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KdgR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
2-dehydro-3-deoxy-D-gluconate-6-phosphate 6-p gluconate CO2 D-glyceraldehyde 3-phosphate Eda Edd KdgR L-4-hydroxy-2-keto-glutarate eda eda_mRNA edd-eda edd-eda_mRNA glyoxylate oxalacetate pyruvate


Gensor Unit       
Name: KdgR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:0046177 - D-gluconate catabolic process
GO:0008152 - metabolic process
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016020 - membrane
molecular_function GO:0008675 - 2-dehydro-3-deoxy-phosphogluconate aldolase activity
GO:0008700 - 4-hydroxy-2-oxoglutarate aldolase activity
GO:0003824 - catalytic activity
GO:0016836 - hydro-lyase activity
GO:0042802 - identical protein binding
GO:0016829 - lyase activity
GO:0004456 - phosphogluconate dehydratase activity
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Components: Show/Hide Components Table (15 more...)
Function Name Type
simple_molecule 4-hydroxy-2-oxoglutarate simple_molecule
simple_molecule 6-p gluconate simple_molecule
simple_molecule CO2 simple_molecule
protein Eda protein
protein Edd protein
simple_molecule KDGP simple_molecule
protein KdgR protein
gene eda gene
RNA eda_mRNA RNA
gene edd-eda gene
RNA edd-eda_mRNA RNA
simple_molecule glyceraldehyde-P simple_molecule
simple_molecule glyoxylate simple_molecule
simple_molecule oxalacetate simple_molecule
simple_molecule pyruvate simple_molecule


Reactions       
Showing 9 reactions
KdgR eda eda_mRNA
Name: eda -> eda_mRNA
Description: Transcription of transcription unit eda. Reaction inhibition by KdgR.
Type: transcription
Pathway Components: eda - KdgR -> eda_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor KdgR protein nd nd
reactant eda gene nd nd
product eda_mRNA RNA nd nd
KdgR edd-eda edd-eda_mRNA
Name: edd-eda -> edd-eda_mRNA
Description: Transcription of transcription unit edd-eda. Reaction inhibition by KdgR.
Type: transcription
Pathway Components: edd-eda - KdgR -> edd-eda_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor KdgR protein nd nd
reactant edd-eda gene nd nd
product edd-eda_mRNA RNA nd nd
edd-eda_mRNA Edd
Name: edd-eda_mRNA -> Edd
Description: Translation of Edd
Type: translation
Pathway Components: edd-eda_mRNA -> Edd
Components:
Function Name Type Evidence Reference(s)
product Edd protein nd nd
reactant edd-eda_mRNA RNA nd nd
Edd 6-p gluconate KDGP
Name: 6-p gluconate -> KDGP
Description: Reaction transforming 6-p gluconate into KDGP
Type: state transition
Pathway Components: 6-p gluconate - Edd -> KDGP
Components:
Function Name Type Evidence Reference(s)
reactant 6-p gluconate simple_molecule nd nd
catalyzer Edd protein nd nd
product KDGP simple_molecule nd nd
edd-eda_mRNA Eda
Name: edd-eda_mRNA -> Eda
Description: Translation of Eda
Type: translation
Pathway Components: edd-eda_mRNA -> Eda
Components:
Function Name Type Evidence Reference(s)
product Eda protein nd nd
reactant edd-eda_mRNA RNA nd nd
Eda oxalacetate pyruvate + CO2
Name: oxalacetate -> pyruvate + CO2
Description: Reaction transforming oxalacetate into pyruvate, CO2
Type: state transition
Pathway Components: oxalacetate - Eda -> pyruvate + CO2
Components:
Function Name Type Evidence Reference(s)
product CO2 simple_molecule nd nd
catalyzer Eda protein nd nd
reactant oxalacetate simple_molecule nd nd
product pyruvate simple_molecule nd nd
6-p gluconate Eda glyceraldehyde-P KDGP glyceraldehyde-P + pyruvate
Name: KDGP -> glyceraldehyde-P + pyruvate
Description: Reaction transforming KDGP into glyceraldehyde-P, pyruvate
Type: state transition
Pathway Components: KDGP - Eda - 6-p gluconate - glyceraldehyde-P -> glyceraldehyde-P + pyruvate
Components:
Function Name Type Evidence Reference(s)
inhibitor 6-p gluconate simple_molecule nd nd
catalyzer Eda protein nd nd
reactant KDGP simple_molecule nd nd
inhibitor glyceraldehyde-P simple_molecule nd nd
product glyceraldehyde-P simple_molecule nd nd
product pyruvate simple_molecule nd nd
Eda glyoxylate pyruvate 4-hydroxy-2-oxoglutarate glyoxylate + pyruvate
Name: 4-hydroxy-2-oxoglutarate -> glyoxylate + pyruvate
Description: Reaction transforming 4-hydroxy-2-oxoglutarate into glyoxylate, pyruvate
Type: state transition
Pathway Components: 4-hydroxy-2-oxoglutarate - Eda - glyoxylate - pyruvate -> glyoxylate + pyruvate
Components:
Function Name Type Evidence Reference(s)
reactant 4-hydroxy-2-oxoglutarate simple_molecule nd nd
catalyzer Eda protein nd nd
inhibitor glyoxylate simple_molecule nd nd
product glyoxylate simple_molecule nd nd
inhibitor pyruvate simple_molecule nd nd
product pyruvate simple_molecule nd nd
eda_mRNA Eda
Name: eda_mRNA -> Eda
Description: Translation of Eda
Type: translation
Pathway Components: eda_mRNA -> Eda
Components:
Function Name Type Evidence Reference(s)
product Eda protein nd nd
reactant eda_mRNA RNA nd nd



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