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NemR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
GloA N-EM ethylsuccinimide NemA NemR S-lactoyl-glutathione GSH oxopropanal nemRA nemRA-gloA nemRA-gloA_mRNA nemRA_mRNA


Gensor Unit       
Name: NemR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:0046256 - 2,4,6-trinitrotoluene catabolic process
GO:0019243 - methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
GO:0045892 - negative regulation of transcription, DNA-templated
GO:0018937 - nitroglycerin metabolic process
GO:0009636 - response to toxic substance
GO:0006805 - xenobiotic metabolic process
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cellular_component GO:0005829 - cytosol
molecular_function GO:0003700 - DNA binding transcription factor activity
GO:0010181 - FMN binding
GO:0008748 - N-ethylmaleimide reductase activity
GO:0034567 - chromate reductase activity
GO:0004462 - lactoylglutathione lyase activity
GO:0016151 - nickel cation binding
GO:0046857 - oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor
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Components: Show/Hide Components Table (12 more...)
Function Name Type
protein GloA protein
simple_molecule N-EM simple_molecule
protein NemA protein
protein NemR protein
simple_molecule ethylsuccinimide simple_molecule
simple_molecule glutathione simple_molecule
simple_molecule lactoylglutathione simple_molecule
gene nemRA gene
gene nemRA-gloA gene
RNA nemRA-gloA_mRNA RNA
RNA nemRA_mRNA RNA
simple_molecule oxopropanal simple_molecule


Reactions       
Showing 9 reactions
NemR nemRA nemRA_mRNA
Name: nemRA -> nemRA_mRNA
Description: Transcription of transcription unit nemRA. Reaction inhibition by NemR.
Type: transcription
Pathway Components: nemRA - NemR -> nemRA_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor NemR protein nd nd
reactant nemRA gene nd nd
product nemRA_mRNA RNA nd nd
NemR nemRA-gloA nemRA-gloA_mRNA
Name: nemRA-gloA -> nemRA-gloA_mRNA
Description: Transcription of transcription unit nemRA-gloA. Reaction inhibition by NemR.
Type: transcription
Pathway Components: nemRA-gloA - NemR -> nemRA-gloA_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor NemR protein nd nd
reactant nemRA-gloA gene nd nd
product nemRA-gloA_mRNA RNA nd nd
nemRA_mRNA NemR
Name: nemRA_mRNA -> NemR
Description: Translation of NemR
Type: translation
Pathway Components: nemRA_mRNA -> NemR
Components:
Function Name Type Evidence Reference(s)
product NemR protein nd nd
reactant nemRA_mRNA RNA nd nd
nemRA_mRNA NemA
Name: nemRA_mRNA -> NemA
Description: Translation of NemA
Type: translation
Pathway Components: nemRA_mRNA -> NemA
Components:
Function Name Type Evidence Reference(s)
product NemA protein nd nd
reactant nemRA_mRNA RNA nd nd
NemA N-EM ethylsuccinimide
Name: N-EM -> ethylsuccinimide
Description: Reaction transforming N-EM into ethylsuccinimide
Type: state transition
Pathway Components: N-EM - NemA -> ethylsuccinimide
Components:
Function Name Type Evidence Reference(s)
reactant N-EM simple_molecule nd nd
catalyzer NemA protein nd nd
product ethylsuccinimide simple_molecule nd nd
nemRA-gloA_mRNA NemR
Name: nemRA-gloA_mRNA -> NemR
Description: Translation of NemR
Type: translation
Pathway Components: nemRA-gloA_mRNA -> NemR
Components:
Function Name Type Evidence Reference(s)
product NemR protein nd nd
reactant nemRA-gloA_mRNA RNA nd nd
nemRA-gloA_mRNA NemA
Name: nemRA-gloA_mRNA -> NemA
Description: Translation of NemA
Type: translation
Pathway Components: nemRA-gloA_mRNA -> NemA
Components:
Function Name Type Evidence Reference(s)
product NemA protein nd nd
reactant nemRA-gloA_mRNA RNA nd nd
nemRA-gloA_mRNA GloA
Name: nemRA-gloA_mRNA -> GloA
Description: Translation of GloA
Type: translation
Pathway Components: nemRA-gloA_mRNA -> GloA
Components:
Function Name Type Evidence Reference(s)
product GloA protein nd nd
reactant nemRA-gloA_mRNA RNA nd nd
GloA oxopropanal + glutathione lactoylglutathione
Name: oxopropanal + glutathione -> lactoylglutathione
Description: Reaction transforming oxopropanal, glutathione into lactoylglutathione
Type: state transition
Pathway Components: oxopropanal + glutathione - GloA -> lactoylglutathione
Components:
Function Name Type Evidence Reference(s)
catalyzer GloA protein nd nd
reactant glutathione simple_molecule nd nd
product lactoylglutathione simple_molecule nd nd
reactant oxopropanal simple_molecule nd nd



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