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MalI Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
cystathionine L-cysteine homo-cys MalI MalX MalY ammonia sulfide malI malI_mRNA malXY malXY_mRNA pyruvate glucose_Ext maltose_Ext maltose glucose


Gensor Unit       
Name: MalI
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:0034219 - carbohydrate transmembrane transport
GO:0009758 - carbohydrate utilization
GO:0046323 - glucose import
GO:0015768 - maltose transport
GO:0043433 - negative regulation of DNA binding transcription factor activity
GO:0045892 - negative regulation of transcription, DNA-templated
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cellular_component GO:0005887 - integral component of plasma membrane
GO:0005886 - plasma membrane
molecular_function GO:0055056 - D-glucose transmembrane transporter activity
GO:0003677 - DNA binding
GO:0080146 - L-cysteine desulfhydrase activity
GO:0004121 - cystathionine beta-lyase activity
GO:0005363 - maltose transmembrane transporter activity
GO:0005515 - protein binding
GO:0030170 - pyridoxal phosphate binding
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Components: Show/Hide Components Table (16 more...)
Function Name Type
protein MalI protein
protein MalX protein
protein MalY protein
simple_molecule cystathionine simple_molecule
simple_molecule cysteine simple_molecule
simple_molecule dehydroalanine simple_molecule
simple_molecule glucopyranose simple_molecule
simple_molecule glucopyranose_Ext simple_molecule
simple_molecule homo-cys simple_molecule
gene malI gene
RNA malI_mRNA RNA
gene malXY gene
RNA malXY_mRNA RNA
simple_molecule maltose simple_molecule
simple_molecule maltose_Ext simple_molecule
simple_molecule sulfide simple_molecule


Reactions       
Showing 9 reactions
MalI malI malI_mRNA
Name: malI -> malI_mRNA
Description: Transcription of transcription unit malI. Reaction inhibition by MalI.
Type: transcription
Pathway Components: malI - MalI -> malI_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor MalI protein nd nd
reactant malI gene nd nd
product malI_mRNA RNA nd nd
MalI malXY malXY_mRNA
Name: malXY -> malXY_mRNA
Description: Transcription of transcription unit malXY. Reaction inhibition by MalI.
Type: transcription
Pathway Components: malXY - MalI -> malXY_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor MalI protein nd nd
reactant malXY gene nd nd
product malXY_mRNA RNA nd nd
malI_mRNA MalI
Name: malI_mRNA -> MalI
Description: Translation of MalI
Type: translation
Pathway Components: malI_mRNA -> MalI
Components:
Function Name Type Evidence Reference(s)
product MalI protein nd nd
reactant malI_mRNA RNA nd nd
malXY_mRNA MalX
Name: malXY_mRNA -> MalX
Description: Translation of MalX
Type: translation
Pathway Components: malXY_mRNA -> MalX
Components:
Function Name Type Evidence Reference(s)
product MalX protein nd nd
reactant malXY_mRNA RNA nd nd
MalX maltose_Ext maltose
Name: maltose_Ext -> maltose
Description: Transport of maltose_Ext through a bacterial membrane, leading to the presence of maltose inside the cell.
Type: transport
Pathway Components: maltose_Ext - MalX -> maltose
Components:
Function Name Type Evidence Reference(s)
catalyzer MalX protein nd nd
product maltose simple_molecule nd nd
reactant maltose_Ext simple_molecule nd nd
MalX glucopyranose_Ext glucopyranose
Name: glucopyranose_Ext -> glucopyranose
Description: Transport of glucopyranose_Ext through a bacterial membrane, leading to the presence of glucopyranose inside the cell.
Type: transport
Pathway Components: glucopyranose_Ext - MalX -> glucopyranose
Components:
Function Name Type Evidence Reference(s)
catalyzer MalX protein nd nd
product glucopyranose simple_molecule nd nd
reactant glucopyranose_Ext simple_molecule nd nd
malXY_mRNA MalY
Name: malXY_mRNA -> MalY
Description: Translation of MalY
Type: translation
Pathway Components: malXY_mRNA -> MalY
Components:
Function Name Type Evidence Reference(s)
product MalY protein nd nd
reactant malXY_mRNA RNA nd nd
MalY cysteine cystathionine dehydroalanine + homo-cys
Name: cystathionine -> dehydroalanine + homo-cys
Description: Reaction transforming cystathionine into dehydroalanine, homo-cys
Type: state transition
Pathway Components: cystathionine - MalY - cysteine -> dehydroalanine + homo-cys
Components:
Function Name Type Evidence Reference(s)
catalyzer MalY protein nd nd
reactant cystathionine simple_molecule nd nd
inhibitor cysteine simple_molecule nd nd
product dehydroalanine simple_molecule nd nd
product homo-cys simple_molecule nd nd
MalY cysteine dehydroalanine + sulfide
Name: cysteine -> dehydroalanine + sulfide
Description: Reaction transforming cysteine into dehydroalanine, sulfide
Type: state transition
Pathway Components: cysteine - MalY -> dehydroalanine + sulfide
Components:
Function Name Type Evidence Reference(s)
catalyzer MalY protein nd nd
reactant cysteine simple_molecule nd nd
product dehydroalanine simple_molecule nd nd
product sulfide simple_molecule nd nd



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