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PaaX Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
2,3-dehydroadipyl-CoA 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA oxepin-CoA homoprotocatechuate 3,4-dihydroxyphenylacetyl-CoA 3-hydroxyadipyl-CoA 3-oxo-5,6-dehydrosuberyl-CoA 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde 3-oxoadipyl-CoA PaaA PaaB PaaC PaaD PaaE PaaF PaaG PaaH PaaI PaaJ PaaK PaaX PaaZ 3-OH-acyl-CoA trans-2,3-dehydroacyl-CoA ac-CoA CoA PP oxygen paaABCDEFGHIJK paaABCDEFGHIJK_mRNA paaZ paaZ_mRNA phenylacetate phenylacetyl-CoA suc-coa PaaE PaaA PaaC PaaB CoA


Gensor Unit       
Name: PaaX
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0050662 - coenzyme binding
GO:0003824 - catalytic activity
GO:0006631 - fatty acid metabolic process
GO:0016491 - oxidoreductase activity
GO:0051537 - 2 iron, 2 sulfur cluster binding
GO:0004300 - enoyl-CoA hydratase activity
GO:0016829 - lyase activity
GO:0047475 - phenylacetate-CoA ligase activity
GO:0019619 - 3,4-dihydroxybenzoate catabolic process
GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016790 - thiolester hydrolase activity
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Components:
Function Name Type
simple molecule suc-coa simple molecule


Reactions       
Showing 27 reactions
paaABCDEFGHIJK paaABCDEFGHIJK_mRNA
Name: paaABCDEFGHIJK -> paaABCDEFGHIJK_mRNA
Description: Transcription of transcription unit paaABCDEFGHIJK; reaction inhibition by PaaX.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant paaABCDEFGHIJK gene nd nd
product paaABCDEFGHIJK_mRNA RNA nd nd
paaZ paaZ_mRNA
Name: paaZ -> paaZ_mRNA
Description: Transcription of transcription unit paaZ; reaction inhibition by PaaX.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product paaZ_mRNA RNA nd nd
reactant paaZ gene nd nd
paaABCDEFGHIJK_mRNA PaaI
Name: paaABCDEFGHIJK_mRNA -> PaaI
Description: Translation of PaaI
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PaaI protein nd nd
reactant paaABCDEFGHIJK_mRNA RNA nd nd
3,4-dihydroxyphenylacetyl-CoA homoprotocatechuate + CoA
Name: 3,4-dihydroxyphenylacetyl-CoA -> homoprotocatechuate + CoA
Description: Reaction transforming 3,4-dihydroxyphenylacetyl-CoA into homoprotocatechuate, CoA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant 3,4-dihydroxyphenylacetyl-CoA simple molecule nd nd
product CoA simple molecule nd nd
product homoprotocatechuate simple molecule nd nd
paaABCDEFGHIJK_mRNA PaaC
Name: paaABCDEFGHIJK_mRNA -> PaaC
Description: Translation of PaaC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PaaC protein nd nd
reactant paaABCDEFGHIJK_mRNA RNA nd nd
PaaE + PaaA + PaaC + PaaB PaaE-PaaA-PaaC-PaaB
Name: PaaE + PaaA + PaaC + PaaB -> PaaE-PaaA-PaaC-PaaB
Description: Reaction transforming PaaE, PaaA, PaaC, PaaB into PaaE-PaaA-PaaC-PaaB
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant PaaB protein nd nd
reactant PaaC protein nd nd
reactant PaaE protein nd nd
reactant PaaA protein nd nd
product PaaE-PaaA-PaaC-PaaB complex nd nd
phenylacetyl-CoA + oxygen 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA
Name: phenylacetyl-CoA + oxygen -> 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA
Description: Reaction transforming phenylacetyl-CoA, oxygen into 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA simple molecule nd nd
reactant phenylacetyl-CoA simple molecule nd nd
reactant oxygen simple molecule nd nd
paaABCDEFGHIJK_mRNA PaaH
Name: paaABCDEFGHIJK_mRNA -> PaaH
Description: Translation of PaaH
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PaaH protein nd nd
reactant paaABCDEFGHIJK_mRNA RNA nd nd
3-hydroxyadipyl-CoA 3-oxoadipyl-CoA
Name: 3-hydroxyadipyl-CoA -> 3-oxoadipyl-CoA
Description: Reaction transforming 3-hydroxyadipyl-CoA into 3-oxoadipyl-CoA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product 3-oxoadipyl-CoA simple molecule nd nd
reactant 3-hydroxyadipyl-CoA simple molecule nd nd
paaZ_mRNA PaaZ
Name: paaZ_mRNA -> PaaZ
Description: Translation of PaaZ
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant paaZ_mRNA RNA nd nd
product PaaZ protein nd nd
oxepin-CoA 3-oxo-5,6-dehydrosuberyl-CoA
Name: oxepin-CoA -> 3-oxo-5,6-dehydrosuberyl-CoA
Description: Reaction transforming oxepin-CoA into 3-oxo-5,6-dehydrosuberyl-CoA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant oxepin-CoA simple molecule nd nd
product 3-oxo-5,6-dehydrosuberyl-CoA simple molecule nd nd
oxepin-CoA 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde
Name: oxepin-CoA -> 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde
Description: Reaction transforming oxepin-CoA into 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant oxepin-CoA simple molecule nd nd
product 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde simple molecule nd nd
3-oxo-5,6-dehydrosuberyl-CoA semialdehyde 3-oxo-5,6-dehydrosuberyl-CoA
Name: 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde -> 3-oxo-5,6-dehydrosuberyl-CoA
Description: Reaction transforming 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde into 3-oxo-5,6-dehydrosuberyl-CoA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde simple molecule nd nd
product 3-oxo-5,6-dehydrosuberyl-CoA simple molecule nd nd
3-OH-acyl-CoA trans-2,3-dehydroacyl-CoA
Name: 3-OH-acyl-CoA -> trans-2,3-dehydroacyl-CoA
Description: Reaction transforming 3-OH-acyl-CoA into trans-2,3-dehydroacyl-CoA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product trans-2,3-dehydroacyl-CoA simple molecule nd nd
reactant 3-OH-acyl-CoA simple molecule nd nd
paaABCDEFGHIJK_mRNA PaaA
Name: paaABCDEFGHIJK_mRNA -> PaaA
Description: Translation of PaaA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PaaA protein nd nd
reactant paaABCDEFGHIJK_mRNA RNA nd nd
paaABCDEFGHIJK_mRNA PaaG
Name: paaABCDEFGHIJK_mRNA -> PaaG
Description: Translation of PaaG
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant paaABCDEFGHIJK_mRNA RNA nd nd
product PaaG protein nd nd
2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA oxepin-CoA
Name: 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA -> oxepin-CoA
Description: Reaction transforming 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA into oxepin-CoA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product oxepin-CoA simple molecule nd nd
reactant 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA simple molecule nd nd
paaABCDEFGHIJK_mRNA PaaF
Name: paaABCDEFGHIJK_mRNA -> PaaF
Description: Translation of PaaF
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant paaABCDEFGHIJK_mRNA RNA nd nd
product PaaF protein nd nd
3-hydroxyadipyl-CoA 2,3-dehydroadipyl-CoA
Name: 3-hydroxyadipyl-CoA -> 2,3-dehydroadipyl-CoA
Description: Reaction transforming 3-hydroxyadipyl-CoA into 2,3-dehydroadipyl-CoA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product 2,3-dehydroadipyl-CoA simple molecule nd nd
reactant 3-hydroxyadipyl-CoA simple molecule nd nd
paaABCDEFGHIJK_mRNA PaaD
Name: paaABCDEFGHIJK_mRNA -> PaaD
Description: Translation of PaaD
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PaaD protein nd nd
reactant paaABCDEFGHIJK_mRNA RNA nd nd
paaABCDEFGHIJK_mRNA PaaJ
Name: paaABCDEFGHIJK_mRNA -> PaaJ
Description: Translation of PaaJ
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PaaJ protein nd nd
reactant paaABCDEFGHIJK_mRNA RNA nd nd
2,3-dehydroadipyl-CoA + ac-CoA 3-oxo-5,6-dehydrosuberyl-CoA + CoA
Name: 2,3-dehydroadipyl-CoA + ac-CoA -> 3-oxo-5,6-dehydrosuberyl-CoA + CoA
Description: Reaction transforming 2,3-dehydroadipyl-CoA, ac-CoA into 3-oxo-5,6-dehydrosuberyl-CoA, CoA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product CoA simple molecule nd nd
product 3-oxo-5,6-dehydrosuberyl-CoA simple molecule nd nd
reactant ac-CoA simple molecule nd nd
reactant 2,3-dehydroadipyl-CoA simple molecule nd nd
suc-coa + ac-CoA 3-oxoadipyl-CoA + CoA
Name: suc-coa + ac-CoA -> 3-oxoadipyl-CoA + CoA
Description: Reaction transforming suc-coa, ac-CoA into 3-oxoadipyl-CoA, CoA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product CoA simple molecule nd nd
reactant suc-coa simple molecule nd nd
product 3-oxoadipyl-CoA simple molecule nd nd
reactant ac-CoA simple molecule nd nd
paaABCDEFGHIJK_mRNA PaaK
Name: paaABCDEFGHIJK_mRNA -> PaaK
Description: Translation of PaaK
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant paaABCDEFGHIJK_mRNA RNA nd nd
product PaaK protein nd nd
CoA + phenylacetate phenylacetyl-CoA + PP
Name: CoA + phenylacetate -> phenylacetyl-CoA + PP
Description: Reaction transforming CoA, phenylacetate into phenylacetyl-CoA, PP
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product PP simple molecule nd nd
reactant CoA simple molecule nd nd
product phenylacetyl-CoA simple molecule nd nd
reactant phenylacetate simple molecule nd nd
paaABCDEFGHIJK_mRNA PaaE
Name: paaABCDEFGHIJK_mRNA -> PaaE
Description: Translation of PaaE
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PaaE protein nd nd
reactant paaABCDEFGHIJK_mRNA RNA nd nd
paaABCDEFGHIJK_mRNA PaaB
Name: paaABCDEFGHIJK_mRNA -> PaaB
Description: Translation of PaaB
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PaaB protein nd nd
reactant paaABCDEFGHIJK_mRNA RNA nd nd



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