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MazE Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
CMP CTP GMP GTP Imp ITP MazE MazF MazG UMP UTP XMP XTP nucleoside 5'-monophosphate NTP dAMP dATP dCMP dCTP dGMP dGTP dIMP dITP TMP TTP dUMP dUTP PP mazEFG mazEFG_mRNA PP PP PP PP PP


Gensor Unit       
Name: MazE
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:0090502 - RNA phosphodiester bond hydrolysis, endonucleolytic
GO:0046047 - TTP catabolic process
GO:0046052 - UTP catabolic process
GO:0009267 - cellular response to starvation
GO:0046061 - dATP catabolic process
GO:0006203 - dGTP catabolic process
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molecular_function GO:0004521 - endoribonuclease activity
GO:0047429 - nucleoside-triphosphate diphosphatase activity
GO:0005515 - protein binding
Components: Show/Hide Components Table (29 more...)
Function Name Type
simple_molecule 5'-IMP simple_molecule
simple_molecule 5'-UMP simple_molecule
protein MazE protein
protein MazF protein
complex MazF-MazE complex
protein MazG protein
simple_molecule cytidine-triphosphate simple_molecule
simple_molecule cytidylate simple_molecule
simple_molecule dAMP simple_molecule
simple_molecule dATP simple_molecule
simple_molecule dCMP simple_molecule
simple_molecule dCTP simple_molecule
simple_molecule dGMP simple_molecule
simple_molecule dGTP simple_molecule
simple_molecule dIMP simple_molecule
simple_molecule dITP simple_molecule
simple_molecule dTMP simple_molecule
simple_molecule dTTP simple_molecule
simple_molecule dUMP simple_molecule
simple_molecule dUTP simple_molecule
simple_molecule diphosphate simple_molecule
simple_molecule inosine triphosphate simple_molecule
gene mazEFG gene
RNA mazEFG_mRNA RNA
simple_molecule mononucleotide simple_molecule
simple_molecule nucleoside triphosphate simple_molecule
simple_molecule uridine-triphosphate simple_molecule
simple_molecule xanthosine 5' triphosphate simple_molecule
simple_molecule xanthosine-5-P simple_molecule


Reactions       
Showing 16 reactions
MazE mazEFG mazEFG_mRNA
Name: mazEFG -> mazEFG_mRNA
Description: Transcription of transcription unit mazEFG. Reaction inhibition by MazE.
Type: transcription
Pathway Components: mazEFG - MazE -> mazEFG_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor MazE protein nd nd
reactant mazEFG gene nd nd
product mazEFG_mRNA RNA nd nd
mazEFG_mRNA MazE
Name: mazEFG_mRNA -> MazE
Description: Translation of MazE
Type: translation
Pathway Components: mazEFG_mRNA -> MazE
Components:
Function Name Type Evidence Reference(s)
product MazE protein nd nd
reactant mazEFG_mRNA RNA nd nd
MazF + MazE MazF-MazE
Name: MazF + MazE -> MazF-MazE
Description: Reaction transforming MazF, MazE into MazF-MazE
Type: state transition
Pathway Components: MazF + MazE -> MazF-MazE
Components:
Function Name Type Evidence Reference(s)
reactant MazE protein nd nd
reactant MazF protein nd nd
product MazF-MazE complex nd nd
mazEFG_mRNA MazF
Name: mazEFG_mRNA -> MazF
Description: Translation of MazF
Type: translation
Pathway Components: mazEFG_mRNA -> MazF
Components:
Function Name Type Evidence Reference(s)
product MazF protein nd nd
reactant mazEFG_mRNA RNA nd nd
mazEFG_mRNA MazG
Name: mazEFG_mRNA -> MazG
Description: Translation of MazG
Type: translation
Pathway Components: mazEFG_mRNA -> MazG
Components:
Function Name Type Evidence Reference(s)
product MazG protein nd nd
reactant mazEFG_mRNA RNA nd nd
MazG nucleoside triphosphate mononucleotide + diphosphate
Name: nucleoside triphosphate -> mononucleotide + diphosphate
Description: Reaction transforming nucleoside triphosphate into mononucleotide, diphosphate
Type: state transition
Pathway Components: nucleoside triphosphate - MazG -> mononucleotide + diphosphate
Components:
Function Name Type Evidence Reference(s)
catalyzer MazG protein nd nd
product diphosphate simple_molecule nd nd
product mononucleotide simple_molecule nd nd
reactant nucleoside triphosphate simple_molecule nd nd
MazG dITP diphosphate + dIMP
Name: dITP -> diphosphate + dIMP
Description: Reaction transforming dITP into diphosphate, dIMP
Type: state transition
Pathway Components: dITP - MazG -> diphosphate + dIMP
Components:
Function Name Type Evidence Reference(s)
catalyzer MazG protein nd nd
product dIMP simple_molecule nd nd
reactant dITP simple_molecule nd nd
product diphosphate simple_molecule nd nd
MazG inosine triphosphate diphosphate + 5'-IMP
Name: inosine triphosphate -> diphosphate + 5'-IMP
Description: Reaction transforming inosine triphosphate into diphosphate, 5'-IMP
Type: state transition
Pathway Components: inosine triphosphate - MazG -> diphosphate + 5'-IMP
Components:
Function Name Type Evidence Reference(s)
product 5'-IMP simple_molecule nd nd
catalyzer MazG protein nd nd
product diphosphate simple_molecule nd nd
reactant inosine triphosphate simple_molecule nd nd
MazG dCTP diphosphate + dCMP
Name: dCTP -> diphosphate + dCMP
Description: Reaction transforming dCTP into diphosphate, dCMP
Type: state transition
Pathway Components: dCTP - MazG -> diphosphate + dCMP
Components:
Function Name Type Evidence Reference(s)
catalyzer MazG protein nd nd
product dCMP simple_molecule nd nd
reactant dCTP simple_molecule nd nd
product diphosphate simple_molecule nd nd
MazG uridine-triphosphate diphosphate + 5'-UMP
Name: uridine-triphosphate -> diphosphate + 5'-UMP
Description: Reaction transforming uridine-triphosphate into diphosphate, 5'-UMP
Type: state transition
Pathway Components: uridine-triphosphate - MazG -> diphosphate + 5'-UMP
Components:
Function Name Type Evidence Reference(s)
product 5'-UMP simple_molecule nd nd
catalyzer MazG protein nd nd
product diphosphate simple_molecule nd nd
reactant uridine-triphosphate simple_molecule nd nd
MazG dTTP diphosphate + dTMP
Name: dTTP -> diphosphate + dTMP
Description: Reaction transforming dTTP into diphosphate, dTMP
Type: state transition
Pathway Components: dTTP - MazG -> diphosphate + dTMP
Components:
Function Name Type Evidence Reference(s)
catalyzer MazG protein nd nd
product dTMP simple_molecule nd nd
reactant dTTP simple_molecule nd nd
product diphosphate simple_molecule nd nd
MazG dGTP diphosphate + dGMP
Name: dGTP -> diphosphate + dGMP
Description: Reaction transforming dGTP into diphosphate, dGMP
Type: state transition
Pathway Components: dGTP - MazG -> diphosphate + dGMP
Components:
Function Name Type Evidence Reference(s)
catalyzer MazG protein nd nd
product dGMP simple_molecule nd nd
reactant dGTP simple_molecule nd nd
product diphosphate simple_molecule nd nd
MazG dAMP dATP diphosphate + dAMP
Name: dATP -> diphosphate + dAMP
Description: Reaction transforming dATP into diphosphate, dAMP
Type: state transition
Pathway Components: dATP - MazG - dAMP -> diphosphate + dAMP
Components:
Function Name Type Evidence Reference(s)
catalyzer MazG protein nd nd
inhibitor dAMP simple_molecule nd nd
product dAMP simple_molecule nd nd
reactant dATP simple_molecule nd nd
product diphosphate simple_molecule nd nd
MazG dUTP diphosphate + dUMP
Name: dUTP -> diphosphate + dUMP
Description: Reaction transforming dUTP into diphosphate, dUMP
Type: state transition
Pathway Components: dUTP - MazG -> diphosphate + dUMP
Components:
Function Name Type Evidence Reference(s)
catalyzer MazG protein nd nd
product dUMP simple_molecule nd nd
reactant dUTP simple_molecule nd nd
product diphosphate simple_molecule nd nd
MazG xanthosine 5' triphosphate xanthosine-5-P + diphosphate
Name: xanthosine 5' triphosphate -> xanthosine-5-P + diphosphate
Description: Reaction transforming xanthosine 5' triphosphate into xanthosine-5-P, diphosphate
Type: state transition
Pathway Components: xanthosine 5' triphosphate - MazG -> xanthosine-5-P + diphosphate
Components:
Function Name Type Evidence Reference(s)
catalyzer MazG protein nd nd
product diphosphate simple_molecule nd nd
reactant xanthosine 5' triphosphate simple_molecule nd nd
product xanthosine-5-P simple_molecule nd nd
MazG cytidine-triphosphate diphosphate + cytidylate
Name: cytidine-triphosphate -> diphosphate + cytidylate
Description: Reaction transforming cytidine-triphosphate into diphosphate, cytidylate
Type: state transition
Pathway Components: cytidine-triphosphate - MazG -> diphosphate + cytidylate
Components:
Function Name Type Evidence Reference(s)
catalyzer MazG protein nd nd
reactant cytidine-triphosphate simple_molecule nd nd
product cytidylate simple_molecule nd nd
product diphosphate simple_molecule nd nd



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