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HcaR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol 2,3-dihydroxy-trans-cinnamate  3-(2,3-dihydroxyphenyl)propanoate 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate HCA HCA HcaB HcaC HcaD HcaE HcaF HcaR hcaEFCBD hcaEFCBD_mRNA hcaR hcaR_mRNA oxygen cinnamate HcaR HCA HcaC HcaD HcaF HcaE


Gensor Unit       
Name: HcaR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0018498 - 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity
GO:0051213 - dioxygenase activity
GO:0016708 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0045892 - negative regulation of transcription, DNA-templated
GO:0016491 - oxidoreductase activity
GO:0003824 - catalytic activity
GO:0051537 - 2 iron, 2 sulfur cluster binding
GO:0045893 - positive regulation of transcription, DNA-templated
GO:0003677 - DNA binding
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Components:
Function Name Type
simple molecule cinnamate simple molecule


Reactions       
Showing 14 reactions
hcaR hcaR_mRNA
Name: hcaR -> hcaR_mRNA
Description: Transcription of transcription unit hcaR; reaction inhibition by HcaR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant hcaR gene nd nd
product hcaR_mRNA RNA nd nd
HcaR + HCA HcaR-HCA
Name: HcaR + HCA -> HcaR-HCA
Description: Reaction transforming HcaR, HCA into HcaR-HCA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product HcaR-HCA complex nd nd
reactant HCA simple molecule nd nd
reactant HcaR protein nd nd
hcaEFCBD hcaEFCBD_mRNA
Name: hcaEFCBD -> hcaEFCBD_mRNA
Description: Transcription of transcription unit hcaEFCBD; reaction activation by HcaR-HCA.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product hcaEFCBD_mRNA RNA nd nd
reactant hcaEFCBD gene nd nd
hcaEFCBD_mRNA HcaF
Name: hcaEFCBD_mRNA -> HcaF
Description: Translation of HcaF
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant hcaEFCBD_mRNA RNA nd nd
product HcaF protein nd nd
HcaC + HcaD + HcaF + HcaE HcaC-HcaD-HcaF-HcaE
Name: HcaC + HcaD + HcaF + HcaE -> HcaC-HcaD-HcaF-HcaE
Description: Reaction transforming HcaC, HcaD, HcaF, HcaE into HcaC-HcaD-HcaF-HcaE
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant HcaD protein nd nd
reactant HcaC protein nd nd
product HcaC-HcaD-HcaF-HcaE complex nd nd
reactant HcaF protein nd nd
reactant HcaE protein nd nd
cinnamate + oxygen cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol
Name: cinnamate + oxygen -> cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol
Description: Reaction transforming cinnamate, oxygen into cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant cinnamate simple molecule nd nd
product cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol simple molecule nd nd
reactant oxygen simple molecule nd nd
HCA + oxygen 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate
Name: HCA + oxygen -> 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate
Description: Reaction transforming HCA, oxygen into 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate simple molecule nd nd
reactant HCA simple molecule nd nd
reactant oxygen simple molecule nd nd
hcaR_mRNA HcaR
Name: hcaR_mRNA -> HcaR
Description: Translation of HcaR
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant hcaR_mRNA RNA nd nd
product HcaR protein nd nd
hcaEFCBD_mRNA HcaC
Name: hcaEFCBD_mRNA -> HcaC
Description: Translation of HcaC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product HcaC protein nd nd
reactant hcaEFCBD_mRNA RNA nd nd
hcaEFCBD_mRNA HcaD
Name: hcaEFCBD_mRNA -> HcaD
Description: Translation of HcaD
Type: translation
Components:
Function Name Type Evidence Reference(s)
product HcaD protein nd nd
reactant hcaEFCBD_mRNA RNA nd nd
hcaEFCBD_mRNA HcaE
Name: hcaEFCBD_mRNA -> HcaE
Description: Translation of HcaE
Type: translation
Components:
Function Name Type Evidence Reference(s)
product HcaE protein nd nd
reactant hcaEFCBD_mRNA RNA nd nd
hcaEFCBD_mRNA HcaB
Name: hcaEFCBD_mRNA -> HcaB
Description: Translation of HcaB
Type: translation
Components:
Function Name Type Evidence Reference(s)
product HcaB protein nd nd
reactant hcaEFCBD_mRNA RNA nd nd
cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol 2,3-dihydroxy-trans-cinnamate
Name: cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol -> 2,3-dihydroxy-trans-cinnamate
Description: Reaction transforming cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol into 2,3-dihydroxy-trans-cinnamate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol simple molecule nd nd
product 2,3-dihydroxy-trans-cinnamate simple molecule nd nd
3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate 3-(2,3-dihydroxyphenyl)propanoate
Name: 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate -> 3-(2,3-dihydroxyphenyl)propanoate
Description: Reaction transforming 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate into 3-(2,3-dihydroxyphenyl)propanoate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product 3-(2,3-dihydroxyphenyl)propanoate simple molecule nd nd
reactant 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate simple molecule nd nd



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