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Nac Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
2'-deoxyadenosine 2'-deoxyadenosine_Ext 2'-deoxycytidine 2'-deoxycytidine_Ext 2'-deoxyinosine 2'-deoxyinosine_Ext 2'-deoxyuridine 2'-deoxyuridine_Ext 2-hydroxyglutarate ketoglutarate 3-phospho-D-glycerate 3-p-OH-pyr ABAL GABA GABA_Ext AsnC CodA CodB GabD GabP GabT GdhA GltB GltD GltF L-glutamate L-glutamine MioC MnmG Nac NupC PatD SerA YdcS YdcT YdcU YdcV adenosine adenosine_Ext ammonia asnC asnC-mioC asnC-mioC-mnmG asnC-mioC-mnmG_mRNA asnC-mioC_mRNA asnC_mRNA codBA codBA_mRNA cytidine cytidine_Ext cytosine cytosine_Ext gabDTP gabDTP_mRNA gdhA gdhA_mRNA gltBDF gltBDF_mRNA inosine inosine_Ext isoguanine nac nac_mRNA nupC nupC_mRNA serA serA_mRNA succinate succ-S-ald thymidine thymidine_Ext uracil uridine uridine_Ext xanthine ydcSTUV-patD ydcSTUV-patD_mRNA GltB GltD


Gensor Unit       
Name: Nac
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0045892 - negative regulation of transcription, DNA-templated
GO:0043190 - ATP-binding cassette (ABC) transporter complex
GO:0008270 - zinc ion binding
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0003824 - catalytic activity
GO:0015209 - cytosine transmembrane transporter activity
GO:0015212 - cytidine transmembrane transporter activity
GO:0005622 - intracellular
GO:0004354 - glutamate dehydrogenase (NADP+) activity
GO:0008652 - cellular amino acid biosynthetic process
GO:0010181 - FMN binding
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Components:
Function Name Type
RNA ydcSTUV-patD_mRNA RNA


Reactions       
Showing 56 reactions
asnC asnC_mRNA
Name: asnC -> asnC_mRNA
Description: Transcription of transcription unit asnC; reaction inhibition by AsnC.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant asnC gene nd nd
product asnC_mRNA RNA nd nd
asnC-mioC asnC-mioC_mRNA
Name: asnC-mioC -> asnC-mioC_mRNA
Description: Transcription of transcription unit asnC-mioC; reaction inhibition by AsnC.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product asnC-mioC_mRNA RNA nd nd
reactant asnC-mioC gene nd nd
asnC-mioC-mnmG asnC-mioC-mnmG_mRNA
Name: asnC-mioC-mnmG -> asnC-mioC-mnmG_mRNA
Description: Transcription of transcription unit asnC-mioC-mnmG; reaction inhibition by AsnC.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product asnC-mioC-mnmG_mRNA RNA nd nd
reactant asnC-mioC-mnmG gene nd nd
codBA codBA_mRNA
Name: codBA -> codBA_mRNA
Description: Transcription of transcription unit codBA; reaction activation by Nac.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant codBA gene nd nd
product codBA_mRNA RNA nd nd
gabDTP gabDTP_mRNA
Name: gabDTP -> gabDTP_mRNA
Description: Transcription of transcription unit gabDTP; reaction activation by Nac.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant gabDTP gene nd nd
product gabDTP_mRNA RNA nd nd
gdhA gdhA_mRNA
Name: gdhA -> gdhA_mRNA
Description: Transcription of transcription unit gdhA; reaction activation by ArgP.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant gdhA gene nd nd
product gdhA_mRNA RNA nd nd
gltBDF gltBDF_mRNA
Name: gltBDF -> gltBDF_mRNA
Description: Transcription of transcription unit gltBDF; reaction activation by AdiY.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant gltBDF gene nd nd
product gltBDF_mRNA RNA nd nd
nac nac_mRNA
Name: nac -> nac_mRNA
Description: Transcription of transcription unit nac; reaction inhibition by Fur-Fe(II).
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant nac gene nd nd
product nac_mRNA RNA nd nd
nupC nupC_mRNA
Name: nupC -> nupC_mRNA
Description: Transcription of transcription unit nupC; reaction inhibition by CytR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product nupC_mRNA RNA nd nd
reactant nupC gene nd nd
serA serA_mRNA
Name: serA -> serA_mRNA
Description: Transcription of transcription unit serA; reaction inhibition by Nac.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant serA gene nd nd
product serA_mRNA RNA nd nd
ydcSTUV-patD ydcSTUV-patD_mRNA
Name: ydcSTUV-patD -> ydcSTUV-patD_mRNA
Description: Transcription of transcription unit ydcSTUV-patD; reaction activation by Nac.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant ydcSTUV-patD gene nd nd
product ydcSTUV-patD_mRNA RNA nd nd
ydcSTUV-patD_mRNA YdcU
Name: ydcSTUV-patD_mRNA -> YdcU
Description: Translation of YdcU
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant ydcSTUV-patD_mRNA RNA nd nd
product YdcU protein nd nd
codBA_mRNA CodB
Name: codBA_mRNA -> CodB
Description: Translation of CodB
Type: translation
Components:
Function Name Type Evidence Reference(s)
product CodB protein nd nd
reactant codBA_mRNA RNA nd nd
cytosine_Ext cytosine
Name: cytosine_Ext -> cytosine
Description: Transport of cytosine_Ext through a bacterial membrane, leading to the presence of cytosine inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant cytosine_Ext simple molecule nd nd
product cytosine simple molecule nd nd
gabDTP_mRNA GabD
Name: gabDTP_mRNA -> GabD
Description: Translation of GabD
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GabD protein nd nd
reactant gabDTP_mRNA RNA nd nd
succ-S-ald suc
Name: succ-S-ald -> suc
Description: Reaction transforming succ-S-ald into suc
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant succ-S-ald simple molecule nd nd
product suc simple molecule nd nd
gabDTP_mRNA GabP
Name: gabDTP_mRNA -> GabP
Description: Translation of GabP
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GabP protein nd nd
reactant gabDTP_mRNA RNA nd nd
GABA_Ext GABA
Name: GABA_Ext -> GABA
Description: Transport of GABA_Ext through a bacterial membrane, leading to the presence of GABA inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant GABA_Ext simple molecule nd nd
product GABA simple molecule nd nd
asnC-mioC-mnmG_mRNA MioC
Name: asnC-mioC-mnmG_mRNA -> MioC
Description: Translation of MioC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MioC protein nd nd
reactant asnC-mioC-mnmG_mRNA RNA nd nd
codBA_mRNA CodA
Name: codBA_mRNA -> CodA
Description: Translation of CodA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant codBA_mRNA RNA nd nd
product CodA protein nd nd
isoguanine xanthine + ammonia
Name: isoguanine -> xanthine + ammonia
Description: Reaction transforming isoguanine into xanthine, ammonia
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant isoguanine simple molecule nd nd
product xanthine simple molecule nd nd
product ammonia simple molecule nd nd
cytosine ammonia + uracil
Name: cytosine -> ammonia + uracil
Description: Reaction transforming cytosine into ammonia, uracil
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product ammonia simple molecule nd nd
product uracil simple molecule nd nd
reactant cytosine simple molecule nd nd
gltBDF_mRNA GltD
Name: gltBDF_mRNA -> GltD
Description: Translation of GltD
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GltD protein nd nd
reactant gltBDF_mRNA RNA nd nd
GltB + GltD GltB-GltD
Name: GltB + GltD -> GltB-GltD
Description: Reaction transforming GltB, GltD into GltB-GltD
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant GltB protein nd nd
product GltB-GltD complex nd nd
reactant GltD protein nd nd
L-glutamate L-glutamine + ketoglutarate
Name: L-glutamate -> L-glutamine + ketoglutarate
Description: Reaction transforming L-glutamate into L-glutamine, ketoglutarate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product L-glutamine simple molecule nd nd
product ketoglutarate simple molecule nd nd
reactant L-glutamate simple molecule nd nd
L-glutamine L-glutamate + ammonia
Name: L-glutamine -> L-glutamate + ammonia
Description: Reaction transforming L-glutamine into L-glutamate, ammonia
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product L-glutamate simple molecule nd nd
reactant L-glutamine simple molecule nd nd
product ammonia simple molecule nd nd
L-glutamate ketoglutarate + ammonia
Name: L-glutamate -> ketoglutarate + ammonia
Description: Reaction transforming L-glutamate into ketoglutarate, ammonia
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant L-glutamate simple molecule nd nd
product ketoglutarate simple molecule nd nd
product ammonia simple molecule nd nd
ydcSTUV-patD_mRNA YdcT
Name: ydcSTUV-patD_mRNA -> YdcT
Description: Translation of YdcT
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant ydcSTUV-patD_mRNA RNA nd nd
product YdcT protein nd nd
gltBDF_mRNA GltF
Name: gltBDF_mRNA -> GltF
Description: Translation of GltF
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GltF protein nd nd
reactant gltBDF_mRNA RNA nd nd
asnC-mioC-mnmG_mRNA MnmG
Name: asnC-mioC-mnmG_mRNA -> MnmG
Description: Translation of MnmG
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MnmG protein nd nd
reactant asnC-mioC-mnmG_mRNA RNA nd nd
nac_mRNA Nac
Name: nac_mRNA -> Nac
Description: Translation of Nac
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant nac_mRNA RNA nd nd
product Nac protein nd nd
ydcSTUV-patD_mRNA PatD
Name: ydcSTUV-patD_mRNA -> PatD
Description: Translation of PatD
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PatD protein nd nd
reactant ydcSTUV-patD_mRNA RNA nd nd
ABAL GABA
Name: ABAL -> GABA
Description: Reaction transforming ABAL into GABA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant ABAL simple molecule nd nd
product GABA simple molecule nd nd
ydcSTUV-patD_mRNA YdcV
Name: ydcSTUV-patD_mRNA -> YdcV
Description: Translation of YdcV
Type: translation
Components:
Function Name Type Evidence Reference(s)
product YdcV protein nd nd
reactant ydcSTUV-patD_mRNA RNA nd nd
serA_mRNA SerA
Name: serA_mRNA -> SerA
Description: Translation of SerA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product SerA protein nd nd
reactant serA_mRNA RNA nd nd
2-hydroxyglutarate ketoglutarate
Name: 2-hydroxyglutarate -> ketoglutarate
Description: Reaction transforming 2-hydroxyglutarate into ketoglutarate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product ketoglutarate simple molecule nd nd
reactant 2-hydroxyglutarate simple molecule nd nd
3-phospho-D-glycerate 3-p-OH-pyr
Name: 3-phospho-D-glycerate -> 3-p-OH-pyr
Description: Reaction transforming 3-phospho-D-glycerate into 3-p-OH-pyr
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product 3-p-OH-pyr simple molecule nd nd
reactant 3-phospho-D-glycerate simple molecule nd nd
gdhA_mRNA GdhA
Name: gdhA_mRNA -> GdhA
Description: Translation of GdhA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GdhA protein nd nd
reactant gdhA_mRNA RNA nd nd
nupC_mRNA NupC
Name: nupC_mRNA -> NupC
Description: Translation of NupC
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant nupC_mRNA RNA nd nd
product NupC protein nd nd
deoxyinosine_Ext deoxyinosine
Name: deoxyinosine_Ext -> deoxyinosine
Description: Transport of deoxyinosine_Ext through a bacterial membrane, leading to the presence of deoxyinosine inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product deoxyinosine simple molecule nd nd
reactant deoxyinosine_Ext simple molecule nd nd
inosine_Ext inosine
Name: inosine_Ext -> inosine
Description: Transport of inosine_Ext through a bacterial membrane, leading to the presence of inosine inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant inosine_Ext simple molecule nd nd
product inosine simple molecule nd nd
uridine_Ext uridine
Name: uridine_Ext -> uridine
Description: Transport of uridine_Ext through a bacterial membrane, leading to the presence of uridine inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product uridine simple molecule nd nd
reactant uridine_Ext simple molecule nd nd
thymidine_Ext thymidine
Name: thymidine_Ext -> thymidine
Description: Transport of thymidine_Ext through a bacterial membrane, leading to the presence of thymidine inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product thymidine simple molecule nd nd
reactant thymidine_Ext simple molecule nd nd
deoxyuridine_Ext deoxyuridine
Name: deoxyuridine_Ext -> deoxyuridine
Description: Transport of deoxyuridine_Ext through a bacterial membrane, leading to the presence of deoxyuridine inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant deoxyuridine_Ext simple molecule nd nd
product deoxyuridine simple molecule nd nd
d-cytidine_Ext d-cytidine
Name: d-cytidine_Ext -> d-cytidine
Description: Transport of d-cytidine_Ext through a bacterial membrane, leading to the presence of d-cytidine inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product d-cytidine simple molecule nd nd
reactant d-cytidine_Ext simple molecule nd nd
deoxyadenosine_Ext deoxyadenosine
Name: deoxyadenosine_Ext -> deoxyadenosine
Description: Transport of deoxyadenosine_Ext through a bacterial membrane, leading to the presence of deoxyadenosine inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant deoxyadenosine_Ext simple molecule nd nd
product deoxyadenosine simple molecule nd nd
cytidine_Ext cytidine
Name: cytidine_Ext -> cytidine
Description: Transport of cytidine_Ext through a bacterial membrane, leading to the presence of cytidine inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product cytidine simple molecule nd nd
reactant cytidine_Ext simple molecule nd nd
adenosine_Ext adenosine
Name: adenosine_Ext -> adenosine
Description: Transport of adenosine_Ext through a bacterial membrane, leading to the presence of adenosine inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product adenosine simple molecule nd nd
reactant adenosine_Ext simple molecule nd nd
asnC-mioC-mnmG_mRNA AsnC
Name: asnC-mioC-mnmG_mRNA -> AsnC
Description: Translation of AsnC
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant asnC-mioC-mnmG_mRNA RNA nd nd
product AsnC protein nd nd
gabDTP_mRNA GabT
Name: gabDTP_mRNA -> GabT
Description: Translation of GabT
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GabT protein nd nd
reactant gabDTP_mRNA RNA nd nd
ketoglutarate + GABA L-glutamate + succ-S-ald
Name: ketoglutarate + GABA -> L-glutamate + succ-S-ald
Description: Reaction transforming ketoglutarate, GABA into L-glutamate, succ-S-ald
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product L-glutamate simple molecule nd nd
reactant ketoglutarate simple molecule nd nd
product succ-S-ald simple molecule nd nd
reactant GABA simple molecule nd nd
ydcSTUV-patD_mRNA YdcS
Name: ydcSTUV-patD_mRNA -> YdcS
Description: Translation of YdcS
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant ydcSTUV-patD_mRNA RNA nd nd
product YdcS protein nd nd
gltBDF_mRNA GltB
Name: gltBDF_mRNA -> GltB
Description: Translation of GltB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gltBDF_mRNA RNA nd nd
product GltB protein nd nd
asnC_mRNA AsnC
Name: asnC_mRNA -> AsnC
Description: Translation of AsnC
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant asnC_mRNA RNA nd nd
product AsnC protein nd nd
asnC-mioC_mRNA AsnC
Name: asnC-mioC_mRNA -> AsnC
Description: Translation of AsnC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product AsnC protein nd nd
reactant asnC-mioC_mRNA RNA nd nd
asnC-mioC_mRNA MioC
Name: asnC-mioC_mRNA -> MioC
Description: Translation of MioC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MioC protein nd nd
reactant asnC-mioC_mRNA RNA nd nd



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