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MurR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
D-lactate Crr MurP MurQ MurR N-acetyl-D-glucosamine-6-phosphate MurNAc-6-P MurNAc_Ext murQP murQP_mRNA murR murR_mRNA PEP_Ext pyruvate MurR MurNAc-6-P MurP Crr


Gensor Unit       
Name: MurR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0045892 - negative regulation of transcription, DNA-templated
GO:0016020 - membrane
GO:0009401 - phosphoenolpyruvate-dependent sugar phosphotransferase system
GO:0005887 - integral component of plasma membrane
GO:0016310 - phosphorylation
GO:0016829 - lyase activity
GO:0008982 - protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO:0043470 - regulation of carbohydrate catabolic process
GO:0009254 - peptidoglycan turnover
GO:0003677 - DNA binding
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Components:
Function Name Type
simple molecule pyruvate simple molecule


Reactions       
Showing 9 reactions
murQP murQP_mRNA
Name: murQP -> murQP_mRNA
Description: Transcription of transcription unit murQP; reaction inhibition by MurR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant murQP gene nd nd
product murQP_mRNA RNA nd nd
murR murR_mRNA
Name: murR -> murR_mRNA
Description: Transcription of transcription unit murR; reaction inhibition by MurR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product murR_mRNA RNA nd nd
reactant murR gene nd nd
MurR + MurNAc-6-P MurR-MurNAc-6-P
Name: MurR + MurNAc-6-P -> MurR-MurNAc-6-P
Description: Reaction transforming MurR, MurNAc-6-P into MurR-MurNAc-6-P
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product MurR-MurNAc-6-P complex nd nd
reactant MurR protein nd nd
reactant MurNAc-6-P simple molecule nd nd
murR_mRNA MurR
Name: murR_mRNA -> MurR
Description: Translation of MurR
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MurR protein nd nd
reactant murR_mRNA RNA nd nd
murQP_mRNA MurP
Name: murQP_mRNA -> MurP
Description: Translation of MurP
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant murQP_mRNA RNA nd nd
product MurP protein nd nd
MurP + Crr MurP-Crr
Name: MurP + Crr -> MurP-Crr
Description: Reaction transforming MurP, Crr into MurP-Crr
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant Crr protein nd nd
reactant MurP protein nd nd
product MurP-Crr complex nd nd
PEP_Ext + MurNAc_Ext MurNAc-6-P + pyruvate
Name: PEP_Ext + MurNAc_Ext -> MurNAc-6-P + pyruvate
Description: Transport of PEP_Ext, MurNAc_Ext through a bacterial membrane, leading to the presence of MurNAc-6-P, pyruvate inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant PEP_Ext simple molecule nd nd
product MurNAc-6-P simple molecule nd nd
product pyruvate simple molecule nd nd
reactant MurNAc_Ext simple molecule nd nd
murQP_mRNA MurQ
Name: murQP_mRNA -> MurQ
Description: Translation of MurQ
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MurQ protein nd nd
reactant murQP_mRNA RNA nd nd
MurNAc-6-P N-acetyl-D-glucosamine-6-phosphate + D-lactate
Name: MurNAc-6-P -> N-acetyl-D-glucosamine-6-phosphate + D-lactate
Description: Reaction transforming MurNAc-6-P into N-acetyl-D-glucosamine-6-phosphate, D-lactate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant MurNAc-6-P simple molecule nd nd
product N-acetyl-D-glucosamine-6-phosphate simple molecule nd nd
product D-lactate simple molecule nd nd



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