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MtlR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
D-fructose 6-phosphate D-mannitol_Ext MtlA MtlD MtlR mannitol-1-phosphate mtlADR mtlADR_mRNA PEP_Ext pyruvate


Gensor Unit       
Name: MtlR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0045892 - negative regulation of transcription, DNA-templated
GO:0050662 - coenzyme binding
GO:0015797 - mannitol transport
GO:0003824 - catalytic activity
GO:0009401 - phosphoenolpyruvate-dependent sugar phosphotransferase system
GO:0019594 - mannitol metabolic process
GO:0016020 - membrane
GO:0016491 - oxidoreductase activity
GO:0005887 - integral component of plasma membrane
GO:0016310 - phosphorylation
GO:0015795 - sorbitol transport
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Components:
Function Name Type
simple molecule pyruvate simple molecule


Reactions       
Showing 6 reactions
mtlADR mtlADR_mRNA
Name: mtlADR -> mtlADR_mRNA
Description: Transcription of transcription unit mtlADR; reaction inhibition by Cra.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product mtlADR_mRNA RNA nd nd
reactant mtlADR gene nd nd
mtlADR_mRNA MtlD
Name: mtlADR_mRNA -> MtlD
Description: Translation of MtlD
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant mtlADR_mRNA RNA nd nd
product MtlD protein nd nd
mannitol-1-phosphate D-fructose 6-phosphate
Name: mannitol-1-phosphate -> D-fructose 6-phosphate
Description: Reaction transforming mannitol-1-phosphate into D-fructose 6-phosphate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product D-fructose 6-phosphate simple molecule nd nd
reactant mannitol-1-phosphate simple molecule nd nd
mtlADR_mRNA MtlA
Name: mtlADR_mRNA -> MtlA
Description: Translation of MtlA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant mtlADR_mRNA RNA nd nd
product MtlA protein nd nd
PEP_Ext + D-mannitol_Ext mannitol-1-phosphate + pyruvate
Name: PEP_Ext + D-mannitol_Ext -> mannitol-1-phosphate + pyruvate
Description: Transport of PEP_Ext, D-mannitol_Ext through a bacterial membrane, leading to the presence of mannitol-1-phosphate, pyruvate inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant D-mannitol_Ext simple molecule nd nd
product mannitol-1-phosphate simple molecule nd nd
product pyruvate simple molecule nd nd
reactant PEP_Ext simple molecule nd nd
mtlADR_mRNA MtlR
Name: mtlADR_mRNA -> MtlR
Description: Translation of MtlR
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MtlR protein nd nd
reactant mtlADR_mRNA RNA nd nd



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