RegulonDB RegulonDB

HcaR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol 2,3-dihydroxy-trans-cinnamate  3-(2,3-dihydroxyphenyl)propanoate 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate HCA HCA HcaB HcaC HcaD HcaE HcaF HcaR hcaEFCBD hcaEFCBD_mRNA hcaR hcaR_mRNA oxygen cinnamate HcaR HCA HcaC HcaD HcaF HcaE


Gensor Unit       
Name: HcaR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:0019380 - 3-phenylpropionate catabolic process
GO:0045892 - negative regulation of transcription, DNA-templated
GO:0055114 - oxidation-reduction process
GO:0045893 - positive regulation of transcription, DNA-templated
cellular_component GO:0005623 - cell
molecular_function GO:0051537 - 2 iron, 2 sulfur cluster binding
GO:0003677 - DNA binding
GO:0003700 - DNA binding transcription factor activity
GO:0051536 - iron-sulfur cluster binding
GO:0016491 - oxidoreductase activity
GO:0005515 - protein binding
Components: Show/Hide Components Table (18 more...)
Function Name Type
simple_molecule 2,3-DHP simple_molecule
simple_molecule 2,3-dihydroxycinnamic acid simple_molecule
simple_molecule 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate simple_molecule
protein HcaB protein
protein HcaC protein
complex HcaC-HcaD-HcaF-HcaE complex
protein HcaD protein
protein HcaE protein
protein HcaF protein
protein HcaR protein
simple_molecule cinnamate simple_molecule
simple_molecule cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol simple_molecule
gene hcaEFCBD gene
RNA hcaEFCBD_mRNA RNA
gene hcaR gene
RNA hcaR_mRNA RNA
simple_molecule hydrocinnamate simple_molecule
simple_molecule oxygen simple_molecule


Reactions       
Showing 13 reactions
HcaR hcaEFCBD hcaEFCBD_mRNA
Name: hcaEFCBD -> hcaEFCBD_mRNA
Description: Transcription of transcription unit hcaEFCBD. Reaction activation by HcaR.
Type: transcription
Pathway Components: hcaEFCBD - HcaR -> hcaEFCBD_mRNA
Components:
Function Name Type Evidence Reference(s)
activator HcaR protein nd nd
reactant hcaEFCBD gene nd nd
product hcaEFCBD_mRNA RNA nd nd
HcaR hcaR hcaR_mRNA
Name: hcaR -> hcaR_mRNA
Description: Transcription of transcription unit hcaR. Reaction inhibition by HcaR.
Type: transcription
Pathway Components: hcaR - HcaR -> hcaR_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor HcaR protein nd nd
reactant hcaR gene nd nd
product hcaR_mRNA RNA nd nd
hcaEFCBD_mRNA HcaE
Name: hcaEFCBD_mRNA -> HcaE
Description: Translation of HcaE
Type: translation
Pathway Components: hcaEFCBD_mRNA -> HcaE
Components:
Function Name Type Evidence Reference(s)
product HcaE protein nd nd
reactant hcaEFCBD_mRNA RNA nd nd
HcaE + HcaC + HcaF + HcaD HcaC-HcaD-HcaF-HcaE
Name: HcaE + HcaC + HcaF + HcaD -> HcaC-HcaD-HcaF-HcaE
Description: Reaction transforming HcaE, HcaC, HcaF, HcaD into HcaC-HcaD-HcaF-HcaE
Type: state transition
Pathway Components: HcaE + HcaC + HcaF + HcaD -> HcaC-HcaD-HcaF-HcaE
Components:
Function Name Type Evidence Reference(s)
reactant HcaC protein nd nd
product HcaC-HcaD-HcaF-HcaE complex nd nd
reactant HcaD protein nd nd
reactant HcaE protein nd nd
reactant HcaF protein nd nd
HcaC-HcaD-HcaF-HcaE cinnamate + oxygen Products
Name: cinnamate + oxygen -> cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol
Description: Reaction transforming cinnamate, oxygen into cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol
Type: state transition
Pathway Components: cinnamate + oxygen - HcaC-HcaD-HcaF-HcaE -> cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol
Components:
Function Name Type Evidence Reference(s)
catalyzer HcaC-HcaD-HcaF-HcaE complex nd nd
reactant cinnamate simple_molecule nd nd
product cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol simple_molecule nd nd
reactant oxygen simple_molecule nd nd
HcaC-HcaD-HcaF-HcaE hydrocinnamate + oxygen Products
Name: hydrocinnamate + oxygen -> 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate
Description: Reaction transforming hydrocinnamate, oxygen into 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate
Type: state transition
Pathway Components: hydrocinnamate + oxygen - HcaC-HcaD-HcaF-HcaE -> 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate
Components:
Function Name Type Evidence Reference(s)
product 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate simple_molecule nd nd
catalyzer HcaC-HcaD-HcaF-HcaE complex nd nd
reactant hydrocinnamate simple_molecule nd nd
reactant oxygen simple_molecule nd nd
hcaEFCBD_mRNA HcaF
Name: hcaEFCBD_mRNA -> HcaF
Description: Translation of HcaF
Type: translation
Pathway Components: hcaEFCBD_mRNA -> HcaF
Components:
Function Name Type Evidence Reference(s)
product HcaF protein nd nd
reactant hcaEFCBD_mRNA RNA nd nd
hcaEFCBD_mRNA HcaC
Name: hcaEFCBD_mRNA -> HcaC
Description: Translation of HcaC
Type: translation
Pathway Components: hcaEFCBD_mRNA -> HcaC
Components:
Function Name Type Evidence Reference(s)
product HcaC protein nd nd
reactant hcaEFCBD_mRNA RNA nd nd
hcaEFCBD_mRNA HcaB
Name: hcaEFCBD_mRNA -> HcaB
Description: Translation of HcaB
Type: translation
Pathway Components: hcaEFCBD_mRNA -> HcaB
Components:
Function Name Type Evidence Reference(s)
product HcaB protein nd nd
reactant hcaEFCBD_mRNA RNA nd nd
HcaB Reactants 2,3-dihydroxycinnamic acid
Name: cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol -> 2,3-dihydroxycinnamic acid
Description: Reaction transforming cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol into 2,3-dihydroxycinnamic acid
Type: state transition
Pathway Components: cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol - HcaB -> 2,3-dihydroxycinnamic acid
Components:
Function Name Type Evidence Reference(s)
product 2,3-dihydroxycinnamic acid simple_molecule nd nd
catalyzer HcaB protein nd nd
reactant cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol simple_molecule nd nd
HcaB Reactants 2,3-DHP
Name: 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate -> 2,3-DHP
Description: Reaction transforming 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate into 2,3-DHP
Type: state transition
Pathway Components: 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate - HcaB -> 2,3-DHP
Components:
Function Name Type Evidence Reference(s)
product 2,3-DHP simple_molecule nd nd
reactant 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate simple_molecule nd nd
catalyzer HcaB protein nd nd
hcaEFCBD_mRNA HcaD
Name: hcaEFCBD_mRNA -> HcaD
Description: Translation of HcaD
Type: translation
Pathway Components: hcaEFCBD_mRNA -> HcaD
Components:
Function Name Type Evidence Reference(s)
product HcaD protein nd nd
reactant hcaEFCBD_mRNA RNA nd nd
hcaR_mRNA HcaR
Name: hcaR_mRNA -> HcaR
Description: Translation of HcaR
Type: translation
Pathway Components: hcaR_mRNA -> HcaR
Components:
Function Name Type Evidence Reference(s)
product HcaR protein nd nd
reactant hcaR_mRNA RNA nd nd



RegulonDB