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LldR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
(R)-lactate (R)-lactate_Ext (S)-lactate (S)-lactate_Ext L-lactose LldD LldP LldR a reduced electron acceptor an oxidized electron acceptor glycolate glycolate_Ext lldPRD lldPRD_mRNA pyruvate LldR L-lactose LldR


Gensor Unit       
Name: LldR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0035873 - lactate transmembrane transport
GO:0043879 - glycolate transmembrane transporter activity
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0003824 - catalytic activity
GO:0010181 - FMN binding
GO:0016020 - membrane
GO:0016491 - oxidoreductase activity
GO:0004459 - L-lactate dehydrogenase activity
GO:0005887 - integral component of plasma membrane
GO:0009061 - anaerobic respiration
GO:0015727 - lactate transport
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Components:
Function Name Type
simple molecule pyruvate simple molecule


Reactions       
Showing 9 reactions
lldPRD lldPRD_mRNA
Name: lldPRD -> lldPRD_mRNA
Description: Transcription of transcription unit lldPRD; reaction inhibition by LldR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant lldPRD gene nd nd
product lldPRD_mRNA RNA nd nd
LldR + L-lactose LldR-L-lactose
Name: LldR + L-lactose -> LldR-L-lactose
Description: Reaction transforming LldR, L-lactose into LldR-L-lactose
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant L-lactose simple molecule nd nd
product LldR-L-lactose complex nd nd
reactant LldR protein nd nd
lldPRD_mRNA LldP
Name: lldPRD_mRNA -> LldP
Description: Translation of LldP
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant lldPRD_mRNA RNA nd nd
product LldP protein nd nd
glycolate_Ext glycolate
Name: glycolate_Ext -> glycolate
Description: Transport of glycolate_Ext through a bacterial membrane, leading to the presence of glycolate inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product glycolate simple molecule nd nd
reactant glycolate_Ext simple molecule nd nd
D-lactate_Ext D-lactate
Name: D-lactate_Ext -> D-lactate
Description: Transport of D-lactate_Ext through a bacterial membrane, leading to the presence of D-lactate inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant D-lactate_Ext simple molecule nd nd
product D-lactate simple molecule nd nd
L-lactate_Ext L-lactate
Name: L-lactate_Ext -> L-lactate
Description: Transport of L-lactate_Ext through a bacterial membrane, leading to the presence of L-lactate inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant L-lactate_Ext simple molecule nd nd
product L-lactate simple molecule nd nd
lldPRD_mRNA LldR
Name: lldPRD_mRNA -> LldR
Description: Translation of LldR
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant lldPRD_mRNA RNA nd nd
product LldR protein nd nd
lldPRD_mRNA LldD
Name: lldPRD_mRNA -> LldD
Description: Translation of LldD
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant lldPRD_mRNA RNA nd nd
product LldD protein nd nd
L-lactate + an oxidized electron acceptor pyruvate + a reduced electron acceptor
Name: L-lactate + an oxidized electron acceptor -> pyruvate + a reduced electron acceptor
Description: Reaction transforming L-lactate, an oxidized electron acceptor into pyruvate, a reduced electron acceptor
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product a reduced electron acceptor simple molecule nd nd
reactant L-lactate simple molecule nd nd
product pyruvate simple molecule nd nd
reactant an oxidized electron acceptor simple molecule nd nd



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