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IlvY Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
(S)-2-acetolactate (R)-2,3-dihydroxy-isovalerate (R)-2,3-dihydroxy-3-methylvalerate (S)-2-aceto-2-hydroxybutanoate (S)-2-acetolactate IlvC IlvY ilvC ilvC_mRNA ilvY ilvY_mRNA IlvY (S)-2-acetolactate 2-dehydropantoate (R)-pantoate


Gensor Unit       
Name: IlvY
Description: IlvY positively regulates the expression of genes involved in reactions that are part of the L-isoleucine, L-valine, and phosphopantothenate biosynthesis pathways in the presence or absence of (S)-2-acetolactate. The reactions entail transformation of 2-dehydropantoate to (R)pantoate, of (S)-2-acetolactate to (R)-2,3-dihydroxy-isovalerate, and of (S)-2-aceto-2-hydroxybutanoate to (R)-2,3-dihydroxy-3-methylvalerate; these intermediates correspond to the phosphopantothenate, L-valine, and L-isoleucine biosynthetic pathways, respectively.
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:0009082 - branched-chain amino acid biosynthetic process
GO:0008652 - cellular amino acid biosynthetic process
GO:0009097 - isoleucine biosynthetic process
GO:0055114 - oxidation-reduction process
GO:0006355 - regulation of transcription, DNA-templated
GO:0006351 - transcription, DNA-templated
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cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0003677 - DNA binding
GO:0050661 - NADP binding
GO:0050662 - coenzyme binding
GO:0004455 - ketol-acid reductoisomerase activity
GO:0000287 - magnesium ion binding
GO:0016491 - oxidoreductase activity
GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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Components:
Function Name Type
RNA ilvY_mRNA RNA