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MelR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
lithium ion lithium ion_Ext MelA MelB MelR Sodium Sodium_Ext alpha-D-galactose beta-glucose melAB melAB_mRNA melR melR_mRNA melibiose melibiose_Ext a-methyl-D-galactoside a-methyl-D-galactoside_Ext b-methyl-D-galactoside b-methyl-D-galactoside_Ext melibiose MelR MelR melibiose


Gensor Unit       
Name: MelR
Classification:
Groups: GUs related to carbon source utilization
Gene Ontology Terms (GO): GO:0015765 - methylgalactoside transport
GO:0015486 - glycoside-pentoside-hexuronide:cation symporter activity
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0016020 - membrane
GO:0005887 - integral component of plasma membrane
GO:0004557 - alpha-galactosidase activity
GO:0016798 - hydrolase activity, acting on glycosyl bonds
GO:0043887 - melibiose:sodium symporter activity
GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0005829 - cytosol
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Components:
Function Name Type
simple molecule b-methyl-D-galactoside_Ext simple molecule


Reactions       
Showing 12 reactions
melAB melAB_mRNA
Name: melAB -> melAB_mRNA
Description: Transcription of transcription unit melAB; reaction inhibition by MelR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant melAB gene nd nd
product melAB_mRNA RNA nd nd
melR melR_mRNA
Name: melR -> melR_mRNA
Description: Transcription of transcription unit melR; reaction inhibition by MelR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product melR_mRNA RNA nd nd
reactant melR gene nd nd
MelR + melibiose MelR-melibiose
Name: MelR + melibiose -> MelR-melibiose
Description: Reaction transforming MelR, melibiose into MelR-melibiose
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product MelR-melibiose complex nd nd
reactant MelR protein nd nd
reactant melibiose simple molecule nd nd
melAB_mRNA MelA
Name: melAB_mRNA -> MelA
Description: Translation of MelA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant melAB_mRNA RNA nd nd
product MelA protein nd nd
melibiose alpha-D-galactose + beta-glucose
Name: melibiose -> alpha-D-galactose + beta-glucose
Description: Reaction transforming melibiose into alpha-D-galactose, beta-glucose
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product alpha-D-galactose simple molecule nd nd
product beta-glucose simple molecule nd nd
reactant melibiose simple molecule nd nd
melR_mRNA MelR
Name: melR_mRNA -> MelR
Description: Translation of MelR
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant melR_mRNA RNA nd nd
product MelR protein nd nd
melAB_mRNA MelB
Name: melAB_mRNA -> MelB
Description: Translation of MelB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant melAB_mRNA RNA nd nd
product MelB protein nd nd
lithium ion_Ext + melibiose_Ext lithium ion + melibiose
Name: lithium ion_Ext + melibiose_Ext -> lithium ion + melibiose
Description: Transport of lithium ion_Ext, melibiose_Ext through a bacterial membrane, leading to the presence of lithium ion, melibiose inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product lithium ion simple molecule nd nd
reactant lithium ion_Ext simple molecule nd nd
reactant melibiose_Ext simple molecule nd nd
product melibiose simple molecule nd nd
Sodium_Ext + melibiose_Ext Sodium + melibiose
Name: Sodium_Ext + melibiose_Ext -> Sodium + melibiose
Description: Transport of Sodium_Ext, melibiose_Ext through a bacterial membrane, leading to the presence of Sodium, melibiose inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product melibiose simple molecule nd nd
reactant melibiose_Ext simple molecule nd nd
reactant Sodium_Ext simple molecule nd nd
product Sodium simple molecule nd nd
b-methyl-D-galactoside_Ext + Sodium_Ext b-methyl-D-galactoside + Sodium
Name: b-methyl-D-galactoside_Ext + Sodium_Ext -> b-methyl-D-galactoside + Sodium
Description: Transport of b-methyl-D-galactoside_Ext, Sodium_Ext through a bacterial membrane, leading to the presence of b-methyl-D-galactoside, Sodium inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product b-methyl-D-galactoside simple molecule nd nd
reactant b-methyl-D-galactoside_Ext simple molecule nd nd
reactant Sodium_Ext simple molecule nd nd
product Sodium simple molecule nd nd
a-methyl-D-galactoside_Ext a-methyl-D-galactoside
Name: a-methyl-D-galactoside_Ext -> a-methyl-D-galactoside
Description: Transport of a-methyl-D-galactoside_Ext through a bacterial membrane, leading to the presence of a-methyl-D-galactoside inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant a-methyl-D-galactoside_Ext simple molecule nd nd
product a-methyl-D-galactoside simple molecule nd nd
melibiose_Ext melibiose
Name: melibiose_Ext -> melibiose
Description: Transport of melibiose_Ext through a bacterial membrane, leading to the presence of melibiose inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product melibiose simple molecule nd nd
reactant melibiose_Ext simple molecule nd nd



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