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NadR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
nicotinamide ribose nicotinamide ribose_Ext PRPP asp NadA NadB NadR PncB PnuC iminoaspartate NaMN DHAP PP fumarate perhydrol nadA-pnuC nadA-pnuC_mRNA nadB nadB_mRNA niacin oxygen phosphate pncB pncB_mRNA quinolinate succinate


Gensor Unit       
Name: NadR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0016491 - oxidoreductase activity
GO:0016020 - membrane
GO:0034257 - nicotinamide riboside transmembrane transporter activity
GO:0005887 - integral component of plasma membrane
GO:0005737 - cytoplasm
GO:0044318 - L-aspartate:fumarate oxidoreductase activity
GO:0019357 - nicotinate nucleotide biosynthetic process
GO:0016740 - transferase activity
GO:0034628 - 'de novo' NAD biosynthetic process from aspartate
GO:0008734 - L-aspartate oxidase activity
GO:0005886 - plasma membrane
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Components:
Function Name Type
simple molecule suc simple molecule


Reactions       
Showing 12 reactions
nadA-pnuC nadA-pnuC_mRNA
Name: nadA-pnuC -> nadA-pnuC_mRNA
Description: Transcription of transcription unit nadA-pnuC; reaction inhibition by NadR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product nadA-pnuC_mRNA RNA nd nd
reactant nadA-pnuC gene nd nd
nadB nadB_mRNA
Name: nadB -> nadB_mRNA
Description: Transcription of transcription unit nadB; reaction inhibition by NadR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant nadB gene nd nd
product nadB_mRNA RNA nd nd
pncB pncB_mRNA
Name: pncB -> pncB_mRNA
Description: Transcription of transcription unit pncB; reaction inhibition by NadR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product pncB_mRNA RNA nd nd
reactant pncB gene nd nd
nadA-pnuC_mRNA PnuC
Name: nadA-pnuC_mRNA -> PnuC
Description: Translation of PnuC
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant nadA-pnuC_mRNA RNA nd nd
product PnuC protein nd nd
nicotinamide ribose_Ext nicotinamide ribose
Name: nicotinamide ribose_Ext -> nicotinamide ribose
Description: Transport of nicotinamide ribose_Ext through a bacterial membrane, leading to the presence of nicotinamide ribose inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product nicotinamide ribose simple molecule nd nd
reactant nicotinamide ribose_Ext simple molecule nd nd
nadB_mRNA NadB
Name: nadB_mRNA -> NadB
Description: Translation of NadB
Type: translation
Components:
Function Name Type Evidence Reference(s)
product NadB protein nd nd
reactant nadB_mRNA RNA nd nd
asp + fumarate iminoaspartate + suc
Name: asp + fumarate -> iminoaspartate + suc
Description: Reaction transforming asp, fumarate into iminoaspartate, suc
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant fumarate simple molecule nd nd
product iminoaspartate simple molecule nd nd
reactant asp simple molecule nd nd
product suc simple molecule nd nd
oxygen + asp perhydrol + iminoaspartate
Name: oxygen + asp -> perhydrol + iminoaspartate
Description: Reaction transforming oxygen, asp into perhydrol, iminoaspartate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant asp simple molecule nd nd
product perhydrol simple molecule nd nd
product iminoaspartate simple molecule nd nd
reactant oxygen simple molecule nd nd
nadA-pnuC_mRNA NadA
Name: nadA-pnuC_mRNA -> NadA
Description: Translation of NadA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant nadA-pnuC_mRNA RNA nd nd
product NadA protein nd nd
iminoaspartate + DHAP quinolinate + phosphate
Name: iminoaspartate + DHAP -> quinolinate + phosphate
Description: Reaction transforming iminoaspartate, DHAP into quinolinate, phosphate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant iminoaspartate simple molecule nd nd
product quinolinate simple molecule nd nd
product phosphate simple molecule nd nd
reactant DHAP simple molecule nd nd
pncB_mRNA PncB
Name: pncB_mRNA -> PncB
Description: Translation of PncB
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PncB protein nd nd
reactant pncB_mRNA RNA nd nd
NaMN + PP niacin + PRPP
Name: NaMN + PP -> niacin + PRPP
Description: Reaction transforming NaMN, PP into niacin, PRPP
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product niacin simple molecule nd nd
product PRPP simple molecule nd nd
reactant NaMN simple molecule nd nd
reactant PP simple molecule nd nd



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