activity
GO:0045893 - positive regulation of transcription, DNA-templated
Read more >
Components:
Function Name Type
RNA prpR_mRNA RNA


Reactions       
Showing 8 reactions
prpBCDE prpBCDE_mRNA
Name: prpBCDE -> prpBCDE_mRNA
Description: Transcription of transcription unit prpBCDE; reaction inhibition by Cra.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant prpBCDE gene nd nd
product prpBCDE_mRNA RNA nd nd
prpR prpR_mRNA
Name: prpR -> prpR_mRNA
Description: Transcription of transcription unit prpR; reaction inhibition by AscG.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product prpR_mRNA RNA nd nd
reactant prpR gene nd nd
(2S,3S)-2-methylcitrate + PrpR PrpR-(2S,3S)-2-methylcitrate
Name: (2S,3S)-2-methylcitrate + PrpR -> PrpR-(2S,3S)-2-methylcitrate
Description: Reaction transforming (2S,3S)-2-methylcitrate, PrpR into PrpR-(2S,3S)-2-methylcitrate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant (2S,3S)-2-methylcitrate simple molecule nd nd
reactant PrpR protein nd nd
product PrpR-(2S,3S)-2-methylcitrate complex nd nd
prpR_mRNA PrpR
Name: prpR_mRNA -> PrpR
Description: Translation of PrpR
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant prpR_mRNA RNA nd nd
product PrpR protein nd nd
prpBCDE_mRNA PrpB
Name: prpBCDE_mRNA -> PrpB
Description: Translation of PrpB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant prpBCDE_mRNA RNA nd nd
product PrpB protein nd nd
prpBCDE_mRNA PrpC
Name: prpBCDE_mRNA -> PrpC
Description: Translation of PrpC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PrpC protein nd nd
reactant prpBCDE_mRNA RNA nd nd
prpBCDE_mRNA PrpD
Name: prpBCDE_mRNA -> PrpD
Description: Translation of PrpD
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant prpBCDE_mRNA RNA nd nd
product PrpD protein nd nd
prpBCDE_mRNA PrpE
Name: prpBCDE_mRNA -> PrpE
Description: Translation of PrpE
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PrpE protein nd nd
reactant prpBCDE_mRNA RNA nd nd



RegulonDB