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Mlc Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
2-deoxy-D-glucose 6-phosphate 2-deoxyglucose_Ext Crr D-fructose 6-phosphate fru_Ext D-glucosamine-6-phosphate chitosamine_Ext D-mannose_Ext HPr MalT ManX ManY ManZ Mlc MurP N-acetyl-D-glucosamine-6-phosphate N-acetyl-D-mannosamine-6-phosphate NAcGlc_Ext N-acetyl-beta-D-mannosamine_Ext MurNAc-6-P MurNAc_Ext PtsG PtsH PtsI TreB YnfK alpha-D-mannose-6-phosphate beta-D-glucose-6-P beta-glucose_Ext malT malT_mRNA manXYZ manXYZ_mRNA methyl beta-D-glucoside 6-phosphate b-methyl-D-glucoside_Ext mlc mlc-ynfK mlc-ynfK_mRNA mlc_mRNA PEP_Ext ptsG ptsG_mRNA ptsHI-crr ptsHI-crr_mRNA pyruvate trehalose 6-phosphate trehalose_Ext Mlc EIIGlC ManZ ManY ManX PtsG Crr MurP Crr TreB Crr pyruvate pyruvate PEP_Ext PEP_Ext pyruvate pyruvate PEP_Ext pyruvate pyruvate EIIGlC


Gensor Unit       
Name: Mlc
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:0015764 - N-acetylglucosamine transport
GO:0009102 - biotin biosynthetic process
GO:0034219 - carbohydrate transmembrane transport
GO:0008643 - carbohydrate transport
GO:0032445 - fructose import
GO:0098708 - glucose import across plasma membrane
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cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0031234 - extrinsic component of cytoplasmic side of plasma membrane
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0016020 - membrane
GO:0019197 - phosphoenolpyruvate-dependent sugar phosphotransferase complex
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molecular_function GO:0003677 - DNA binding
GO:0003824 - catalytic activity
GO:0004141 - dethiobiotin synthase activity
GO:0008047 - enzyme activator activity
GO:0005355 - glucose transmembrane transporter activity
GO:0042802 - identical protein binding
GO:0016301 - kinase activity
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Components: Show/Hide Components Table (52 more...)
Function Name Type
simple_molecule α,α-trehalose 6-phosphate simple_molecule
simple_molecule α-D-glucosamine phosphate simple_molecule
simple_molecule α-D-mannose-6-P simple_molecule
simple_molecule α-D-mannose_Ext simple_molecule
simple_molecule 2-deoxy-D-glucose 6-phosphate simple_molecule
simple_molecule 2-deoxyglucose_Ext simple_molecule
protein Crr protein
simple_molecule EIIglc simple_molecule
simple_molecule HPr - phosphorylated_Ext simple_molecule
protein IIABMan protein
protein MalT protein
simple_molecule ManNAc-6-P simple_molecule
protein ManX protein
protein ManY protein
protein ManZ protein
complex ManZ-ManY-ManX complex
simple_molecule Methyl-D-glucoside_Ext simple_molecule
protein Mlc protein
complex Mlc-EIIglc complex
simple_molecule MurNAc-6-P simple_molecule
simple_molecule MurNAc_Ext simple_molecule
protein MurP protein
complex MurP-Crr complex
simple_molecule N-acetyl-α-D-glucosamine 6-phosphate simple_molecule
simple_molecule N-acetyl-beta-D-mannosamine_Ext simple_molecule
simple_molecule NAcGlc_Ext simple_molecule
protein PtsG protein
complex PtsG-Crr complex
simple_molecule PtsH simple_molecule
protein PtsI protein
protein TreB protein
complex TreB-Crr complex
protein YnfK protein
simple_molecule beta-D-glucose-6-P simple_molecule
simple_molecule beta-Levulose_Ext simple_molecule
simple_molecule beta-glucose_Ext simple_molecule
simple_molecule chitosamine_Ext simple_molecule
simple_molecule fructose-6-P simple_molecule
gene malT gene
RNA malT_mRNA RNA
gene manXYZ gene
RNA manXYZ_mRNA RNA
simple_molecule methyl α-D-glucoside 6-phosphate simple_molecule
gene mlc gene
gene mlc-ynfK gene
RNA mlc-ynfK_mRNA RNA
RNA mlc_mRNA RNA
gene ptsG gene
RNA ptsG_mRNA RNA
gene ptsHI-crr gene
RNA ptsHI-crr_mRNA RNA
simple_molecule trehalose_Ext simple_molecule


Reactions       
Showing 33 reactions
Mlc malT malT_mRNA
Name: malT -> malT_mRNA
Description: Transcription of transcription unit malT. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: malT - Mlc -> malT_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor Mlc protein nd nd
reactant malT gene nd nd
product malT_mRNA RNA nd nd
Mlc manXYZ manXYZ_mRNA
Name: manXYZ -> manXYZ_mRNA
Description: Transcription of transcription unit manXYZ. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: manXYZ - Mlc -> manXYZ_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor Mlc protein nd nd
reactant manXYZ gene nd nd
product manXYZ_mRNA RNA nd nd
Mlc mlc-ynfK mlc-ynfK_mRNA
Name: mlc-ynfK -> mlc-ynfK_mRNA
Description: Transcription of transcription unit mlc-ynfK. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: mlc-ynfK - Mlc -> mlc-ynfK_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor Mlc protein nd nd
reactant mlc-ynfK gene nd nd
product mlc-ynfK_mRNA RNA nd nd
Mlc ptsG ptsG_mRNA
Name: ptsG -> ptsG_mRNA
Description: Transcription of transcription unit ptsG. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: ptsG - Mlc -> ptsG_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor Mlc protein nd nd
reactant ptsG gene nd nd
product ptsG_mRNA RNA nd nd
Mlc ptsHI-crr ptsHI-crr_mRNA
Name: ptsHI-crr -> ptsHI-crr_mRNA
Description: Transcription of transcription unit ptsHI-crr. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: ptsHI-crr - Mlc -> ptsHI-crr_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor Mlc protein nd nd
reactant ptsHI-crr gene nd nd
product ptsHI-crr_mRNA RNA nd nd
EIIglc + Mlc Mlc-EIIglc
Name: EIIglc + Mlc -> Mlc-EIIglc
Description: Reaction transforming EIIglc, Mlc into Mlc-EIIglc
Type: state transition
Pathway Components: EIIglc + Mlc -> Mlc-EIIglc
Components:
Function Name Type Evidence Reference(s)
reactant EIIglc simple_molecule nd nd
reactant Mlc protein nd nd
product Mlc-EIIglc complex nd nd
Mlc mlc mlc_mRNA
Name: mlc -> mlc_mRNA
Description: Transcription of transcription unit mlc. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: mlc - Mlc -> mlc_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor Mlc protein nd nd
reactant mlc gene nd nd
product mlc_mRNA RNA nd nd
manXYZ_mRNA ManX
Name: manXYZ_mRNA -> ManX
Description: Translation of ManX
Type: translation
Pathway Components: manXYZ_mRNA -> ManX
Components:
Function Name Type Evidence Reference(s)
product ManX protein nd nd
reactant manXYZ_mRNA RNA nd nd
ManZ + ManX + ManY ManZ-ManY-ManX
Name: ManZ + ManX + ManY -> ManZ-ManY-ManX
Description: Reaction transforming ManZ, ManX, ManY into ManZ-ManY-ManX
Type: state transition
Pathway Components: ManZ + ManX + ManY -> ManZ-ManY-ManX
Components:
Function Name Type Evidence Reference(s)
reactant ManX protein nd nd
reactant ManY protein nd nd
reactant ManZ protein nd nd
product ManZ-ManY-ManX complex nd nd
ManZ-ManY-ManX HPr - phosphorylated_Ext + α-D-mannose_Ext α-D-mannose-6-P + PtsH
Name: HPr - phosphorylated_Ext + α-D-mannose_Ext -> α-D-mannose-6-P + PtsH
Description: Transport of HPr - phosphorylated_Ext, α-D-mannose_Ext through a bacterial membrane, leading to the presence of α-D-mannose-6-P, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + α-D-mannose_Ext - ManZ-ManY-ManX -> α-D-mannose-6-P + PtsH
Components:
Function Name Type Evidence Reference(s)
product α-D-mannose-6-P simple_molecule nd nd
reactant α-D-mannose_Ext simple_molecule nd nd
reactant HPr - phosphorylated_Ext simple_molecule nd nd
catalyzer ManZ-ManY-ManX complex nd nd
product PtsH simple_molecule nd nd
ManZ-ManY-ManX HPr - phosphorylated_Ext + 2-deoxyglucose_Ext 2-deoxy-D-glucose 6-phosphate + PtsH
Name: HPr - phosphorylated_Ext + 2-deoxyglucose_Ext -> 2-deoxy-D-glucose 6-phosphate + PtsH
Description: Transport of HPr - phosphorylated_Ext, 2-deoxyglucose_Ext through a bacterial membrane, leading to the presence of 2-deoxy-D-glucose 6-phosphate, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + 2-deoxyglucose_Ext - ManZ-ManY-ManX -> 2-deoxy-D-glucose 6-phosphate + PtsH
Components:
Function Name Type Evidence Reference(s)
product 2-deoxy-D-glucose 6-phosphate simple_molecule nd nd
reactant 2-deoxyglucose_Ext simple_molecule nd nd
reactant HPr - phosphorylated_Ext simple_molecule nd nd
catalyzer ManZ-ManY-ManX complex nd nd
product PtsH simple_molecule nd nd
ManZ-ManY-ManX Reactants ManNAc-6-P + PtsH
Name: N-acetyl-beta-D-mannosamine_Ext + HPr - phosphorylated_Ext -> ManNAc-6-P + PtsH
Description: Transport of N-acetyl-beta-D-mannosamine_Ext, HPr - phosphorylated_Ext through a bacterial membrane, leading to the presence of ManNAc-6-P, PtsH inside the cell.
Type: transport
Pathway Components: N-acetyl-beta-D-mannosamine_Ext + HPr - phosphorylated_Ext - ManZ-ManY-ManX -> ManNAc-6-P + PtsH
Components:
Function Name Type Evidence Reference(s)
reactant HPr - phosphorylated_Ext simple_molecule nd nd
product ManNAc-6-P simple_molecule nd nd
catalyzer ManZ-ManY-ManX complex nd nd
reactant N-acetyl-beta-D-mannosamine_Ext simple_molecule nd nd
product PtsH simple_molecule nd nd
ManZ-ManY-ManX HPr - phosphorylated_Ext + chitosamine_Ext α-D-glucosamine phosphate + PtsH
Name: HPr - phosphorylated_Ext + chitosamine_Ext -> α-D-glucosamine phosphate + PtsH
Description: Transport of HPr - phosphorylated_Ext, chitosamine_Ext through a bacterial membrane, leading to the presence of α-D-glucosamine phosphate, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + chitosamine_Ext - ManZ-ManY-ManX -> α-D-glucosamine phosphate + PtsH
Components:
Function Name Type Evidence Reference(s)
product α-D-glucosamine phosphate simple_molecule nd nd
reactant HPr - phosphorylated_Ext simple_molecule nd nd
catalyzer ManZ-ManY-ManX complex nd nd
product PtsH simple_molecule nd nd
reactant chitosamine_Ext simple_molecule nd nd
ManZ-ManY-ManX PtsG-Crr HPr - phosphorylated_Ext + beta-glucose_Ext beta-D-glucose-6-P + PtsH
Name: HPr - phosphorylated_Ext + beta-glucose_Ext -> beta-D-glucose-6-P + PtsH
Description: Transport of HPr - phosphorylated_Ext, beta-glucose_Ext through a bacterial membrane, leading to the presence of beta-D-glucose-6-P, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + beta-glucose_Ext - ManZ-ManY-ManX - PtsG-Crr -> beta-D-glucose-6-P + PtsH
Components:
Function Name Type Evidence Reference(s)
reactant HPr - phosphorylated_Ext simple_molecule nd nd
catalyzer ManZ-ManY-ManX complex nd nd
catalyzer PtsG-Crr complex nd nd
product PtsH simple_molecule nd nd
product beta-D-glucose-6-P simple_molecule nd nd
reactant beta-glucose_Ext simple_molecule nd nd
ManZ-ManY-ManX HPr - phosphorylated_Ext + NAcGlc_Ext N-acetyl-α-D-glucosamine 6-phosphate + PtsH
Name: HPr - phosphorylated_Ext + NAcGlc_Ext -> N-acetyl-α-D-glucosamine 6-phosphate + PtsH
Description: Transport of HPr - phosphorylated_Ext, NAcGlc_Ext through a bacterial membrane, leading to the presence of N-acetyl-α-D-glucosamine 6-phosphate, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + NAcGlc_Ext - ManZ-ManY-ManX -> N-acetyl-α-D-glucosamine 6-phosphate + PtsH
Components:
Function Name Type Evidence Reference(s)
reactant HPr - phosphorylated_Ext simple_molecule nd nd
catalyzer ManZ-ManY-ManX complex nd nd
product N-acetyl-α-D-glucosamine 6-phosphate simple_molecule nd nd
reactant NAcGlc_Ext simple_molecule nd nd
product PtsH simple_molecule nd nd
ManZ-ManY-ManX HPr - phosphorylated_Ext + beta-Levulose_Ext fructose-6-P + PtsH
Name: HPr - phosphorylated_Ext + beta-Levulose_Ext -> fructose-6-P + PtsH
Description: Transport of HPr - phosphorylated_Ext, beta-Levulose_Ext through a bacterial membrane, leading to the presence of fructose-6-P, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + beta-Levulose_Ext - ManZ-ManY-ManX -> fructose-6-P + PtsH
Components:
Function Name Type Evidence Reference(s)
reactant HPr - phosphorylated_Ext simple_molecule nd nd
catalyzer ManZ-ManY-ManX complex nd nd
product PtsH simple_molecule nd nd
reactant beta-Levulose_Ext simple_molecule nd nd
product fructose-6-P simple_molecule nd nd
manXYZ_mRNA IIABMan
Name: manXYZ_mRNA -> IIABMan
Description: Translation of IIABMan
Type: translation
Pathway Components: manXYZ_mRNA -> IIABMan
Components:
Function Name Type Evidence Reference(s)
product IIABMan protein nd nd
reactant manXYZ_mRNA RNA nd nd
manXYZ_mRNA ManY
Name: manXYZ_mRNA -> ManY
Description: Translation of ManY
Type: translation
Pathway Components: manXYZ_mRNA -> ManY
Components:
Function Name Type Evidence Reference(s)
product ManY protein nd nd
reactant manXYZ_mRNA RNA nd nd
manXYZ_mRNA ManZ
Name: manXYZ_mRNA -> ManZ
Description: Translation of ManZ
Type: translation
Pathway Components: manXYZ_mRNA -> ManZ
Components:
Function Name Type Evidence Reference(s)
product ManZ protein nd nd
reactant manXYZ_mRNA RNA nd nd
ptsHI-crr_mRNA PtsH
Name: ptsHI-crr_mRNA -> PtsH
Description: Translation of PtsH
Type: translation
Pathway Components: ptsHI-crr_mRNA -> PtsH
Components:
Function Name Type Evidence Reference(s)
product PtsH simple_molecule nd nd
reactant ptsHI-crr_mRNA RNA nd nd
ptsHI-crr_mRNA PtsI
Name: ptsHI-crr_mRNA -> PtsI
Description: Translation of PtsI
Type: translation
Pathway Components: ptsHI-crr_mRNA -> PtsI
Components:
Function Name Type Evidence Reference(s)
product PtsI simple_molecule nd nd
reactant ptsHI-crr_mRNA RNA nd nd
ptsHI-crr_mRNA Crr
Name: ptsHI-crr_mRNA -> Crr
Description: Translation of Crr
Type: translation
Pathway Components: ptsHI-crr_mRNA -> Crr
Components:
Function Name Type Evidence Reference(s)
product Crr protein nd nd
reactant ptsHI-crr_mRNA RNA nd nd
PtsG + Crr PtsG-Crr
Name: PtsG + Crr -> PtsG-Crr
Description: Reaction transforming PtsG, Crr into PtsG-Crr
Type: state transition
Pathway Components: PtsG + Crr -> PtsG-Crr
Components:
Function Name Type Evidence Reference(s)
reactant Crr protein nd nd
reactant PtsG protein nd nd
product PtsG-Crr complex nd nd
PtsG-Crr HPr - phosphorylated_Ext + Methyl-D-glucoside_Ext methyl α-D-glucoside 6-phosphate + PtsH
Name: HPr - phosphorylated_Ext + Methyl-D-glucoside_Ext -> methyl α-D-glucoside 6-phosphate + PtsH
Description: Transport of HPr - phosphorylated_Ext, Methyl-D-glucoside_Ext through a bacterial membrane, leading to the presence of methyl α-D-glucoside 6-phosphate, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + Methyl-D-glucoside_Ext - PtsG-Crr -> methyl α-D-glucoside 6-phosphate + PtsH
Components:
Function Name Type Evidence Reference(s)
reactant HPr - phosphorylated_Ext simple_molecule nd nd
reactant Methyl-D-glucoside_Ext simple_molecule nd nd
catalyzer PtsG-Crr complex nd nd
product PtsH simple_molecule nd nd
product methyl α-D-glucoside 6-phosphate simple_molecule nd nd
TreB + Crr TreB-Crr
Name: TreB + Crr -> TreB-Crr
Description: Reaction transforming TreB, Crr into TreB-Crr
Type: state transition
Pathway Components: TreB + Crr -> TreB-Crr
Components:
Function Name Type Evidence Reference(s)
reactant Crr protein nd nd
reactant TreB protein nd nd
product TreB-Crr complex nd nd
TreB-Crr HPr - phosphorylated_Ext + trehalose_Ext α,α-trehalose 6-phosphate + PtsH
Name: HPr - phosphorylated_Ext + trehalose_Ext -> α,α-trehalose 6-phosphate + PtsH
Description: Transport of HPr - phosphorylated_Ext, trehalose_Ext through a bacterial membrane, leading to the presence of α,α-trehalose 6-phosphate, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + trehalose_Ext - TreB-Crr -> α,α-trehalose 6-phosphate + PtsH
Components:
Function Name Type Evidence Reference(s)
product α,α-trehalose 6-phosphate simple_molecule nd nd
reactant HPr - phosphorylated_Ext simple_molecule nd nd
product PtsH simple_molecule nd nd
catalyzer TreB-Crr complex nd nd
reactant trehalose_Ext simple_molecule nd nd
MurP + Crr MurP-Crr
Name: MurP + Crr -> MurP-Crr
Description: Reaction transforming MurP, Crr into MurP-Crr
Type: state transition
Pathway Components: MurP + Crr -> MurP-Crr
Components:
Function Name Type Evidence Reference(s)
reactant Crr protein nd nd
reactant MurP protein nd nd
product MurP-Crr complex nd nd
MurP-Crr HPr - phosphorylated_Ext + MurNAc_Ext MurNAc-6-P + PtsH
Name: HPr - phosphorylated_Ext + MurNAc_Ext -> MurNAc-6-P + PtsH
Description: Transport of HPr - phosphorylated_Ext, MurNAc_Ext through a bacterial membrane, leading to the presence of MurNAc-6-P, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + MurNAc_Ext - MurP-Crr -> MurNAc-6-P + PtsH
Components:
Function Name Type Evidence Reference(s)
reactant HPr - phosphorylated_Ext simple_molecule nd nd
product MurNAc-6-P simple_molecule nd nd
reactant MurNAc_Ext simple_molecule nd nd
catalyzer MurP-Crr complex nd nd
product PtsH simple_molecule nd nd
mlc_mRNA Mlc
Name: mlc_mRNA -> Mlc
Description: Translation of Mlc
Type: translation
Pathway Components: mlc_mRNA -> Mlc
Components:
Function Name Type Evidence Reference(s)
product Mlc protein nd nd
reactant mlc_mRNA RNA nd nd
ptsG_mRNA PtsG
Name: ptsG_mRNA -> PtsG
Description: Translation of PtsG
Type: translation
Pathway Components: ptsG_mRNA -> PtsG
Components:
Function Name Type Evidence Reference(s)
product PtsG protein nd nd
reactant ptsG_mRNA RNA nd nd
malT_mRNA MalT
Name: malT_mRNA -> MalT
Description: Translation of MalT
Type: translation
Pathway Components: malT_mRNA -> MalT
Components:
Function Name Type Evidence Reference(s)
product MalT protein nd nd
reactant malT_mRNA RNA nd nd
mlc-ynfK_mRNA Mlc
Name: mlc-ynfK_mRNA -> Mlc
Description: Translation of Mlc
Type: translation
Pathway Components: mlc-ynfK_mRNA -> Mlc
Components:
Function Name Type Evidence Reference(s)
product Mlc protein nd nd
reactant mlc-ynfK_mRNA RNA nd nd
mlc-ynfK_mRNA YnfK
Name: mlc-ynfK_mRNA -> YnfK
Description: Translation of YnfK
Type: translation
Pathway Components: mlc-ynfK_mRNA -> YnfK
Components:
Function Name Type Evidence Reference(s)
product YnfK protein nd nd
reactant mlc-ynfK_mRNA RNA nd nd



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