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MngR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
2(alpha-D-mannosyl-6-phosphate)-D-glycerate mannosylglycerate_Ext D-glycerate MngA MngB MngR alpha-D-mannose-6-phosphate mngAB mngAB_mRNA mngR mngR_mRNA PEP_Ext pyruvate


Gensor Unit       
Name: MngR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0045892 - negative regulation of transcription, DNA-templated
GO:0008270 - zinc ion binding
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0003824 - catalytic activity
GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0006013 - mannose metabolic process
GO:0016798 - hydrolase activity, acting on glycosyl bonds
GO:0003677 - DNA binding
GO:0030246 - carbohydrate binding
GO:0015923 - mannosidase activity
GO:0004559 - alpha-mannosidase activity
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Components:
Function Name Type
simple molecule pyruvate simple molecule


Reactions       
Showing 7 reactions
mngAB mngAB_mRNA
Name: mngAB -> mngAB_mRNA
Description: Transcription of transcription unit mngAB; reaction inhibition by MngR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant mngAB gene nd nd
product mngAB_mRNA RNA nd nd
mngR mngR_mRNA
Name: mngR -> mngR_mRNA
Description: Transcription of transcription unit mngR; reaction inhibition by MngR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product mngR_mRNA RNA nd nd
reactant mngR gene nd nd
mngAB_mRNA MngA
Name: mngAB_mRNA -> MngA
Description: Translation of MngA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MngA protein nd nd
reactant mngAB_mRNA RNA nd nd
PEP_Ext + mannosylglycerate_Ext 2(alpha-D-mannosyl-6-phosphate)-D-glycerate + pyruvate
Name: PEP_Ext + mannosylglycerate_Ext -> 2(alpha-D-mannosyl-6-phosphate)-D-glycerate + pyruvate
Description: Transport of PEP_Ext, mannosylglycerate_Ext through a bacterial membrane, leading to the presence of 2(alpha-D-mannosyl-6-phosphate)-D-glycerate, pyruvate inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant mannosylglycerate_Ext simple molecule nd nd
product 2(alpha-D-mannosyl-6-phosphate)-D-glycerate simple molecule nd nd
product pyruvate simple molecule nd nd
reactant PEP_Ext simple molecule nd nd
mngR_mRNA MngR
Name: mngR_mRNA -> MngR
Description: Translation of MngR
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant mngR_mRNA RNA nd nd
product MngR protein nd nd
mngAB_mRNA MngB
Name: mngAB_mRNA -> MngB
Description: Translation of MngB
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MngB protein nd nd
reactant mngAB_mRNA RNA nd nd
2(alpha-D-mannosyl-6-phosphate)-D-glycerate alpha-D-mannose-6-phosphate + D-glycerate
Name: 2(alpha-D-mannosyl-6-phosphate)-D-glycerate -> alpha-D-mannose-6-phosphate + D-glycerate
Description: Reaction transforming 2(alpha-D-mannosyl-6-phosphate)-D-glycerate into alpha-D-mannose-6-phosphate, D-glycerate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant 2(alpha-D-mannosyl-6-phosphate)-D-glycerate simple molecule nd nd
product alpha-D-mannose-6-phosphate simple molecule nd nd
product D-glycerate simple molecule nd nd



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