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IclR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
L-malate AceA AceB AceK I-CIT IclR pyruvate a phosphorylated isocitrate dehydrogenase aceBAK aceBAK_mRNA ac-CoA an isocitrate dehydrogenase CoA glyoxylate iclR iclR_mRNA phosphate succinate IclR pyruvate IclR glyoxylate


Gensor Unit       
Name: IclR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0008772 - [isocitrate dehydrogenase (NADP+)] kinase activity
GO:0006099 - tricarboxylic acid cycle
GO:0003824 - catalytic activity
GO:0018105 - peptidyl-serine phosphorylation
GO:0004722 - protein serine/threonine phosphatase activity
GO:0016208 - AMP binding
GO:0016310 - phosphorylation
GO:0016829 - lyase activity
GO:0019752 - carboxylic acid metabolic process
GO:0005737 - cytoplasm
GO:0005829 - cytosol
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Components:
Function Name Type
simple molecule suc simple molecule


Reactions       
Showing 12 reactions
IclR + pyruvate IclR-pyruvate
Name: IclR + pyruvate -> IclR-pyruvate
Description: Reaction transforming IclR, pyruvate into IclR-pyruvate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant pyruvate simple molecule nd nd
product IclR-pyruvate complex nd nd
reactant IclR protein nd nd
aceBAK aceBAK_mRNA
Name: aceBAK -> aceBAK_mRNA
Description: Transcription of transcription unit aceBAK; reaction activation by Cra.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant aceBAK gene nd nd
product aceBAK_mRNA RNA nd nd
iclR iclR_mRNA
Name: iclR -> iclR_mRNA
Description: Transcription of transcription unit iclR; reaction activation by FadR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant iclR gene nd nd
product iclR_mRNA RNA nd nd
IclR + glyoxylate IclR-glyoxylate
Name: IclR + glyoxylate -> IclR-glyoxylate
Description: Reaction transforming IclR, glyoxylate into IclR-glyoxylate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant glyoxylate simple molecule nd nd
product IclR-glyoxylate complex nd nd
reactant IclR protein nd nd
aceBAK_mRNA AceA
Name: aceBAK_mRNA -> AceA
Description: Translation of AceA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product AceA protein nd nd
reactant aceBAK_mRNA RNA nd nd
I-CIT glyoxylate + suc
Name: I-CIT -> glyoxylate + suc
Description: Reaction transforming I-CIT into glyoxylate, suc
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant I-CIT simple molecule nd nd
product suc simple molecule nd nd
product glyoxylate simple molecule nd nd
aceBAK_mRNA AceK
Name: aceBAK_mRNA -> AceK
Description: Translation of AceK
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant aceBAK_mRNA RNA nd nd
product AceK protein nd nd
a phosphorylated isocitrate dehydrogenase an isocitrate dehydrogenase + phosphate
Name: a phosphorylated isocitrate dehydrogenase -> an isocitrate dehydrogenase + phosphate
Description: Reaction transforming a phosphorylated isocitrate dehydrogenase into an isocitrate dehydrogenase, phosphate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant a phosphorylated isocitrate dehydrogenase simple molecule nd nd
product an isocitrate dehydrogenase simple molecule nd nd
product phosphate simple molecule nd nd
an isocitrate dehydrogenase a phosphorylated isocitrate dehydrogenase
Name: an isocitrate dehydrogenase -> a phosphorylated isocitrate dehydrogenase
Description: Reaction transforming an isocitrate dehydrogenase into a phosphorylated isocitrate dehydrogenase
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product a phosphorylated isocitrate dehydrogenase simple molecule nd nd
reactant an isocitrate dehydrogenase simple molecule nd nd
iclR_mRNA IclR
Name: iclR_mRNA -> IclR
Description: Translation of IclR
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant iclR_mRNA RNA nd nd
product IclR protein nd nd
aceBAK_mRNA AceB
Name: aceBAK_mRNA -> AceB
Description: Translation of AceB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant aceBAK_mRNA RNA nd nd
product AceB protein nd nd
ac-CoA + glyoxylate L-malate + CoA
Name: ac-CoA + glyoxylate -> L-malate + CoA
Description: Reaction transforming ac-CoA, glyoxylate into L-malate, CoA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant ac-CoA simple molecule nd nd
reactant glyoxylate simple molecule nd nd
product CoA simple molecule nd nd
product L-malate simple molecule nd nd



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