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LsrR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
(R)-THMF (R)-THMF_Ext monomethyl-ester-of-trans-aconitate 3,4,4-trihydroxy-2-pentanone-5-phosphate 4,5-dihydroxy-2,3-pentanedione 4,5-dihydroxy-2,3-pentanedione-P 4-hydroxy-2,3-pentanedione-5-phosphate LsrA LsrB LsrC LsrD LsrF LsrG LsrK LsrR S-adenosyl-L-homocysteine S-adenosyl-L-methionine Tam lsrACDBFG-tam lsrACDBFG-tam_mRNA lsrRK lsrRK_mRNA phosphate trans-aconitate LsrR 4,5-dihydroxy-2,3-pentanedione-P LsrR 4,5-dihydroxy-2,3-pentanedione LsrB LsrD LsrC LsrA 3-hydroxy-2,4-pentanedione phosphate DHAP


Gensor Unit       
Name: LsrR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0003824 - catalytic activity
GO:0016020 - membrane
GO:0042597 - periplasmic space
GO:0044010 - single-species biofilm formation
GO:0009372 - quorum sensing
GO:0005737 - cytoplasm
GO:0016310 - phosphorylation
GO:0016829 - lyase activity
GO:0016887 - ATPase activity
GO:0003677 - DNA binding
GO:0005829 - cytosol
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Components:
Function Name Type
simple molecule DHAP simple molecule


Reactions       
Showing 20 reactions
LsrR + 4,5-dihydroxy-2,3-pentanedione LsrR-4,5-dihydroxy-2,3-pentanedione
Name: LsrR + 4,5-dihydroxy-2,3-pentanedione -> LsrR-4,5-dihydroxy-2,3-pentanedione
Description: Reaction transforming LsrR, 4,5-dihydroxy-2,3-pentanedione into LsrR-4,5-dihydroxy-2,3-pentanedione
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product LsrR-4,5-dihydroxy-2,3-pentanedione complex nd nd
reactant 4,5-dihydroxy-2,3-pentanedione simple molecule nd nd
reactant LsrR protein nd nd
lsrACDBFG-tam lsrACDBFG-tam_mRNA
Name: lsrACDBFG-tam -> lsrACDBFG-tam_mRNA
Description: Transcription of transcription unit lsrACDBFG-tam; reaction inhibition by LsrR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product lsrACDBFG-tam_mRNA RNA nd nd
reactant lsrACDBFG-tam gene nd nd
lsrRK lsrRK_mRNA
Name: lsrRK -> lsrRK_mRNA
Description: Transcription of transcription unit lsrRK; reaction inhibition by LsrR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product lsrRK_mRNA RNA nd nd
reactant lsrRK gene nd nd
LsrR + 4,5-dihydroxy-2,3-pentanedione-P LsrR-4,5-dihydroxy-2,3-pentanedione-P
Name: LsrR + 4,5-dihydroxy-2,3-pentanedione-P -> LsrR-4,5-dihydroxy-2,3-pentanedione-P
Description: Reaction transforming LsrR, 4,5-dihydroxy-2,3-pentanedione-P into LsrR-4,5-dihydroxy-2,3-pentanedione-P
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant 4,5-dihydroxy-2,3-pentanedione-P simple molecule nd nd
product LsrR-4,5-dihydroxy-2,3-pentanedione-P complex nd nd
reactant LsrR protein nd nd
lsrACDBFG-tam_mRNA Tam
Name: lsrACDBFG-tam_mRNA -> Tam
Description: Translation of Tam
Type: translation
Components:
Function Name Type Evidence Reference(s)
product Tam protein nd nd
reactant lsrACDBFG-tam_mRNA RNA nd nd
trans-aconitate + S-adenosyl-L-methionine monomethyl-ester-of-trans-aconitate + S-adenosyl-L-homocysteine
Name: trans-aconitate + S-adenosyl-L-methionine -> monomethyl-ester-of-trans-aconitate + S-adenosyl-L-homocysteine
Description: Reaction transforming trans-aconitate, S-adenosyl-L-methionine into monomethyl-ester-of-trans-aconitate, S-adenosyl-L-homocysteine
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant S-adenosyl-L-methionine simple molecule nd nd
product monomethyl-ester-of-trans-aconitate simple molecule nd nd
product S-adenosyl-L-homocysteine simple molecule nd nd
reactant trans-aconitate simple molecule nd nd
lsrACDBFG-tam_mRNA LsrD
Name: lsrACDBFG-tam_mRNA -> LsrD
Description: Translation of LsrD
Type: translation
Components:
Function Name Type Evidence Reference(s)
product LsrD protein nd nd
reactant lsrACDBFG-tam_mRNA RNA nd nd
LsrB + LsrD + LsrC + LsrA LsrB-LsrD-LsrC-LsrA
Name: LsrB + LsrD + LsrC + LsrA -> LsrB-LsrD-LsrC-LsrA
Description: Reaction transforming LsrB, LsrD, LsrC, LsrA into LsrB-LsrD-LsrC-LsrA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product LsrB-LsrD-LsrC-LsrA complex nd nd
reactant LsrA protein nd nd
reactant LsrB protein nd nd
reactant LsrD protein nd nd
reactant LsrC protein nd nd
(R)-THMF_Ext (R)-THMF + phosphate
Name: (R)-THMF_Ext -> (R)-THMF + phosphate
Description: Transport of (R)-THMF_Ext through a bacterial membrane, leading to the presence of (R)-THMF, phosphate inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product phosphate simple molecule nd nd
reactant (R)-THMF_Ext simple molecule nd nd
product (R)-THMF simple molecule nd nd
lsrACDBFG-tam_mRNA LsrB
Name: lsrACDBFG-tam_mRNA -> LsrB
Description: Translation of LsrB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant lsrACDBFG-tam_mRNA RNA nd nd
product LsrB protein nd nd
lsrACDBFG-tam_mRNA LsrG
Name: lsrACDBFG-tam_mRNA -> LsrG
Description: Translation of LsrG
Type: translation
Components:
Function Name Type Evidence Reference(s)
product LsrG protein nd nd
reactant lsrACDBFG-tam_mRNA RNA nd nd
4-hydroxy-2,3-pentanedione-5-phosphate 3,4,4-trihydroxy-2-pentanone-5-phosphate
Name: 4-hydroxy-2,3-pentanedione-5-phosphate -> 3,4,4-trihydroxy-2-pentanone-5-phosphate
Description: Reaction transforming 4-hydroxy-2,3-pentanedione-5-phosphate into 3,4,4-trihydroxy-2-pentanone-5-phosphate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant 4-hydroxy-2,3-pentanedione-5-phosphate simple molecule nd nd
product 3,4,4-trihydroxy-2-pentanone-5-phosphate simple molecule nd nd
lsrACDBFG-tam_mRNA LsrC
Name: lsrACDBFG-tam_mRNA -> LsrC
Description: Translation of LsrC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product LsrC protein nd nd
reactant lsrACDBFG-tam_mRNA RNA nd nd
lsrACDBFG-tam_mRNA LsrF
Name: lsrACDBFG-tam_mRNA -> LsrF
Description: Translation of LsrF
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant lsrACDBFG-tam_mRNA RNA nd nd
product LsrF protein nd nd
lsrRK_mRNA LsrK
Name: lsrRK_mRNA -> LsrK
Description: Translation of LsrK
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant lsrRK_mRNA RNA nd nd
product LsrK protein nd nd
4,5-dihydroxy-2,3-pentanedione 4-hydroxy-2,3-pentanedione-5-phosphate
Name: 4,5-dihydroxy-2,3-pentanedione -> 4-hydroxy-2,3-pentanedione-5-phosphate
Description: Reaction transforming 4,5-dihydroxy-2,3-pentanedione into 4-hydroxy-2,3-pentanedione-5-phosphate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product 4-hydroxy-2,3-pentanedione-5-phosphate simple molecule nd nd
reactant 4,5-dihydroxy-2,3-pentanedione simple molecule nd nd
lsrRK_mRNA LsrR
Name: lsrRK_mRNA -> LsrR
Description: Translation of LsrR
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant lsrRK_mRNA RNA nd nd
product LsrR protein nd nd
lsrACDBFG-tam_mRNA LsrA
Name: lsrACDBFG-tam_mRNA -> LsrA
Description: Translation of LsrA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant lsrACDBFG-tam_mRNA RNA nd nd
product LsrA protein nd nd
4-hydroxy-2,3-pentanedione-5-phosphate 3-hydroxy-2,4-pentanedione phosphate
Name: 4-hydroxy-2,3-pentanedione-5-phosphate -> 3-hydroxy-2,4-pentanedione phosphate
Description: Reaction transforming 4-hydroxy-2,3-pentanedione-5-phosphate into 3-hydroxy-2,4-pentanedione phosphate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant 4-hydroxy-2,3-pentanedione-5-phosphate simple molecule nd nd
product 3-hydroxy-2,4-pentanedione phosphate simple molecule nd nd
3-hydroxy-2,4-pentanedione phosphate DHAP
Name: 3-hydroxy-2,4-pentanedione phosphate -> DHAP
Description: Reaction transforming 3-hydroxy-2,4-pentanedione phosphate into DHAP
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product DHAP simple molecule nd nd
reactant 3-hydroxy-2,4-pentanedione phosphate simple molecule nd nd



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