RegulonDB RegulonDB

Mlc Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
2-deoxy-D-glucose 6-phosphate 2-deoxyglucose_Ext Crr D-fructose 6-phosphate fru_Ext D-glucosamine-6-phosphate chitosamine_Ext D-mannose_Ext HPr MalT ManX ManY ManZ Mlc MurP N-acetyl-D-glucosamine-6-phosphate N-acetyl-D-mannosamine-6-phosphate NAcGlc_Ext N-acetyl-beta-D-mannosamine_Ext MurNAc-6-P MurNAc_Ext PtsG PtsH PtsI TreB YnfK alpha-D-mannose-6-phosphate beta-D-glucose-6-P beta-glucose_Ext malT malT_mRNA manXYZ manXYZ_mRNA methyl beta-D-glucoside 6-phosphate b-methyl-D-glucoside_Ext mlc mlc-ynfK mlc-ynfK_mRNA mlc_mRNA PEP_Ext ptsG ptsG_mRNA ptsHI-crr ptsHI-crr_mRNA pyruvate trehalose 6-phosphate trehalose_Ext Mlc EIIGlC ManZ ManY ManX PtsG Crr MurP Crr TreB Crr pyruvate pyruvate PEP_Ext PEP_Ext pyruvate pyruvate PEP_Ext pyruvate pyruvate EIIGlC


Gensor Unit       
Name: Mlc
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0043610 - regulation of carbohydrate utilization
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0016020 - membrane
GO:0009401 - phosphoenolpyruvate-dependent sugar phosphotransferase system
GO:0003824 - catalytic activity
GO:0005887 - integral component of plasma membrane
GO:0005355 - glucose transmembrane transporter activity
GO:0016310 - phosphorylation
GO:0005737 - cytoplasm
GO:0019197 - phosphoenolpyruvate-dependent sugar phosphotransferase complex
GO:0008965 - phosphoenolpyruvate-protein phosphotransferase activity
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Components:
Function Name Type
simple molecule trehalose_Ext simple molecule


Reactions       
Showing 33 reactions
malT malT_mRNA
Name: malT -> malT_mRNA
Description: Transcription of transcription unit malT; reaction inhibition by Mlc.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product malT_mRNA RNA nd nd
reactant malT gene nd nd
manXYZ manXYZ_mRNA
Name: manXYZ -> manXYZ_mRNA
Description: Transcription of transcription unit manXYZ; reaction inhibition by Cra.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant manXYZ gene nd nd
product manXYZ_mRNA RNA nd nd
mlc mlc_mRNA
Name: mlc -> mlc_mRNA
Description: Transcription of transcription unit mlc; reaction inhibition by Mlc.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product mlc_mRNA RNA nd nd
reactant mlc gene nd nd
mlc-ynfK mlc-ynfK_mRNA
Name: mlc-ynfK -> mlc-ynfK_mRNA
Description: Transcription of transcription unit mlc-ynfK; reaction inhibition by Mlc.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product mlc-ynfK_mRNA RNA nd nd
reactant mlc-ynfK gene nd nd
ptsG ptsG_mRNA
Name: ptsG -> ptsG_mRNA
Description: Transcription of transcription unit ptsG; reaction inhibition by Mlc.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product ptsG_mRNA RNA nd nd
reactant ptsG gene nd nd
ptsHI-crr ptsHI-crr_mRNA
Name: ptsHI-crr -> ptsHI-crr_mRNA
Description: Transcription of transcription unit ptsHI-crr; reaction inhibition by Cra.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product ptsHI-crr_mRNA RNA nd nd
reactant ptsHI-crr gene nd nd
Mlc + EIIGlC Mlc-EIIGlC
Name: Mlc + EIIGlC -> Mlc-EIIGlC
Description: Reaction transforming Mlc, EIIGlC into Mlc-EIIGlC
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product Mlc-EIIGlC complex nd nd
reactant EIIGlC protein nd nd
reactant Mlc protein nd nd
ptsHI-crr_mRNA PtsI
Name: ptsHI-crr_mRNA -> PtsI
Description: Translation of PtsI
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PtsI protein nd nd
reactant ptsHI-crr_mRNA RNA nd nd
manXYZ_mRNA ManZ
Name: manXYZ_mRNA -> ManZ
Description: Translation of ManZ
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant manXYZ_mRNA RNA nd nd
product ManZ protein nd nd
ManZ + ManY + ManX ManZ-ManY-ManX
Name: ManZ + ManY + ManX -> ManZ-ManY-ManX
Description: Reaction transforming ManZ, ManY, ManX into ManZ-ManY-ManX
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product ManZ-ManY-ManX complex nd nd
reactant ManX protein nd nd
reactant ManY protein nd nd
reactant ManZ protein nd nd
2-deoxyglucose_Ext + PEP_Ext pyruvate + 2-deoxy-D-glucose 6-phosphate
Name: 2-deoxyglucose_Ext + PEP_Ext -> pyruvate + 2-deoxy-D-glucose 6-phosphate
Description: Transport of 2-deoxyglucose_Ext, PEP_Ext through a bacterial membrane, leading to the presence of pyruvate, 2-deoxy-D-glucose 6-phosphate inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant 2-deoxyglucose_Ext simple molecule nd nd
product 2-deoxy-D-glucose 6-phosphate simple molecule nd nd
reactant PEP_Ext simple molecule nd nd
product pyruvate simple molecule nd nd
N-acetyl-beta-D-mannosamine_Ext + PEP_Ext N-acetyl-D-mannosamine-6-phosphate + pyruvate
Name: N-acetyl-beta-D-mannosamine_Ext + PEP_Ext -> N-acetyl-D-mannosamine-6-phosphate + pyruvate
Description: Transport of N-acetyl-beta-D-mannosamine_Ext, PEP_Ext through a bacterial membrane, leading to the presence of N-acetyl-D-mannosamine-6-phosphate, pyruvate inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant N-acetyl-beta-D-mannosamine_Ext simple molecule nd nd
product N-acetyl-D-mannosamine-6-phosphate simple molecule nd nd
reactant PEP_Ext simple molecule nd nd
product pyruvate simple molecule nd nd
chitosamine_Ext + PEP_Ext D-glucosamine-6-phosphate + pyruvate
Name: chitosamine_Ext + PEP_Ext -> D-glucosamine-6-phosphate + pyruvate
Description: Transport of chitosamine_Ext, PEP_Ext through a bacterial membrane, leading to the presence of D-glucosamine-6-phosphate, pyruvate inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product D-glucosamine-6-phosphate simple molecule nd nd
reactant chitosamine_Ext simple molecule nd nd
reactant PEP_Ext simple molecule nd nd
product pyruvate simple molecule nd nd
PEP_Ext + beta-glucose_Ext beta-D-glucose-6-P + pyruvate
Name: PEP_Ext + beta-glucose_Ext -> beta-D-glucose-6-P + pyruvate
Description: Transport of PEP_Ext, beta-glucose_Ext through a bacterial membrane, leading to the presence of beta-D-glucose-6-P, pyruvate inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant PEP_Ext simple molecule nd nd
reactant beta-glucose_Ext simple molecule nd nd
product pyruvate simple molecule nd nd
product beta-D-glucose-6-P simple molecule nd nd
PEP_Ext + NAcGlc_Ext N-acetyl-D-glucosamine-6-phosphate + pyruvate
Name: PEP_Ext + NAcGlc_Ext -> N-acetyl-D-glucosamine-6-phosphate + pyruvate
Description: Transport of PEP_Ext, NAcGlc_Ext through a bacterial membrane, leading to the presence of N-acetyl-D-glucosamine-6-phosphate, pyruvate inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant PEP_Ext simple molecule nd nd
product N-acetyl-D-glucosamine-6-phosphate simple molecule nd nd
product pyruvate simple molecule nd nd
reactant NAcGlc_Ext simple molecule nd nd
D-mannose_Ext + PEP_Ext alpha-D-mannose-6-phosphate + pyruvate
Name: D-mannose_Ext + PEP_Ext -> alpha-D-mannose-6-phosphate + pyruvate
Description: Transport of D-mannose_Ext, PEP_Ext through a bacterial membrane, leading to the presence of alpha-D-mannose-6-phosphate, pyruvate inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant D-mannose_Ext simple molecule nd nd
reactant PEP_Ext simple molecule nd nd
product alpha-D-mannose-6-phosphate simple molecule nd nd
product pyruvate simple molecule nd nd
fru_Ext + PEP_Ext D-fructose 6-phosphate + pyruvate
Name: fru_Ext + PEP_Ext -> D-fructose 6-phosphate + pyruvate
Description: Transport of fru_Ext, PEP_Ext through a bacterial membrane, leading to the presence of D-fructose 6-phosphate, pyruvate inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant PEP_Ext simple molecule nd nd
product D-fructose 6-phosphate simple molecule nd nd
product pyruvate simple molecule nd nd
reactant fru_Ext simple molecule nd nd
ptsG_mRNA PtsG
Name: ptsG_mRNA -> PtsG
Description: Translation of PtsG
Type: translation
Components:
Function Name Type Evidence Reference(s)
product PtsG protein nd nd
reactant ptsG_mRNA RNA nd nd
PtsG + Crr PtsG-Crr
Name: PtsG + Crr -> PtsG-Crr
Description: Reaction transforming PtsG, Crr into PtsG-Crr
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant PtsG protein nd nd
product PtsG-Crr complex nd nd
reactant Crr protein nd nd
b-methyl-D-glucoside_Ext + PEP_Ext methyl beta-D-glucoside 6-phosphate + pyruvate
Name: b-methyl-D-glucoside_Ext + PEP_Ext -> methyl beta-D-glucoside 6-phosphate + pyruvate
Description: Transport of b-methyl-D-glucoside_Ext, PEP_Ext through a bacterial membrane, leading to the presence of methyl beta-D-glucoside 6-phosphate, pyruvate inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product methyl beta-D-glucoside 6-phosphate simple molecule nd nd
reactant b-methyl-D-glucoside_Ext simple molecule nd nd
reactant PEP_Ext simple molecule nd nd
product pyruvate simple molecule nd nd
ptsHI-crr_mRNA Crr
Name: ptsHI-crr_mRNA -> Crr
Description: Translation of Crr
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant ptsHI-crr_mRNA RNA nd nd
product Crr protein nd nd
MurP + Crr MurP-Crr
Name: MurP + Crr -> MurP-Crr
Description: Reaction transforming MurP, Crr into MurP-Crr
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant Crr protein nd nd
reactant MurP protein nd nd
product MurP-Crr complex nd nd
PEP_Ext + MurNAc_Ext MurNAc-6-P + pyruvate
Name: PEP_Ext + MurNAc_Ext -> MurNAc-6-P + pyruvate
Description: Transport of PEP_Ext, MurNAc_Ext through a bacterial membrane, leading to the presence of MurNAc-6-P, pyruvate inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant PEP_Ext simple molecule nd nd
product MurNAc-6-P simple molecule nd nd
product pyruvate simple molecule nd nd
reactant MurNAc_Ext simple molecule nd nd
TreB + Crr TreB-Crr
Name: TreB + Crr -> TreB-Crr
Description: Reaction transforming TreB, Crr into TreB-Crr
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product TreB-Crr complex nd nd
reactant Crr protein nd nd
reactant TreB protein nd nd
PEP_Ext + trehalose_Ext trehalose 6-phosphate + pyruvate
Name: PEP_Ext + trehalose_Ext -> trehalose 6-phosphate + pyruvate
Description: Transport of PEP_Ext, trehalose_Ext through a bacterial membrane, leading to the presence of trehalose 6-phosphate, pyruvate inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product trehalose 6-phosphate simple molecule nd nd
reactant PEP_Ext simple molecule nd nd
product pyruvate simple molecule nd nd
reactant trehalose_Ext simple molecule nd nd
mlc-ynfK_mRNA YnfK
Name: mlc-ynfK_mRNA -> YnfK
Description: Translation of YnfK
Type: translation
Components:
Function Name Type Evidence Reference(s)
product YnfK protein nd nd
reactant mlc-ynfK_mRNA RNA nd nd
ptsHI-crr_mRNA HPr
Name: ptsHI-crr_mRNA -> HPr
Description: Translation of HPr
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant ptsHI-crr_mRNA RNA nd nd
product HPr protein nd nd
ptsHI-crr_mRNA PtsH
Name: ptsHI-crr_mRNA -> PtsH
Description: Translation of PtsH
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant ptsHI-crr_mRNA RNA nd nd
product PtsH protein nd nd
manXYZ_mRNA ManY
Name: manXYZ_mRNA -> ManY
Description: Translation of ManY
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant manXYZ_mRNA RNA nd nd
product ManY protein nd nd
mlc-ynfK_mRNA Mlc
Name: mlc-ynfK_mRNA -> Mlc
Description: Translation of Mlc
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant mlc-ynfK_mRNA RNA nd nd
product Mlc protein nd nd
manXYZ_mRNA ManX
Name: manXYZ_mRNA -> ManX
Description: Translation of ManX
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant manXYZ_mRNA RNA nd nd
product ManX protein nd nd
malT_mRNA MalT
Name: malT_mRNA -> MalT
Description: Translation of MalT
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MalT protein nd nd
reactant malT_mRNA RNA nd nd
mlc_mRNA Mlc
Name: mlc_mRNA -> Mlc
Description: Translation of Mlc
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant mlc_mRNA RNA nd nd
product Mlc protein nd nd



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