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MhpR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
(2Z)-2-hydroxypenta-2,4-dienoate (2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate 2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate 2,3-dihydroxy-trans-cinnamate 2-oxo-4-pentenoate 3-(2,3-dihydroxyphenyl)propanoate 3-(3-hydroxyphenyl)propionate 3-hydroxy-trans-cinnamate 4-hydroxy-2-oxopentanoate MhpA MhpB MhpC MhpD MhpE MhpF MhpR acetaldehyde ac-CoA CoA fumarate mhpABCDFE mhpABCDFE_mRNA pyruvate succinate MhpR 3-(3-hydroxyphenyl)propionate


Gensor Unit       
Name: MhpR
Description: MhpR positively regulates the expression of genes involved in phenylpropanoid catabolic process in the presence of 3-(3-hydroxyphenyl) propionate. The presence of 3-(3-hydroxyphenyl) propionate induces the expression of genes related to the conversion of 3-(3-hydroxyphenyl) propionate to acetaldehyde, a precursor of acetyl-CoA.
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0052823 - 2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity
GO:0051213 - dioxygenase activity
GO:0003824 - catalytic activity
GO:0008684 - 2-oxopent-4-enoate hydratase activity
GO:0016491 - oxidoreductase activity
GO:0016833 - oxo-acid-lyase activity
GO:0051287 - NAD binding
GO:0005737 - cytoplasm
GO:0018771 - 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity
GO:0016829 - lyase activity
GO:0047070 - 3-carboxyethylcatechol 2,3-dioxygenase activity
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Components:
Function Name Type
RNA mhpABCDFE_mRNA RNA


Reactions       
Showing 9 reactions
2,3-DHP + MhpR MhpR-2,3-DHP
Name: 2,3-DHP + MhpR -> MhpR-2,3-DHP
Description: Reaction transforming 2,3-DHP, MhpR into MhpR-2,3-DHP
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product MhpR-2,3-DHP complex nd nd
reactant MhpR protein nd nd
reactant 2,3-DHP simple molecule nd nd
mhpABCDFE mhpABCDFE_mRNA
Name: mhpABCDFE -> mhpABCDFE_mRNA
Description: Transcription of transcription unit mhpABCDFE; reaction activation by MhpR-2,3-DHP.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant mhpABCDFE operon nd nd
product mhpABCDFE_mRNA RNA nd nd
MhpR + 3HPP MhpR-3HPP
Name: MhpR + 3HPP -> MhpR-3HPP
Description: Reaction transforming MhpR, 3HPP into MhpR-3HPP
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant 3HPP simple molecule nd nd
reactant MhpR protein nd nd
product MhpR-3HPP complex nd nd
mhpABCDFE_mRNA MhpA
Name: mhpABCDFE_mRNA -> MhpA
Description: Translation of MhpA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product mhpABCDFE_mRNA RNA nd nd
reactant mhpABCDFE_mRNA RNA nd nd
mhpABCDFE_mRNA MhpB
Name: mhpABCDFE_mRNA -> MhpB
Description: Translation of MhpB
Type: translation
Components:
Function Name Type Evidence Reference(s)
product mhpABCDFE_mRNA RNA nd nd
reactant mhpABCDFE_mRNA RNA nd nd
mhpABCDFE_mRNA MhpC
Name: mhpABCDFE_mRNA -> MhpC
Description: Translation of MhpC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product mhpABCDFE_mRNA RNA nd nd
reactant mhpABCDFE_mRNA RNA nd nd
mhpABCDFE_mRNA MhpD
Name: mhpABCDFE_mRNA -> MhpD
Description: Translation of MhpD
Type: translation
Components:
Function Name Type Evidence Reference(s)
product mhpABCDFE_mRNA RNA nd nd
reactant mhpABCDFE_mRNA RNA nd nd
mhpABCDFE_mRNA MhpF
Name: mhpABCDFE_mRNA -> MhpF
Description: Translation of MhpF
Type: translation
Components:
Function Name Type Evidence Reference(s)
product mhpABCDFE_mRNA RNA nd nd
reactant mhpABCDFE_mRNA RNA nd nd
mhpABCDFE_mRNA MhpE
Name: mhpABCDFE_mRNA -> MhpE
Description: Translation of MhpE
Type: translation
Components:
Function Name Type Evidence Reference(s)
product mhpABCDFE_mRNA RNA nd nd
reactant mhpABCDFE_mRNA RNA nd nd



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